Tag: Autophagy

Researchers have found that kinesin family member 9 (KIF9), a protein that diminishes with aging, is instrumental in allowing cells to consume harmful proteins and fights Alzheimer's in a mouse model. Consuming amyloids before they become a problem What is Autophagy?Autophagy, derived from ancient Greek, means "eating of self". Autophagy is the way cells break...

Boosting a key autophagy-related protein discourages a core component of Alzheimer's from taking hold, according to a study published in Aging Cell. Taking out the trash Autophagy is the maintenance process of the cell, in which autophagosomes engulf unwanted organelles and other material and fuse together with lysosomes to be digested. As these unwanted components...

Researchers have published a method of rescuing cells from damaged mitochondria and cellular senescence, potentially alleviating major aspects of aging. Bad mitochondria must be consumed What is Autophagy?Autophagy, derived from ancient Greek, means "eating of self". Autophagy is the way cells break down misbehaving or nonfunctional organelles and proteins in the cell. This means that...

A study published in Human Nutrition & Metabolism found that prolonged intermittent fasting causes the expression of genes involved in autophagy, the inflammasome, and senescence to change [1]. Fasting your way to better health and longevity? Previous research has linked fasting to delaying the onset of age-related diseases and longevity along with positive outcomes in...

A study published in Aging Cell has reported that older people with better regulated autophagy in their skeletal muscles have less age-related frailty. Taking out the trash What is Autophagy?Autophagy, derived from ancient Greek, means "eating of self". Autophagy is the way cells break down misbehaving or nonfunctional organelles and proteins in the cell. This...

Experimenting in vitro and in mice, scientists have found that ovarian aging is linked to increased autophagy and apoptosis in granulosa cells and that it can be reversed by an estrogen receptor inhibitor [1]. When ovaries get tired Female reproductive aging is an intriguing phenomenon that remains understudied, although things have been changing recently. In...