Tag: NRF2

In Aging Cell, researchers have published detailed information on why the antioxidant pyrroloquinoline quinone (PQQ), which is known to be safe in humans, alleviates age-related disc degeneration in mice. A return to antioxidants Oxidative stress was once considered to be the core of aging, a concept that has since been supplanted by more detailed and...

In Nature Communications, researchers have published their discovery of a compound found in carrots that promotes mitochondrial health and improves the physical abilities of older mice. Walking down the caloric restriction pathway Although it is difficult to establish in human beings, caloric restriction is one of the most well-known interventions known to be effective across...

Scientists have successfully reversed the decline in cellular stress response in drosophila flies [1]. Our cells rely on epigenetic regulation to do their various jobs: while a muscle cell has the same genome as a liver cell, the difference in gene expression is what sets them apart. With age, these complex epigenetic patterns can go...

Activation of a genetic pathway controlled by the NRF2 gene reduces age-related hearing loss, according to a new study [1]. In the long run, drugs or treatments that target this pathway could help us keep our hearing sharp as we get older. It's getting harder and harder to hear Age-related hearing loss is extremely common,...