Tag: Tissue Regeneration

Scientists have analyzed the differences between mammalian species that can regrow ear tissue after injury and those that cannot. Their findings can pave the way for novel regenerative therapies [1]. The lost art of regeneration Many animal species have amazing regenerative abilities. On the one side of the spectrum sit planarian worms: slice them up,...

Michael Levin, professor at Tufts University and director of Allen Discovery Center, has been working for years on how bioelectrical patterns affect development and aging. His research proves that this often-overlooked part of biology is immensely important and that mastering its mechanisms might one day do wonders for human health and longevity. By manipulating ion...

In a rat experiment, researchers publishing in Aging Cell have found that senescent cells and SASP factors are key in regenerating knee cartilage. Not always negative Cellular senescence is widely known to have negative effects, to the point that it is one of the hallmarks of aging. In fact, rather than protecting cartilage, cellular senescence...

In Cell, a team of researchers, including the founders of the biotech company HepaRegeniX, has published a paper on HRX215, a molecule that encourages liver regeneration. When the liver doesn't regenerate The researchers note that the liver has a "nearly unlimited regenerative potential" under healthy circumstances. However, when its microenvironment changes due to damage, this...

Scientists have demonstrated that full-body regeneration in cnidarians, a group of animals that includes the jellyfish and hydra, can be driven by signals from senescent cells [1]. This might be the original purpose of cellular senescence. Why can’t we regrow our arms? There are many examples of amazing regenerative abilities in the animal kingdom, but...

A paper published today in Nature Aging has shown that a macrophage-regulating factor has a significant impact on muscle regeneration. Healing slows with aging The researchers note two key reasons for the decline of regenerative abilities with aging. The first is stem cell exhaustion, the gradual depletion of stem cells and ensuing lack of functional...