September 02, 2024
In Aging, researchers have described how a derivative of caffeic acid inhibits osteoclasts, the cells that break down bone. A modification of a tested compound We have recently published new information on what triggers the imbalance between bone-destroying osteoclasts and bone-building osteoblasts. This is a well-known problem with aging, and researchers around the world have...
August 26, 2024
Researchers have described a relationship between the NAD+ regulator CD38, mitochondrial function, and the gradual destruction of bone in Aging Cell. Inflammation up, bone mass down Nicotinamide Adenine Dinucleotide (NAD): Benefits and ResearchNicotinamide adenine dinucleotide (NAD) is a coenzyme found in all living cells. It is a dinucleotide, which means that it consists of two...
June 12, 2024
A team of researchers has found that corylin, a compound previously investigated for its anti-senesence properties, is effective against osteoporosis in a mouse model. A return to a well-known compound Corylin is a compound that was first discovered in Psoralea corylifolia, a plant commonly used in Chinese traditional medicine. This is far from the first...
March 28, 2024
In Aging, researchers have published negative results on the long-term use of methylene blue and mitoquinone (MitoQ), two popular antioxidants, to sustain bone health in mice. Oxidative stress and bone health Previous work has found that oxidative stress, which is commonly associated with age-related disease and damage, is related to bone diseases. Substantial amounts of...
November 02, 2023
Scientists have demonstrated that hyperbaric oxygen therapy can reverse some aspects of bone deterioration caused by aging and obesity in rats [1]. Under pressure Hyperbaric oxygen therapy (HBOT) involves placing the patient in a chamber with elevated levels of oxygen and atmospheric pressure. HBOT has been approved for treating certain conditions, such as air embolism,...
August 11, 2023
Studying a large British cohort, scientists have found that vegetarians have an increased risk of hip fracture compared to regular meat eaters, but pescatarians and occasional meat eaters do not [1]. Diet and brittle bones Hip fracture is one of the injuries most associated with aging. While hip fracture itself is treatable, it can easily...