November 27, 2023
In Nature Communications, researchers have explained how epigenetic drift and disorder are associated with shorter lifespans across species. When randomness is a problem We have previously reported on research demonstrating that epigenetic clocks are most likely to be measuring noise. This paper builds on that concept, citing previous research showing that this gradual epigenetic drift...
July 21, 2023
A group of researchers led by Morgan Levine of Altos Labs has created a set of methylation clocks that can detect various aging patterns [1]. The less-than-perfect revolution The discovery that genome methylation patterns correlate with various processes of aging led to the development of methylation (epigenetic) clocks. They first appeared more than a decade...
June 29, 2023
A study recently published in Aging Cell has discovered an entirely new method of looking at methylation and experimented with multiple ways of analyzing it. Not just a clock Why We Age: Epigenetic AlterationsEpigenetic alterations are age-related changes in gene expression that harm the fundamental functions of cells and increase the risk of cancer and...
February 02, 2022
A study published in the American Journal of Clinical Nutrition examined the relationship between diet quality and epigenetic aging clocks [1]. This study used data from the Framingham Heart Study Offspring Cohort. This specific study noted the Dietary Approaches to Stop Hypertension (DASH) scores, which are derived from a food frequency questionnaire (FFQ), of 1,995...
December 13, 2021
Researchers publishing in Aging Cell have discovered how and why oleuropein (OLP), a polyphenol derived from olives, ameliorates epigenetic kidney aging. KidneyThe kidney's main function is to filter waste products out of the blood and deliver the resulting urine to the bladder. The functional unit of the kidney is called the nephron, and each kidney...
December 03, 2021
A commercially available alpha-ketoglutarate-based supplement has been shown to roll back biological age by 7 years on average in a retrospective human study [1]. Live slower, die later Though metformin and rapamycin are getting most of the attention in the longevity field today, alpha-ketoglutarate (AKG) has emerged as another candidate longevity drug. These three molecules have...