Tag: Hypoxia

In GeroScience, researchers have described how turning off a specific protein prevents mice from getting obese in old age. Mimicking hypoxia Hypoxia-inducible factors (HIFs) are a collection of three proteins that are sensitive to oxygen, and, like their name suggests, they normally activate when a cell is operating in a low-oxygen environment. The gene EGLN1...

Scientists have demonstrated that hyperbaric oxygen therapy can reverse some aspects of bone deterioration caused by aging and obesity in rats [1]. Under pressure Hyperbaric oxygen therapy (HBOT) involves placing the patient in a chamber with elevated levels of oxygen and atmospheric pressure. HBOT has been approved for treating certain conditions, such as air embolism,...

Scientists have found that continuous oxygen restriction drastically extends the lifespan of progeroid mice, but the effect's mechanism remains a mystery [1]. Can less oxygen be better? Hypoxia is a condition in which an organism or an organ in the body does not receive enough oxygen. However, how much is enough, and whether we are...

A group of Israeli scientists led by Prof. Shai Efrati investigated the effects of hyperbaric oxygen therapy (HBOT) on age-related cognitive decline in healthy older adults, and the results were promising. The brain is the most metabolically active organ in the body, but it has only limited intracellular energy storage [1]. In absence of local...