Tag: Inflammaging

Researchers have devised a method of reducing brain inflammation by creating a long-lasting inhibitor of the inflammatory factor NF-κB. Targeting inflammaging at its roots This study, published in the Nature journal Experimental & Molecular Medicine, begins with a discussion of age-related chronic inflammation (inflammaging) and its contributions to aging. Specifically, the researchers focus on neuroinflammation,...

Reseachers publishing in Antioxidants have combined three antioxidant and anti-inflammatory compounds and tested their effects in human beings. Three complementing choices What is Inflammaging? Chronic Inflammation and AgingOne of the aging processes consists of a chronic, smoldering background of inflammation that researchers call “inflammaging”.Read More The first component the researchers included was AM3, a compound...

In Aging Cell, researchers have published their findings that exosomes, which we have previously reported to extend the lives of mice, also extend the lives of rats. Known to be effective Exosomes, a subset of extracellular vesicles (EVs), can be visualized as messages and packages that cells send to one another. Along with lifespan studies,...

A new study published in Aging Cell has detailed what happens to individual fat cells in white adipose tissue (WAT) as they age. When fat is more than just fat Previous research has described WAT as an organ in its own right, functioning not only as an energy storage source but as a regulator of...

A new preprint from David Sinclair’s lab has discovered that NMN supplementation started in midlife increases median and maximal lifespan in female mice and boosts healthspan in males [1]. NAD and aging Nicotinamide adenine dinucleotide (NAD) is a ubiquitous metabolite that performs several crucial roles. NAD’s oxidized version, NAD+, participates in energy production, facilitates DNA...

In npj Aging, researchers have described how immune cell infiltration in inflammaging can be reduced with an immune-related peptide in a mouse model. Immune cell infiltration What is Inflammaging? Chronic Inflammation and AgingOne of the aging processes consists of a chronic, smoldering background of inflammation that researchers call “inflammaging”.Read More In a previous paper, these...