July 29, 2024
In Aging, a pair of researchers has published a perspective connecting fat (lipid) accumulation and cellular senescence in neurons to Parkinson's disease. α-syn, but not just α-syn Parkinson's disease is characterized by the loss of a specific population of neurons: the dopaminergic neurons in the substantia nigra, a part of the brain that governs movement...
August 08, 2022
A team of researchers publishing in Nature Communications has described nanobodies that can destroy the α-synuclein aggregates that characterize Lewy bodies, which are associated with dementia and Parkinson's disease [1]. What are nanobodies? Traditional antibody therapies, while promising in some studies, are too large to enter cells in order to affect the aggregates there [2]....