September 18, 2019
Cellular senescence, discovered in 1961 by Leonard Hayflick and Paul Moorhead, is a state in which cells no longer perform their functions, instead emitting harmful chemicals that turn other cells senescent. Senescence is primarily caused by telomere shortening and DNA damage, and senescent cells are known to contribute to multiple diseases, such as Alzheimer's, Parkinson's,...
February 06, 2019
February 4th, 2019 saw the Longevity Leaders Conference hosted in Aldersgate, London. I was fortunate enough to have been invited to attend this interesting event, so I thought that today was the ideal time to share some experiences of the conference with you. The conference was quite broad in scope and included people from the...
July 16, 2018
We interviewed Dr. Peter de Keizer, a researcher who is engaged in studying senescent cells and designing therapies to destroy them in order to delay and prevent age-related diseases. Cleara Biotech is currently using his research to develop a senolytic peptide that accomplishes this via interfering with the interactions between p53 and FOXO4. Senescent cells...