Rejuve.AI Launches International Longevity Research Database

by Press release
January 29, 2026

Roatán, Honduras — Rejuve.AI is activating the International Longevity Research Database (IRLDB) through its first real-world study cohort at the Longevity Biomarkers Competition and Summit, taking place February to March 2026 as part of the Infinite Games in Roatán, Honduras.

The IRLDB is being activated through its first registered, consented cohort. Participants enrolled in the Longevity Biomarkers Competition are pre-boarded into the database under a formally registered IRLDB protocol. They contribute standardized baseline and follow-up biomarker data alongside continuous, app-mediated real-world tracking using the Rejuve Longevity App,

This cohort represents an early deployment of Rejuve.AI’s research infrastructure, ahead of a broader public rollout planned as on-chain and scaling components are introduced to support larger study volumes.

In parallel, Infinita City will host the next installment of the JoyScore experiment in collaboration with Longevity Rave, following a pilot conducted at Frontier Tower in December 2025.

A Real-World, App-Enabled Longevity Study

The Longevity Biomarkers Competition functions as the first live application of the IRLDB protocol, demonstrating how longevity research can be conducted in real-world settings while maintaining scientific rigor.

Participants undergo standardized testing at defined timepoints while contributing longitudinal data via the Rejuve App between assessments. Measurements include blood-based biomarkers, epigenetic clocks, metabolomic profiles, wearable-derived physiological data, and structured questionnaires capturing function, behavior, and environment.

This approach enables consistent benchmarking while preserving ecological validity, capturing how individuals actually live, train, and adapt over time. It also provides a structured framework for self-experimentation that prioritizes data quality, participant safety, and informed consent.

Mapping the Signatures of Human Longevity Summit

The competition is preceded by an opening summit on February 7–8, bringing together leading figures in aging research, clinical longevity, and translational science, including Eric Verdin, Andrea Maier, and other international researchers and practitioners, with participation from organizations including XPRIZE, the Buck Institute for Research on Aging, and the Biomarkers of Aging Consortium.

A central focus of the summit is the ongoing debate in the longevity field around healthspan versus lifespan as the primary goal of intervention. Discussions explore the premise that meaningful lifespan extension necessarily implies preserved or improved healthspan, and that regenerative and damage-repair approaches should not extend periods of decline.

Additional themes include how emerging and partially unvalidated therapies are being used in practice, and how clinics, consumers, and researchers can approach such interventions in ways that maximize learning, data sharing, safety, and participant autonomy.

JoyScore Part II and the Exposome

The summit also incorporates the second installment of the JoyScore experiment, led by longevity researcher Tina Woods. JoyScore explores how psychological wellbeing, social connection, and environmental and lifestyle exposures interact with biological aging processes over time.

Attendees of the Infinita Games may opt in to participate, contributing JoyScore data through the Rejuve App. This enables psychosocial and exposomic signals to be analyzed alongside biomarker and functional data within the same research infrastructure.

About Rejuve.AI

Rejuve.AI is a decentralized longevity research network developing open, protocol-driven systems for studying aging, healthspan, and potential rejuvenation through real-world, longitudinal data.

About Infinita City

Infinita City is a longevity-focused innovation environment in Prospera, Roatán, supporting real-world experimentation in health, science, and emerging technologies.

About Longevity Rave

Longevity Rave is a global platform exploring longevity through science, culture, and participatory experiences, including the JoyScore experiment.

We would like to ask you a small favor. We are a non-profit foundation, and unlike some other organizations, we have no shareholders and no products to sell you. All our news and educational content is free for everyone to read, but it does mean that we rely on the help of people like you. Every contribution, no matter if it’s big or small, supports independent journalism and sustains our future.

Yes I will donate❤️