Category: Interviews
How Multivitamins and Minerals Impact Health and Longevity
December 24, 2025
A recent review evaluated studies that included over 5.5 million participants to assess the impact of multivitamin and mineral supplements on different aspects of health [1]. A big market Multivitamin
Bacterium From Frogs Completely Destroys Colon Cancer
December 23, 2025
Scientists in Japan have discovered that multiple strains of bacteria taken from frogs, newts, and lizards can be effective against human colon cancer in a mouse model. One particular microbe
Researchers Find a Potential Target for Hearing Loss
December 23, 2025
In Aging Cell, researchers have identified bone marrow stromal antigen 2 (BST2) as a key protein in age-related hearing loss in a mouse model. Neural myelination is necessary for function
Producing Thymic Factors in the Liver Rejuvenates Immunity
December 22, 2025
A new study proposes a novel approach to fighting immune system decline caused by thymic involution: making the liver produce proteins that support T cell development and function [1]. Bringing
Maximina Yun on the Wonders of the Axolotl
December 19, 2025
Dr. Maximina Yun, principal investigator at Chinese Institutes for Medical Research in Beijing (CIMR), studies some of the most amazing animals in the world: salamanders, a group of amphibians that
A Gene That Changes Function With Aging in Mice
December 18, 2025
In Nature Aging, researchers have discovered how growth differentiation factor 3 (GDF3), a cytokine that increases with aging, is related to more inflammatory macrophages in older animals. Fat and inflammation
Analyzing the Quality of Preclinical Anti-Aging Research
December 17, 2025
Researchers have investigated the reporting quality of preclinical studies’ outcomes in anti-aging research. They analyzed how study quality changed over time, shortcomings in research, and the improvements that can be
Senescence Exacerbated by Mitochondrial RNA Leakage
December 16, 2025
Scientists have investigated a little-known mechanism that fuels cellular senescence: mitochondrial RNA leaking into the cytoplasm. Targeting this mechanism showed promise in a mouse model of fatty liver [1]. The
Targeting a Metabolic Regulator Reduces Fat in Mice
December 15, 2025
In Aging, researchers have described how they removed visceral fat from older male mice by targeting the metabolic regulatory protein CD47. A key regulator of metabolism Visible fat carried around
Molecule From Chocolate Linked to Slower Epigenetic Aging
December 12, 2025
A new observational study spanning two human cohorts has found a link between theobromine, a phytochemical abundant in cocoa, and slower epigenetic aging [1]. A yummy geroprotector? Popular wisdom has
Human Umbilical Cord Blood Metabolites Lengthen Worms’ Lives
December 11, 2025
Comparison of human umbilical cord blood with adult plasma revealed hundreds of metabolites whose abundances were age-dependent. Two different formulas, each a mix of a few metabolites, demonstrated anti-senescence properties
A Year of Rejuvenation Research and Journalism
December 11, 2025
Happy holidays! Winter is in full swing for those of us in the Northern Hemisphere. It is a time for cozy nights by the fire and a great time to
A Key Molecular Link Between Aging and Osteoporosis
December 11, 2025
In Aging Cell, researchers have described how an age-related deficiency in another compound leads the antioxidant FoxO1 to contribute to bone deterioration in osteoporosis by siphoning from a bone-building pathway.
Stem Cell-Derived Vesicles Improve Cognition in Aged Monkeys
December 9, 2025
In a new study, extracellular vesicles (EVs) derived from mesenchymal stem cells (MSCs) improved spatial working memory in rhesus macaques, suggesting a possible reversal of age-related cognitive decline [1]. The
Nasal Tissue Extracellular Vesicles Improve Health in Mice
December 8, 2025
Researchers have discovered that extracellular vesicles (EVs) derived from the nasal mucosa provide significant regenerative benefits to tissues throughout the body, including the brain. A very regenerative tissue Previous work
How Multivitamins and Minerals Impact Health and Longevity
December 24, 2025
A recent review evaluated studies that included over 5.5 million participants to assess the impact of multivitamin and mineral supplements on different aspects of health [1]. A big market Multivitamin and mineral (MVM) supplements are widely used worldwide, and in the United States, around 40% of adults report taking MVMs
Bacterium From Frogs Completely Destroys Colon Cancer
December 23, 2025
Scientists in Japan have discovered that multiple strains of bacteria taken from frogs, newts, and lizards can be effective against human colon cancer in a mouse model. One particular microbe achieved a perfect response rate and survival [1]. Bacteria against cancer Recent research has illuminated the enormous impact of the
Researchers Find a Potential Target for Hearing Loss
December 23, 2025
In Aging Cell, researchers have identified bone marrow stromal antigen 2 (BST2) as a key protein in age-related hearing loss in a mouse model. Neural myelination is necessary for function Demyelination, the loss of neurons’ protective sheaths, is known to be fundamental in multiple serious neurological disorders, including both amyotrophic
Producing Thymic Factors in the Liver Rejuvenates Immunity
December 22, 2025
A new study proposes a novel approach to fighting immune system decline caused by thymic involution: making the liver produce proteins that support T cell development and function [1]. Bringing back the Ts Immunosenescence, the gradual deterioration of the immune system, is a central aspect of aging. Research has tied
Maximina Yun on the Wonders of the Axolotl
December 19, 2025
Dr. Maximina Yun, principal investigator at Chinese Institutes for Medical Research in Beijing (CIMR), studies some of the most amazing animals in the world: salamanders, a group of amphibians that includes newts and species such as the universally loved axolotl. On top of being cute, salamanders possess unparalleled regeneration abilities
A Gene That Changes Function With Aging in Mice
December 18, 2025
In Nature Aging, researchers have discovered how growth differentiation factor 3 (GDF3), a cytokine that increases with aging, is related to more inflammatory macrophages in older animals. Fat and inflammation We have recently reported on a potential treatment for visceral fat, as this kind of fat is known to generate
Analyzing the Quality of Preclinical Anti-Aging Research
December 17, 2025
Researchers have investigated the reporting quality of preclinical studies’ outcomes in anti-aging research. They analyzed how study quality changed over time, shortcomings in research, and the improvements that can be made in the future in order to yield as many valuable insights as possible [1]. The need for quality Aging
Senescence Exacerbated by Mitochondrial RNA Leakage
December 16, 2025
Scientists have investigated a little-known mechanism that fuels cellular senescence: mitochondrial RNA leaking into the cytoplasm. Targeting this mechanism showed promise in a mouse model of fatty liver [1]. The new target The increasing abundance of senescent cells with age has been linked to numerous diseases and is considered a
Targeting a Metabolic Regulator Reduces Fat in Mice
December 15, 2025
In Aging, researchers have described how they removed visceral fat from older male mice by targeting the metabolic regulatory protein CD47. A key regulator of metabolism Visible fat carried around the body is subcutaneous fat. While this kind of fat is obviously not healthy to have in large amounts, it
Molecule From Chocolate Linked to Slower Epigenetic Aging
December 12, 2025
A new observational study spanning two human cohorts has found a link between theobromine, a phytochemical abundant in cocoa, and slower epigenetic aging [1]. A yummy geroprotector? Popular wisdom has it that not many things in life are both healthy and delicious, but according to research, one of them is
Human Umbilical Cord Blood Metabolites Lengthen Worms’ Lives
December 11, 2025
Comparison of human umbilical cord blood with adult plasma revealed hundreds of metabolites whose abundances were age-dependent. Two different formulas, each a mix of a few metabolites, demonstrated anti-senescence properties in cell cultures and model organisms [1]. Young blood has benefits Previous research has provided evidence that surgically connecting the
A Year of Rejuvenation Research and Journalism
December 11, 2025
Happy holidays! Winter is in full swing for those of us in the Northern Hemisphere. It is a time for cozy nights by the fire and a great time to catch up on what has been happening at Lifespan News and LRI. A cultural intelligence platform for effective advocacy We
A Key Molecular Link Between Aging and Osteoporosis
December 11, 2025
In Aging Cell, researchers have described how an age-related deficiency in another compound leads the antioxidant FoxO1 to contribute to bone deterioration in osteoporosis by siphoning from a bone-building pathway. A harmful antioxidant? Because they fight against harmful reactive oxygen species (ROS), antioxidants, both external and internal, are normally viewed
Stem Cell-Derived Vesicles Improve Cognition in Aged Monkeys
December 9, 2025
In a new study, extracellular vesicles (EVs) derived from mesenchymal stem cells (MSCs) improved spatial working memory in rhesus macaques, suggesting a possible reversal of age-related cognitive decline [1]. The “normal” decline Even “healthy” aging (not accompanied by obvious age-related diseases such as dementia) leads to cognitive impairments, particularly in
Nasal Tissue Extracellular Vesicles Improve Health in Mice
December 8, 2025
Researchers have discovered that extracellular vesicles (EVs) derived from the nasal mucosa provide significant regenerative benefits to tissues throughout the body, including the brain. A very regenerative tissue Previous work involving the transection of sizable portions of the nasal mucosa has found that this tissue grows back quickly and without