Month: October 2020

A new study published in Aging has shown that although taking metformin while undergoing resistance training limits muscle growth, it promotes youthful gene expression. The downside As the researchers of this study point out, previous research shows that taking metformin while undergoing physical resistance training (PRT) restricts the development of hypertrophy [1]. While hypertrophy is...

New research published in Stem Cell Research and Therapy has improved the regenerative potential of chondrocytes in vitro. CartilageCartilage tissue is found in various places throughout the human body, including the ears, the nose, between the ribs, and the trachea. While trauma can compromise cartilage in each of these locations, most cartilage problems occur at...

Aging research is still an emerging field, and its emergence has been laden with difficulties. Until recently, the budgets were scarce, the ideas ridiculed, and public involvement nonexistent. The tide is turning, with more private and institutional players eager to spend money and effort on the noble goal of extending human lifespan and healthspan. Still,...

Today, we want to highlight another study that takes us a step closer to getting partial cellular reprogramming to the clinic. Yamanaka Factors - Opportunities for RejuvenationDrs. Takahashi and Yamanaka showed that they could use Oct4, Sox2, Klf4, and c-Myc (OSKM) to reprogram cells back to pluripotent, embryonic stem cells. While this discovery showed that cellular identity...

A new analysis has revealed a core set of genes involved in aging in both humans and mice. Together with a broader set of age-related genes assembled by the study [1], this resource will serve as a launching point for further investigations of the mechanisms behind aging and age-related diseases. The heart of the matter...

The latest research published in the Journal of Tissue Engineering and Regenerative Medicine has reprogrammed pig fibroblast cells into neural progenitor cells.