Lifespan Research Institute

Category: News

Long-term lung disease

Senolytics May Treat Some Long-Term Viral Lung Damage

In Aging Cell, researchers have published their findings that mice exposed to influenza experience long-term consequences that can be partially ameliorated with senolytics. Post-viral syndromes Long before the spread of

Liposome

A New Method of Modifying Stem Cells

Researchers have investigated a never-before-used method of transfecting senescent mesenchymal stem cells (MSCs) and published their results In the Cell journal Molecular Therapy Nucleic Acids. Detergents for gene therapy Altering

Blood vessel cells

A Popular Sweetener Adversely Affects Blood Vessels

A new study has lent more support to previous epidemiological data that ties the popular sugar substitute erythritol to elevated cardiovascular risk [1]. Deceptively sweet Sugar substitutes have been around

Touching DNA

Preventing CRISPR From Causing Senescence

Researchers publishing in Cell Reports Medicine have taken a look at what causes CRISPR/Cas9 gene-editing technology to drive cells senescent and investigated a potential method of preventing it. Breaking and

Gut bacteria close up

How Gut Microbiota Impact Endothelial Cell Senescence

In a recent study that included data from humans, mice, and cell culture experiments, researchers demonstrated that gut microbes and their metabolites can profoundly influence the senescence of endothelial cells.

Editorial

Springtime for the Longevity Industry

If you are in the Northern Hemisphere, then spring is well underway and the weather is warming up. This is the season of renewal and growth. With that in mind,

Neurons

New Insights Into How Neural Stem Cells Age

Researchers publishing in Aging Cell have used single-cell transcriptomics to discover new insights into how neural stem cells (NSCs) change with aging. Adults do generate neurons The adult brain does

Long-term lung disease

Senolytics May Treat Some Long-Term Viral Lung Damage

In Aging Cell, researchers have published their findings that mice exposed to influenza experience long-term consequences that can be partially ameliorated with senolytics. Post-viral syndromes Long before the spread of the SARS-CoV-2 virus that causes COVID-19, it had been well-established that viral lung diseases such as

Vitalist Bay

Longevity Policy, Advocacy in the Spotlight at Vitalist Bay

Just several years ago, longevity conferences were few and far between. Today, there’s no shortage of them. Happening regularly around the globe, they foster scientific debate and showcase geroscience advances to the world while energetically discussing longevity biotech and regulations. However, one important subfield, working with

Glial cell

Engineering Microglia to Deliver an Anti-Alzheimer’s Drug

In Cell Stem Cell, researchers have described how genetically engineered microglia can be used to deliver therapeutic proteins to the brain. The blood-brain barrier Delivering therapeutic compounds to the brain has a concern that is absent for other organs: the blood-brain barrier (BBB), which retains strict

Older woman's brain

Longer Reproductive Spans Linked to Younger Brains in Women

Analysis of over a thousand postmenopausal women suggests that women with longer reproductive spans, earlier first period (menarche), and later menopause experience slower brain aging [1]. Linking sex hormones to brain health The female reproductive system fails to work properly much earlier than other systems in

Older people with financial problems

Financial Behavior Might Help Diagnose Dementia Early

By analyzing a large UK dataset, scientists have identified various financial behaviors that might point to dementia years before it leads to loss of financial capacity [1]. The money trail Alzheimer’s disease and related dementias remain a particularly hard nut for scientists to crack. One commonly

Liposome

A New Method of Modifying Stem Cells

Researchers have investigated a never-before-used method of transfecting senescent mesenchymal stem cells (MSCs) and published their results In the Cell journal Molecular Therapy Nucleic Acids. Detergents for gene therapy Altering the genetics of a living person is much trickier than altering them in cells in a

Blood vessel cells

A Popular Sweetener Adversely Affects Blood Vessels

A new study has lent more support to previous epidemiological data that ties the popular sugar substitute erythritol to elevated cardiovascular risk [1]. Deceptively sweet Sugar substitutes have been around for decades, and while some people have reported decreases in weight and blood glucose, a growing

Touching DNA

Preventing CRISPR From Causing Senescence

Researchers publishing in Cell Reports Medicine have taken a look at what causes CRISPR/Cas9 gene-editing technology to drive cells senescent and investigated a potential method of preventing it. Breaking and repairing DNA Genetic engineering of living cells through CRISPR/Cas9 technology requires three things to occur. The

Gut bacteria close up

How Gut Microbiota Impact Endothelial Cell Senescence

In a recent study that included data from humans, mice, and cell culture experiments, researchers demonstrated that gut microbes and their metabolites can profoundly influence the senescence of endothelial cells. They also explored the molecular processes underlying these changes [1]. Senescence in the blood vessels Endothelial

Cancer vaccine

New Study Could Pave the Way for Better Cancer Vaccines

Scientists have found that only about 1% of presented tumor antigens come from oncogenic mutations. The remaining 99%, previously overlooked, may offer better treatment targets [1]. Going after mutations Cancer arises from a series of mutations that drive abnormal cellular behaviors, such as runaway proliferation. Cancerous

Boyang Wang Interview

Boyang Wang on Targeting Underfunded Longevity Projects

In this interview, Boyang Wang of Immortal Dragons discusses the kinds of projects he wants to fund, ways in which the industry can be encouraged to develop, relationships between the East and West in longevity research and development, and what got him involved in longevity. Hello,

Assisting elderly

Younger Cohorts Show Less Dementia at the Same Age

While the overall prevalence of dementia might be rising due to population aging, a study has found that today’s older people seem to be less prone to dementia than in the past [1]. Are we having more dementia or less? While the robust rise in average

Editorial

Springtime for the Longevity Industry

If you are in the Northern Hemisphere, then spring is well underway and the weather is warming up. This is the season of renewal and growth. With that in mind, let’s take a look at what the Lifespan and LRI team has been up to. Top

Neurons

New Insights Into How Neural Stem Cells Age

Researchers publishing in Aging Cell have used single-cell transcriptomics to discover new insights into how neural stem cells (NSCs) change with aging. Adults do generate neurons The adult brain does generate new neurons [1], particularly in the hippocampus, the part of the brain responsible for memory

Rejuve.ai Interview

Rejuve.AI: Just Another App or a Longevity Research Network?

On its website, Rejuve.AI, a company co-founded by its dynamic CEO, Jasmine Smith, and a renowned AI researcher, Ben Goertzel, promises a lot of things: to “democratize longevity, globally,” to enable you to “take control of your data, and harness its earning potential,” and to “unite