Lifespan Research Institute

Category: News

Rejuvenation Roundup March

Rejuvenation Roundup March 2020

Today might be April Fool’s Day, but COVID-19 is no joke, aging isn’t either, and the combination of the two definitely isn’t – and the people attempting to reverse the

Dividing cells

Success in Reprogramming a Supercentenarian’s Cells

Researchers from AgeX Therapeutics and other organizations have proved the feasibility of reprogramming banked cells derived from a supercentenarian. Their discovery portends exciting new possibilities for aging research. What is

Brain inflammation

Our Immune Cells Damage Our Brains During Aging

New research suggests that the very immune cells that protect our brain can eventually start attacking it due to chronic systemic inflammation, something that is typically present in older people.

Diabetes meter

Towards a Possible Solution to Diabetes

A team of researchers led by Dr. Jeffrey Millman at Washington University may be a step closer to a potential solution to diabetes, according to the results of a new

Organ chip

Automating Drug Testing With Human Organ Chips

Researchers from the Universities of Harvard and Tel Aviv have succeeded in linking up to 10 “organs-on-a-chip” via an analog of human vasculature. The invention allows for in vitro testing

Rejuvenation Roundup February

Rejuvenation Roundup February 2020

Several leaps have been made this February: Leap Year’s Day, leaps in rejuvenation biotechnology development, and a leap of our own in bringing our two websites together into one. If

Interview with Lewis Gruber

Lewis Gruber – Senotherapeutics

At the recent Longevity Therapeutics Conference in San Francisco, we had the chance to interview Lewis Gruber of SIWA Therapeutics and discuss his company’s senotherapeutic approach to cancer and senescent

Macrophage

Macrophages Become Scars in the Heart

A paper published in Nature Communications reveals that, rather than just summoning fibroblasts, inflammatory macrophages themselves form fibrous tissue that is the basis of scars. The dual role of macrophages

Rejuvenation Roundup January

Rejuvenation Roundup January 2020

2020 has been a common year to define the beginning of “the future”, so now’s a great time to discover just how close real biotechnology has come to popular expectations.

Intestinal villi

Enzyme Prevents Frailty and Intestinal Barrier Decline

A new study suggests that the enzyme intestinal alkaline phosphatase (IAP) appears to help to prevent age-related loss of intestinal barrier integrity in mice, fruit flies, and potentially humans. Improving intestinal barrier integrity There can now be little doubt that the decline of intestinal barrier integrity

Rejuvenation Roundup March

Rejuvenation Roundup March 2020

Today might be April Fool’s Day, but COVID-19 is no joke, aging isn’t either, and the combination of the two definitely isn’t – and the people attempting to reverse the hallmarks of aging in order to give us longer, healthier lives aren’t messing around. Here’s what’s

Dividing cells

Success in Reprogramming a Supercentenarian’s Cells

Researchers from AgeX Therapeutics and other organizations have proved the feasibility of reprogramming banked cells derived from a supercentenarian. Their discovery portends exciting new possibilities for aging research. What is cellular reprogramming? Cellular reprogramming is the process of reverting mature, specialized cells into induced pluripotent stem

Brain inflammation

Our Immune Cells Damage Our Brains During Aging

New research suggests that the very immune cells that protect our brain can eventually start attacking it due to chronic systemic inflammation, something that is typically present in older people. The blood-brain barrier The blood-brain barrier (BBB) surrounds most of the blood vessels in the brain

Diabetes meter

Towards a Possible Solution to Diabetes

A team of researchers led by Dr. Jeffrey Millman at Washington University may be a step closer to a potential solution to diabetes, according to the results of a new study in which replacement beta cells were given to mice. What is diabetes? Diabetes is a

Organ chip

Automating Drug Testing With Human Organ Chips

Researchers from the Universities of Harvard and Tel Aviv have succeeded in linking up to 10 “organs-on-a-chip” via an analog of human vasculature. The invention allows for in vitro testing of drug toxicity and action, taking us one step closer to automated clinical trials and the

Rejuvenation Roundup February

Rejuvenation Roundup February 2020

Several leaps have been made this February: Leap Year’s Day, leaps in rejuvenation biotechnology development, and a leap of our own in bringing our two websites together into one. If you want to help us and the world of rejuvenation biotechnology leap into the public consciousness

Smiley face

What Do Smiley Faces Have to Do With Cancer Research?

DNA origami, a nano-scale technique used to make very tiny smiley faces out of DNA, is becoming increasingly valuable for drug delivery and other applications, paving the way for true nanomedicine. What is DNA origami? Ever since Richard Feynman famously proclaimed in his seminal 1959 talk

Interview with Lewis Gruber

Lewis Gruber – Senotherapeutics

At the recent Longevity Therapeutics Conference in San Francisco, we had the chance to interview Lewis Gruber of SIWA Therapeutics and discuss his company’s senotherapeutic approach to cancer and senescent cells. He was accompanied by his wife, Misty, who is the CFO of SIWA. Many of

Interview with Hanadie Yousef

Hanadie Yousef – Embryonic Proteins for Tissue Regeneration

At the recent Longevity Therapeutics Conference in San Francisco, we had the chance to interview Hanadie Yousef, the co-founder and CEO of Juvena Therapeutics. Juvena is isolating proteins from embryonic stem cells that promote tissue regrowth. Can you describe in more detail Juvena’s approach to developing

Optimism

Life Expectancy Could Rise Significantly in the Near Future

Let’s face it, getting older sucks, and not because of all the extra candles on the birthday cake. Getting cake and presents every year is great, but the loss of health and independence isn’t a particularly good birthday present. (Wow, what’d I get this year? Just

Macrophage

Macrophages Become Scars in the Heart

A paper published in Nature Communications reveals that, rather than just summoning fibroblasts, inflammatory macrophages themselves form fibrous tissue that is the basis of scars. The dual role of macrophages Macrophages perform two critical roles in the immune system. After an injury, M1 macrophages spur local

Irina and Michael Conboy

Irina & Michael Conboy – Making Old Blood Young Again

We were at the recent Longevity Therapeutics Conference in San Francisco, and we had the opportunity to interview Irina and Michael Conboy from UC Berkeley about their pioneering work on blood factors and aging. Irina is a member of our Scientific Advisory Board, and the Conboys’

Mitochondria

Refining the Allotopic Expression of Mitochondrial Genes

Researchers from SENS Research Foundation, including Matthew O’Connor and Amutha Boominathan, have published a new study showing how codons play an important role in getting copies of mitochondrial genes placed in the cellular nucleus to express themselves correctly [1]. A possible solution to mitochondrial diseases Mitochondrial

Rejuvenation Roundup January

Rejuvenation Roundup January 2020

2020 has been a common year to define the beginning of “the future”, so now’s a great time to discover just how close real biotechnology has come to popular expectations. To kick off the first month of the new year, we have plenty of research to