Category: News
Removing Senescent Cells Improves Heart Health
February 11, 2019
Researchers at Newcastle University have shown that clearing out senescent cardiac muscle cells from the hearts of aged mice restores heart health. It seems that not a month goes by
Developing Better Senescent Cell Biomarkers
February 8, 2019
In aging research, there has long been a need for better biomarkers that can detect and confirm the presence of senescent cells. This has become particularly urgent in recent years
Longevity Leaders Conference Report
February 6, 2019
February 4th, 2019 saw the Longevity Leaders Conference hosted in Aldersgate, London. I was fortunate enough to have been invited to attend this interesting event, so I thought that today
Fool’s Mate
February 5, 2019
(Death is in the “cryonics patients” section of his collection, a temporary exhibition, in the company of a young woman. They are sitting at a chess table, surrounded by the
Sebastian Aguiar – Aging Research and Investment
February 4, 2019
Today, we have an interview with Longevity Investor Network member Sebastian Aguiar, who has kindly shared some of his thoughts and motivations with us. Sebastian Aguiar is a Venture Fellow at
Rejuvenation Roundup January 2019
February 1, 2019
Welcome to the first Rejuvenation Roundup of the new year! There is quite a bit of news to go through and upcoming events to look forward to, so get comfortable
New Aging Clock Could Predict Your Future Lifespan
January 31, 2019
A new aging clock developed by Professor Steve Horvath and his research team takes measuring your biological age a step further and can accurately predict your future lifespan. The epigenetic
The American Public Increasingly Desires Life Extension
January 28, 2019
While medical schools have had the idea that aging should be brought under medical control for over a century, the explicit desire to greatly extend one’s life remained rare –
The Gut Microbiome of Healthy, Long-Lived People
January 23, 2019
A new study has outlined the age-related changes of the gut microbiome, showing a correlation between the microbiome’s composition and overall health. The gut microbiome The microbiome describes a varied
UNITY Biotechnologies Selects a New Senolytic Candidate
January 14, 2019
Another senolytic drug candidate has entered development at Unity Biotechnologies. The purpose of senolytics is to clear the body of harmful senescent cells, which accumulate with age and encourage age-related
NAD+ Enters Cells via Newly Discovered Pathway
January 9, 2019
A new study published in Nature Metabolism finally reveals the answer to how NMN enters the cell in order to become NAD+ and that it does not need to be
Human Pilot Study Results for Senolytics Published
January 7, 2019
The results from a human pilot study that focused on treating idiopathic pulmonary fibrosis with senescent cell-clearing drugs has been published. The drugs target aged and damaged cells, which are
An Interview with Dr. Kris Verburgh, M.D.
January 4, 2019
At the Fourth Eurosymposium on Healthy Ageing, which was held in Brussels last November, Elena and I met Dr. Kris Verburgh, a medical doctor who is especially interested in biogerontology
An Interview with Dr. Leonid Peshkin
January 3, 2019
Determined but not complacent, grounded but hopeful, Dr. Leonid Peshkin is one of the scientists working on understanding aging so that it may one day be treated like we treat
Fisetin May be a Low-Hanging Fruit for Aging
December 26, 2018
There has been considerable interest in fisetin recently, especially for its potential as a senolytic, which clears away dysfunctional senescent cells that accumulate with aging. Researchers believe that fisetin may
Removing Senescent Cells Improves Heart Health
February 11, 2019
Researchers at Newcastle University have shown that clearing out senescent cardiac muscle cells from the hearts of aged mice restores heart health. It seems that not a month goes by without a new study showing that senolytics, drugs that remove aged and damaged cells from the
Developing Better Senescent Cell Biomarkers
February 8, 2019
In aging research, there has long been a need for better biomarkers that can detect and confirm the presence of senescent cells. This has become particularly urgent in recent years due to the meteoric rise of the senescent cell-clearing therapies known as senolytics. Traditional ways of
Longevity Leaders Conference Report
February 6, 2019
February 4th, 2019 saw the Longevity Leaders Conference hosted in Aldersgate, London. I was fortunate enough to have been invited to attend this interesting event, so I thought that today was the ideal time to share some experiences of the conference with you. The conference was
Fool’s Mate
February 5, 2019
(Death is in the “cryonics patients” section of his collection, a temporary exhibition, in the company of a young woman. They are sitting at a chess table, surrounded by the frozen display cases of the rest of the patients.) — That was a real nasty move,
Sebastian Aguiar – Aging Research and Investment
February 4, 2019
Today, we have an interview with Longevity Investor Network member Sebastian Aguiar, who has kindly shared some of his thoughts and motivations with us. Sebastian Aguiar is a Venture Fellow at Apollo Ventures, an aging-focused venture capital fund and company builder that invests across Europe and the
Rejuvenation Roundup January 2019
February 1, 2019
Welcome to the first Rejuvenation Roundup of the new year! There is quite a bit of news to go through and upcoming events to look forward to, so get comfortable and let’s get started. LEAF News Team and Activities Announcing Ending Age-Related Diseases 2019 Early last
New Aging Clock Could Predict Your Future Lifespan
January 31, 2019
A new aging clock developed by Professor Steve Horvath and his research team takes measuring your biological age a step further and can accurately predict your future lifespan. The epigenetic clock As we age, our DNA experiences chemical changes called DNA methylation (DNAm); these changes are
The American Public Increasingly Desires Life Extension
January 28, 2019
While medical schools have had the idea that aging should be brought under medical control for over a century, the explicit desire to greatly extend one’s life remained rare – until very recently. A new study by YouGov, a market intelligence company that researches multiple topics,
The Gut Microbiome of Healthy, Long-Lived People
January 23, 2019
A new study has outlined the age-related changes of the gut microbiome, showing a correlation between the microbiome’s composition and overall health. The gut microbiome The microbiome describes a varied community of bacteria, archaea, eukarya, and viruses that inhabit our gut. The four bacterial phyla of
UNITY Biotechnologies Selects a New Senolytic Candidate
January 14, 2019
Another senolytic drug candidate has entered development at Unity Biotechnologies. The purpose of senolytics is to clear the body of harmful senescent cells, which accumulate with age and encourage age-related diseases to develop. A new treatment for age-related diseases of the eye Recently, UNITY Biotechnologies announced
NAD+ Enters Cells via Newly Discovered Pathway
January 9, 2019
A new study published in Nature Metabolism finally reveals the answer to how NMN enters the cell in order to become NAD+ and that it does not need to be converted into NR to do so. In the last few years, there has been considerable interest
Human Pilot Study Results for Senolytics Published
January 7, 2019
The results from a human pilot study that focused on treating idiopathic pulmonary fibrosis with senescent cell-clearing drugs has been published. The drugs target aged and damaged cells, which are thought to be a reason we age and get sick, and remove them from the body.
An Interview with Dr. Kris Verburgh, M.D.
January 4, 2019
At the Fourth Eurosymposium on Healthy Ageing, which was held in Brussels last November, Elena and I met Dr. Kris Verburgh, a medical doctor who is especially interested in biogerontology and the potential of this field of study to turn medicine on its head. Dr. Verburgh
An Interview with Dr. Leonid Peshkin
January 3, 2019
Determined but not complacent, grounded but hopeful, Dr. Leonid Peshkin is one of the scientists working on understanding aging so that it may one day be treated like we treat any other ailment. As he revealed in an interview with the Boston Globe in mid-2018, the
Fisetin May be a Low-Hanging Fruit for Aging
December 26, 2018
There has been considerable interest in fisetin recently, especially for its potential as a senolytic, which clears away dysfunctional senescent cells that accumulate with aging. Researchers believe that fisetin may be useful in increasing the healthy period of life known as healthspan. What is Fisetin? Fisetin