Lifespan Research Institute

Category: News

NAD+ and Aging With Mike Bonkowski

Today, we have an interview with Dr. Michael Bonkowski, an expert on NAD+ biology and aging from the David Sinclair Lab, Harvard Medical School. Michael Bonkowski aims to advance our

The Status Quo of Aging

One of the reasons why the idea of rejuvenating people isn’t all that easy to sell is that it challenges the status quo. For good or bad, we’re used to

From Within Your Own Failing Shell

Some time ago, I noticed a stock photo of an old lady seeing her geriatrician, who was a much younger woman. Nothing special was happening in the picture, which showed

An Interview With David Gobel

David Gobel is an inventor, philanthropist, futurist, and passionate rejuvenation advocate and supporter; he’s known for co-founding Methuselah Foundation with Dr. Aubrey de Grey and for proposing the intriguing concept

DNA Replication Can Happen Without ORC1

According to a study conducted by Hollings Cancer Center scientists at the Medical University of South Carolina, DNA replication in murine cells is possible even in the absence of origin

Rejuvenation Roundup August 2018

We hope August has treated you well—it certainly did so for life extension, as this has been another month full of great news for the field. Don’t be upset with

An Interview With Didier Coeurnelle

As you might remember, we have recently posted about the Longevity Film Competition, an initiative by HEALES, ILA, and the SENS Research Foundation that encourages supporters of healthy life extension

NAD+ and Aging With Mike Bonkowski

Today, we have an interview with Dr. Michael Bonkowski, an expert on NAD+ biology and aging from the David Sinclair Lab, Harvard Medical School. Michael Bonkowski aims to advance our understanding of the links between metabolism, aging, and age-associated diseases. He has published 35 peer-reviewed journal

The Status Quo of Aging

One of the reasons why the idea of rejuvenating people isn’t all that easy to sell is that it challenges the status quo. For good or bad, we’re used to the fact that our health goes south on us as time goes by, ultimately killing us

Paywall: The Business of Scholarship Documentary in English and Russian

Today, we want to let you know that the documentary Paywall: The Business of Scholarship is now available in both English and Russian. This is a documentary exploring the crisis in scientific journal publication and the excessive fees that some publishers charge to access knowledge. Holding

From Within Your Own Failing Shell

Some time ago, I noticed a stock photo of an old lady seeing her geriatrician, who was a much younger woman. Nothing special was happening in the picture, which showed just two people talking; however, it made me wonder what it must feel like to be

Administering Gene Therapy Without Triggering Immune Response

Scientists at Stanford University School of Medicine managed to administer effective gene therapy in mice without triggering an autoimmune reaction. The research, led by Dr. Peggy Ho, Ph.D., was published in the Proceedings of the National Academy of Sciences [1]. Study abstract In gene therapy for

A Review of Cellular Senescence and Senolytics

Today, we want to point out a new publication that dives into the world of senolytics, which are drugs or therapies that seek and destroy harmful non-dividing cells that resist the programmed cell death known as apoptosis. These cells linger in the body, and, as we

NAD+ Repletion Shows Potential Against Aging

Science is advancing rapidly, and the field of aging research is no exception. Our understanding of aging has grown a great deal in the last decade, and we are now reaching the point at which the first therapies that target aging are starting to arrive. Unlike

An Interview With David Gobel

David Gobel is an inventor, philanthropist, futurist, and passionate rejuvenation advocate and supporter; he’s known for co-founding Methuselah Foundation with Dr. Aubrey de Grey and for proposing the intriguing concept of “longevity escape velocity”, but his achievements and successes extend far beyond that. David has kindly

DNA Replication Can Happen Without ORC1

According to a study conducted by Hollings Cancer Center scientists at the Medical University of South Carolina, DNA replication in murine cells is possible even in the absence of origin recognition complex 1 (ORC1), a protein encoded by the homonymous gene that was previously thought to

Rejuvenation Roundup August 2018

We hope August has treated you well—it certainly did so for life extension, as this has been another month full of great news for the field. Don’t be upset with the departure of summer and the arrival of autumn, because little by little, we’re getting close

Getting Aging Classified as a Disease – Daria Khaltourina

We are pleased to report that lobbyists have made more progress towards classifying aging as a disease. The World Health Organization (WHO) has implemented the extension code ‘Ageing-related’ (XT9T) in the latest version of the International Classification of Diseases (ICD). The inclusion of the new code

Alexandra Elbakyan is the creator of Sci-Hub.

Alexandra Elbakyan – The System is Holding Back Scientific Progress

Today, we have an interview with Sci-Hub creator Alexandra Elbakyan, who is committed to the free flow of scientific knowledge and is challenging the unfair journal system, which charges outrageous fees to view scientific publications. Hiding scientific knowledge behind paywalls Around 70% of scientific publications are

Telomerase Gene Therapy Does Not Increase Cancer Risk

Researchers have demonstrated that telomerase gene therapy does not increase the risk of cancer, even in strains of mice that are particularly susceptible to cancer [1]. A tale of telomeres Short telomeres trigger cellular senescence and are thought to be one of the primary hallmarks of

Dr. Irina Conboy Joins the LEAF Scientific Advisory Board

We are growing fast as an organization thanks to the support of the community, particularly our monthly patrons, the Lifespan Heroes. We are delighted to announce that another respected scientist, Dr. Irina Conboy, has joined our scientific advisory board and will be providing us with expert

An Interview With Didier Coeurnelle

As you might remember, we have recently posted about the Longevity Film Competition, an initiative by HEALES, ILA, and the SENS Research Foundation that encourages supporters of healthy life extension to produce a short film to popularize the subject. Didier Coeurnelle is a jurist and the