Lifespan Research Institute

Category: News

The Good Sides of Aging?

Sometimes, and especially in articles aimed at mitigating people’s fear of aging, it is said that aging doesn’t come just with downsides, such as frailty and diseases, but also with

Juvenescence: Investing in the Age of Longevity

Jim Mellon and Al Chalabi are back with another successful venture into the world of science investment. Following their acclaimed 2012 book “Cracking the code”, whose spotlight was on the

Investing in the Age of Longevity

Today, we are pleased to announce the imminent arrival of Jim Mellon and Al Chalabi’s new book Juvenescence, which covers the field of rejuvenation biotechnology. The book focuses on technologies

MitoSENS Update August 2017

The following is an update from MitoSENS scientist Dr. Matthew “Oki” O’Connor: Hi, everyone! Long time, no update – my fault! As you all saw, our manuscript that was supported

False Positives in Senescent Cell Detection

Macrophages with markers of cellular senescence may not be senescent  Researchers commonly determine the presence of senescent cells through the use of the p16ink4a (p16) and β-galactosidase biomarkers. Senescent cells

The Good Sides of Aging?

Sometimes, and especially in articles aimed at mitigating people’s fear of aging, it is said that aging doesn’t come just with downsides, such as frailty and diseases, but also with upsides—for example, wisdom and a long life experience. It is often subtly implied that these two

Juvenescence: Investing in the Age of Longevity

Jim Mellon and Al Chalabi are back with another successful venture into the world of science investment. Following their acclaimed 2012 book “Cracking the code”, whose spotlight was on the life sciences industry, Juvenescence takes us on a compelling journey through the dawning market of longevity

Review of Juvenescence: Investing in the Age of Longevity

Only two years ago, when I launched my advocacy website Rejuvenaction, I didn’t think I would read a book like Juvenescence so soon; yet, the topic of rejuvenation biotechnologies has already become mainstream enough to lead investors of the calibre of Jim Mellon and Al Chalabi

Forget ‘live fast, die young’ – do the opposite instead

So far, the only intervention that is known to consistently increase lifespan across multiple species is caloric restriction (CR). Caloric restriction is known to increase lifespan in the majority of mouse strains tested [1] and many other species. The effects of CR have even been shown

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Open Consultation of the WHO on Research Priorities for Healthy Aging

Very recently, the World Health Organization, which is essentially the United Nations’ agency for coordinating international health-related efforts, has launched The Global Online Consultation on Research Priority Setting for Healthy Aging. A corresponding survey is available on the WHO website and can be filled until September

Investing in the Age of Longevity

Today, we are pleased to announce the imminent arrival of Jim Mellon and Al Chalabi’s new book Juvenescence, which covers the field of rejuvenation biotechnology. The book focuses on technologies that will soon arrive, therapies that may increase healthy lifespan, and guidance for investors. The book

Reviewing Stem Cell Therapies for Osteoporosis

Osteoporosis is a crippling condition provoked by an imbalance between the creation of new bone tissue and the destruction of the old, which becomes worse as we age. What causes osteoporosis to develop and progress? Osteoporosis is the failure of tissue maintenance in the bones, causing

MitoSENS Update August 2017

The following is an update from MitoSENS scientist Dr. Matthew “Oki” O’Connor: Hi, everyone! Long time, no update – my fault! As you all saw, our manuscript that was supported by Lifespan.io donors was published last fall. Dr. Boominathan and I have been presenting our results

False Positives in Senescent Cell Detection

Macrophages with markers of cellular senescence may not be senescent  Researchers commonly determine the presence of senescent cells through the use of the p16ink4a (p16) and β-galactosidase biomarkers. Senescent cells are known to exhibit both of these biomarkers, but it seems that they are not the

How Misfolded Proteins Cause Age-related Diseases

Coming from a fusion of the words ‘protein’ (a molecule that a cell uses as a machine or scaffolding) and ‘stasis’ (meaning to keep the same), the term ‘proteostasis’ can essentially be simplified into “Each function reliant on proteins is running as it should. There are

Restoring Youthful Plasticity in the Brains of Old Mice

As we age, our brains lose their flexibility; this, in turn, affects our ability to learn, to remember things and to adapt to new situations. The classic example is of older people who are stuck in a rut and unable to change how they think. Some

Senolytics as a Potential Treatment for Lung Fibrosis

Today, we have a new study in which researchers focus on pulmonary fibrosis and the role of cellular senescence. What is pulmonary fibrosis? Pulmonary fibrosis causes scarring of lung tissue, which results in the progressive loss of lung function over time. When the disease’s origin is

George Church – Turn Back Time to End Age-related Diseases

Many of you will likely already know who Professor George Church is, and that he is an important and senior member of the research community engaged in treating the aging processes to prevent or reverse age-related diseases, not to mention all kinds of other applications for