Category: News
George Church – Turn Back Time to End Age-related Diseases
August 1, 2017
Many of you will likely already know who Professor George Church is, and that he is an important and senior member of the research community engaged in treating the aging
New Study Suggests Previous Concerns about CRISPR Safety are Questionable
July 26, 2017
Gene editing aims to make precise changes to the target DNA whilst avoiding altering other parts of the DNA. The objective of this is to remove undesirable genetic traits and
The real cost of life extension advocacy
July 20, 2017
There is a persistent view that life extension advocacy is something that does not require any investment and can be done in your spare time. Fundraising for overhead expenses is
Reprogramming Cells to Seek and Destroy Brain Cancer
July 6, 2017
A new type of cell that can seek and destroy brain cancer and then dispose of themselves has just been successfully tested in mice. The cells are able to home
Adjusting Macrophages to Heal Peripheral Nerve Injury
July 1, 2017
Researchers studying peripheral nerve damage have adjusted the behaviour of macrophages to facilitate healing. [1] What is peripheral nerve injury? The peripheral nerves are located outside of the brain and
Alexandra Elbakyan – Science Should Be Open to All, Not Behind Paywalls
June 27, 2017
A few days ago, at the international exhibition Geek Picnic 2017 in Moscow, LEAF director Elena Milova had the opportunity to talk with the founder of Sci-Hub, Alexandra Elbakyan. The
Dr. Jose Luis Cordeiro – Cryonics and Rejuvenation Biotechnology
June 9, 2017
During the recent International Longevity and Cryopreservation Summit in Madrid, LEAF Board member Elena Milova had the opportunity to speak with Dr. Jose Luis Cordeiro, new fellow of the World Academy
Boosting Autophagy to Treat Atherosclerosis
June 8, 2017
Today, we decided that it was a good time to take a look at a new study that demonstrates that increasing autophagy is a good approach to slowing aging and
Friday June 9th 13:00 EST/18:00 UK “How to Promote Longevity?”
June 7, 2017
LEAF/Lifespan.io is teaming up with the Major Mouse Testing Program (MMTP) for a special longevity panel with Dr. Alexandra Stolzing, Dr. Aubrey de Grey, Dr. Oliver Medvedik and a number
The Need for Better Aging Biomarkers
May 27, 2017
As human life expectancy has increased throughout the 20th and 21st centuries, this has led to a steady increase in the population of older people. With that increase has come
Treating Diseases with a Protein Missile System
May 26, 2017
Researchers at the University of Dundee have shown that it is possible to target and destroy specific proteins within cells using a new directed protein missile system. This is very
How Population Aging First Became an International Concern
April 25, 2017
Today, we bring you an interview with Dr. Marvin Formosa, director of the International Institute on Ageing of the United Nations, Malta (INIA). First, let’s find out how the issue
Error CORRECTion for CRISPR
April 23, 2017
The CRISPR system (Clustered Regularly Interspaced Short Palindromic Repeats) has exploded onto the biotech sector as a relatively simple, highly efficient, and fast method for precisely introducing breaks into genomic
Dr. Alex Zhavoronkov – A.I. Versus Aging
April 18, 2017
The battle against aging is not going to be an easy one, and it will likely require the most refined tools modern science has to offer. Among them, artificial intelligence
Removing Aging Cells With a New Class of Senolytic Drug
April 15, 2017
The new research work on senolytic drugs by Baar et al. uses a rationally designed molecule that selectively targets senescent cells in vivo, both in an accelerated aging mouse model, and
George Church – Turn Back Time to End Age-related Diseases
August 1, 2017
Many of you will likely already know who Professor George Church is, and that he is an important and senior member of the research community engaged in treating the aging processes to prevent or reverse age-related diseases, not to mention all kinds of other applications for
New Study Suggests Previous Concerns about CRISPR Safety are Questionable
July 26, 2017
Gene editing aims to make precise changes to the target DNA whilst avoiding altering other parts of the DNA. The objective of this is to remove undesirable genetic traits and introduce desirable changes in both plants and animals. For example, it could be used to make
The real cost of life extension advocacy
July 20, 2017
There is a persistent view that life extension advocacy is something that does not require any investment and can be done in your spare time. Fundraising for overhead expenses is like the proverbial elephant in the room: it is hard not to notice it is there,
Reprogramming Cells to Seek and Destroy Brain Cancer
July 6, 2017
A new type of cell that can seek and destroy brain cancer and then dispose of themselves has just been successfully tested in mice. The cells are able to home in on brain tumors and reduce them to between 2 to 5% of their original size[1].
Adjusting Macrophages to Heal Peripheral Nerve Injury
July 1, 2017
Researchers studying peripheral nerve damage have adjusted the behaviour of macrophages to facilitate healing. [1] What is peripheral nerve injury? The peripheral nerves are located outside of the brain and spinal cord. They carry signals to the muscles to initiate movement as well as transporting sensory
Alexandra Elbakyan – Science Should Be Open to All, Not Behind Paywalls
June 27, 2017
A few days ago, at the international exhibition Geek Picnic 2017 in Moscow, LEAF director Elena Milova had the opportunity to talk with the founder of Sci-Hub, Alexandra Elbakyan. The Sci-Hub website is devoted to providing scientists, students, and researchers with free access to scientific publications
Dr. Jose Luis Cordeiro – Cryonics and Rejuvenation Biotechnology
June 9, 2017
During the recent International Longevity and Cryopreservation Summit in Madrid, LEAF Board member Elena Milova had the opportunity to speak with Dr. Jose Luis Cordeiro, new fellow of the World Academy of Art and Science (WAAS) and long-term proponent of innovation technologies in many fields. Jose shared his
Boosting Autophagy to Treat Atherosclerosis
June 8, 2017
Today, we decided that it was a good time to take a look at a new study that demonstrates that increasing autophagy is a good approach to slowing aging and could be the foundation for a variety of therapies to treat age-related diseases. What is Autophagy?
Friday June 9th 13:00 EST/18:00 UK “How to Promote Longevity?”
June 7, 2017
LEAF/Lifespan.io is teaming up with the Major Mouse Testing Program (MMTP) for a special longevity panel with Dr. Alexandra Stolzing, Dr. Aubrey de Grey, Dr. Oliver Medvedik and a number of guests. The MMTP will be streaming the panel live to their Facebook page and we
The Need for Better Aging Biomarkers
May 27, 2017
As human life expectancy has increased throughout the 20th and 21st centuries, this has led to a steady increase in the population of older people. With that increase has come the rise of age-related diseases and disabilities. As a result, it is becoming ever more important
Treating Diseases with a Protein Missile System
May 26, 2017
Researchers at the University of Dundee have shown that it is possible to target and destroy specific proteins within cells using a new directed protein missile system. This is very interesting, as it raises the possibility of targeting aberrant proteins present in diseases that currently have
How Population Aging First Became an International Concern
April 25, 2017
Today, we bring you an interview with Dr. Marvin Formosa, director of the International Institute on Ageing of the United Nations, Malta (INIA). First, let’s find out how the issue of population aging was first introduced into the agenda of the United Nations and why the
Error CORRECTion for CRISPR
April 23, 2017
The CRISPR system (Clustered Regularly Interspaced Short Palindromic Repeats) has exploded onto the biotech sector as a relatively simple, highly efficient, and fast method for precisely introducing breaks into genomic loci [1-2]. The realization that it is a prokaryotic acquired immune system, although less often mentioned,
Dr. Alex Zhavoronkov – A.I. Versus Aging
April 18, 2017
The battle against aging is not going to be an easy one, and it will likely require the most refined tools modern science has to offer. Among them, artificial intelligence may be one of the most promising and is being extensively used by biogerontology researchers such
Removing Aging Cells With a New Class of Senolytic Drug
April 15, 2017
The new research work on senolytic drugs by Baar et al. uses a rationally designed molecule that selectively targets senescent cells in vivo, both in an accelerated aging mouse model, and in normally aged mice as well, with few if any side effects [1]. Senolytics are a