Lifespan Research Institute

Category: News

Gene editing

Nuclear Expression of a Mitochondrial Gene in Mice

Scientists from the Longevity Research Institute (LRI), which was formed by the merger of SENS Research Foundation and Lifespan.io, have achieved expression of an essential mitochondrial gene in the nucleus

Skeletal muscle

Fragmented Mitochondria Linked to Muscle Weakness

In a study published in Aging Cell, researchers have outlined a relationship between mitochondrial fragmentation in skeletal muscle and the loss of strength with age. Broken power plants As its

Computer healthcare analysis

Can AI Predict Your Death?

Once confined to the realms of science fiction or relatively crude internet death calculators, AI-driven predictions about longevity are inching closer to reality. Questions about the accuracy and value of

Rejuvenation Roundup November 2024

Rejuvenation Roundup November 2024

While the United States has just celebrated a holiday that opposes caloric restriction, researchers there and around the world continue to discover the effects of it and other interventions against

Menopause

Building an Atlas of Human Ovarian Aging

The researchers of a Nature Aging paper used multi-omics approaches to investigate cellular, molecular, and genetic drivers of human ovarian aging [1]. An early decline A decline in ovarian function

GSA 2024

The Best Talks of GSA 2024

Today, we bring you a selection of presentations from the annual conference organized by the Gerontological Society of America. Most of our savvy readers, if asked to name the biggest

MSCs

Finding Cells That Send Signals Against Arthritis

In Aging, researchers have reported that deriving extracellular vesicles from mesenchymal stromal cells (MSCs) in fat tissue has beneficial effects in models of osteoarthritis. Which source to use? Earlier this

Older man exercising

How Exercise Preserves Function in Motor Nerves

In Aging Cell, researchers have described the specific cell types that give exercise protective effects against motor nerve degeneration. A different level of back problems With aging, the prevalence of

Vitalism

Announcing Vitalist Bay, a Pop-Up City in the Bay Area

A unique project is set to go live next spring in the Bay Area. Organized by the Vitalism Foundation, it promises to be one of the largest longevity-related events ever. They’re popping up! Since the pop-up city of Zuzalu took the longevity community by storm in

Gene editing

Nuclear Expression of a Mitochondrial Gene in Mice

Scientists from the Longevity Research Institute (LRI), which was formed by the merger of SENS Research Foundation and Lifespan.io, have achieved expression of an essential mitochondrial gene in the nucleus and proper functioning of the protein. This could pave the way for curing diseases caused by

Skeletal muscle

Fragmented Mitochondria Linked to Muscle Weakness

In a study published in Aging Cell, researchers have outlined a relationship between mitochondrial fragmentation in skeletal muscle and the loss of strength with age. Broken power plants As its authors point out, this is far from the first study to link mitochondrial dysfunction and aging

Robot doctor

AI Outperforms AI-Assisted Doctors in Diagnostic Reasoning

In a new study, ChatGPT 4.0 achieved significantly better diagnostic scores when evaluating complex cases than either unassisted human physicians or physicians who consulted the chatbot [1]. Bad news for human doctors? For millions of people, chatbots powered by large language models (LLMs) have quickly become

Computer healthcare analysis

Can AI Predict Your Death?

Once confined to the realms of science fiction or relatively crude internet death calculators, AI-driven predictions about longevity are inching closer to reality. Questions about the accuracy and value of these forecasts remain. In recent years, researchers and companies around the globe have been pursuing answers

Oranges and Grapes

Resveratrol, Vitamin C Drop Oxidative Stress After Menopause

In a randomized, controlled trial published in Nutrients, researchers tested supplementation with resveratrol, vitamin C, and a combination of both. They learned that all of the treatments had a similar positive impact on oxidative stress in postmenopausal women [1]. Menopausal transition Around the world, a significant

Mehmood Khan Interview

Mehmood Khan on Aging Policy and Collaboration

I first met Dr. Mehmood Khan in 2022 at the inaugural Longevity Summit Dublin, where organizers Aubrey de Grey and Martin O’Dea made a bold decision to include policy and advocacy discussions alongside the traditional focus on longevity research. Like many others in the audience, I

Three supplements

A Clinical Trial of a Three-Part Treatment for Inflammaging

Reseachers publishing in Antioxidants have combined three antioxidant and anti-inflammatory compounds and tested their effects in human beings. Three complementing choices The first component the researchers included was AM3, a compound that is core to the Inmunoferon supplement and is an immunomodulator that has been found

Rejuvenation Roundup November 2024

Rejuvenation Roundup November 2024

While the United States has just celebrated a holiday that opposes caloric restriction, researchers there and around the world continue to discover the effects of it and other interventions against aging. Let’s see what’s been done in November. Interviews Rozalyn Anderson Explains Caloric Restriction: At the

Menopause

Building an Atlas of Human Ovarian Aging

The researchers of a Nature Aging paper used multi-omics approaches to investigate cellular, molecular, and genetic drivers of human ovarian aging [1]. An early decline A decline in ovarian function occurs before a similar decline in other organs. Already in their mid-to-late thirties, women can experience

GSA 2024

The Best Talks of GSA 2024

Today, we bring you a selection of presentations from the annual conference organized by the Gerontological Society of America. Most of our savvy readers, if asked to name the biggest gerontology conference, would probably go with the venerable ARDD in Copenhagen or the new favorite, Hevolution

MSCs

Finding Cells That Send Signals Against Arthritis

In Aging, researchers have reported that deriving extracellular vesicles from mesenchymal stromal cells (MSCs) in fat tissue has beneficial effects in models of osteoarthritis. Which source to use? Earlier this month, we wrote about how small extracellular vesicles derived from embryonic cells (ESC-sEVs) alleviate arthritis in

Older man exercising

How Exercise Preserves Function in Motor Nerves

In Aging Cell, researchers have described the specific cell types that give exercise protective effects against motor nerve degeneration. A different level of back problems With aging, the prevalence of nerves connecting to muscle tissue dwindles, a phenomenon known as denervation [1]. This has been linked

Diverse diet

Dietary Diversity Is Associated With Delayed Aging

An analysis of data from over twenty thousand people has indicated that greater dietary diversity is associated with slower biological aging [1]. Your health is what you eat Good dietary habits are linked to many health benefits, and different diets were previously reported to impact the

Growing neuron

Intranasal Spray Alleviates Early Alzheimer’s in Mice

A novel therapy based on induced neuronal stem cells shows promise in a mouse model of Alzheimer’s disease – and it can be administered intranasally [1]. Who needs cells? Stem cell therapies have made great strides in recent decades. They have been successfully employed against numerous