Category: News
The Impact of a Human Breast Milk Probiotic on Sarcopenia
January 15, 2025
A recent study linked probiotic-induced gut microbiome and metabolite changes to improved muscle functioning in older sarcopenia patients [1]. Sarcopenia and the gut Sarcopenia is an age-related condition. People with
A Gut Metabolite Reduces Senescence and Inflammation
January 14, 2025
In a preprint study, scientists from Lifespan Research Institute and the Buck Institute for Research on Aging have published their findings that Urolithin A, a molecule that has garnered a
Cyclarity Launches Human Trial for Atherosclerosis
January 13, 2025
Cyclarity Therapeutics, a biotechnology company based at the Buck Institute in California, has launched its first human clinical trial. Its primary candidate cyclodextrin drug, UDP-003, focuses on 7-ketocholesterol, an oxidized
Intermittent Fasting Improves Coordination in Mice
January 13, 2025
Researchers have discovered that intermittent fasting increases myelin in aged mice, leading to better neural function and coordination. Crucial proteins and a well-known intervention Normally, neuronal axons are coated in
Precision Targeting of Senescent Cells
January 9, 2025
In a journal called Small, researchers have described a new targeting mechanism for delivering senolytic compounds where they need to go. Finding the right nanoparticle This paper begins with a
Receiving Caloric Restriction Benefits Without Practicing It
January 8, 2025
In a new study, researchers have found that lithocholic acid, a metabolite found in the serum of calorically restricted mice, can mimic the effects of caloric restriction [1]. Restricting calories
Drinking and Dying: Alcohol as a Risk Factor for Cancer
January 7, 2025
A new advisory by the US Surgeon General highlights a topic that – as the document itself notes – has been flying mostly under the public’s radar: the relationship between
A Potential Gene Therapy for Hearing Loss
January 6, 2025
In JCI Insight, researchers have explored the possibility of using gene therapy to restore a crucial protein and repair hearing loss. Hearing and its failure In mammals, afferent neurons, which
Keeping Stem Cells Healthy and Young
January 2, 2025
A team of researchers has outlined a new approach that uses mRNA to prevent senescence and strengthen mesenchymal stem cells (MSCs) against aging before they are transplanted into patients. Stem
Rejuvenation Roundup December 2024
January 2, 2025
The holiday season is over and the new year is here, and we’re back to discussing the one gift that matters the most: biological rejuvenation. Let’s see what’s been done
Another Year of Longevity Advocacy and Journalism
December 23, 2024
The nights are the longest of the year, the holidays are drawing near, and we are back with a festive edition of the Lifespan.io editorial. This time, we bring you
The Best Talks From Longevity Summit 2024
December 23, 2024
Earlier this month, for the third year in a row, the famed Buck Institute for Research on Aging hosted the Longevity Summit. This two-day event was organized by Longevity Global,
How Cellular Reprogramming Affects Mitochondrial Dysfunction
December 19, 2024
Creating induced pluripotent stem cells (iPSCs) causes mutant mitochondrial populations to change, and researchers have investigated this phenomenon more thoroughly. Easy to mutate Being outside of the protection of the
Lower Rates of Epigenetic Aging in Olympic Champions
December 18, 2024
A recent investigation into Hungarian Olympic champions suggests slower epigenetic aging and differences in gene methylation patterns between champions and non-champions [1]. Exercising your way to longevity Exercise seems to
A Senolytic Approach to Faster Wound Healing
December 17, 2024
Researchers have published in Aging their findings that a senolytic compound accelerates wound healing in aged mice when it is administered before the wound occurs. A well-known laboratory senolytic While
The Impact of a Human Breast Milk Probiotic on Sarcopenia
January 15, 2025
A recent study linked probiotic-induced gut microbiome and metabolite changes to improved muscle functioning in older sarcopenia patients [1]. Sarcopenia and the gut Sarcopenia is an age-related condition. People with sarcopenia suffer from a reduction in muscle mass, strength, and function, leading to a decreased quality
A Gut Metabolite Reduces Senescence and Inflammation
January 14, 2025
In a preprint study, scientists from Lifespan Research Institute and the Buck Institute for Research on Aging have published their findings that Urolithin A, a molecule that has garnered a lot of attention in the longevity field, potently reduces senescence-related markers in human fibroblasts [1]. Senolytic
Cyclarity Launches Human Trial for Atherosclerosis
January 13, 2025
Cyclarity Therapeutics, a biotechnology company based at the Buck Institute in California, has launched its first human clinical trial. Its primary candidate cyclodextrin drug, UDP-003, focuses on 7-ketocholesterol, an oxidized cholesterol variant that builds up in cells as we age. Atherosclerosis involves the accumulation of plaque
Intermittent Fasting Improves Coordination in Mice
January 13, 2025
Researchers have discovered that intermittent fasting increases myelin in aged mice, leading to better neural function and coordination. Crucial proteins and a well-known intervention Normally, neuronal axons are coated in a protein sheath made of myelin, which is necessary for their proper function [1]. Myelination is
Precision Targeting of Senescent Cells
January 9, 2025
In a journal called Small, researchers have described a new targeting mechanism for delivering senolytic compounds where they need to go. Finding the right nanoparticle This paper begins with a discussion of the well-known features of cellular senescence and laments that, despite all the work done
Receiving Caloric Restriction Benefits Without Practicing It
January 8, 2025
In a new study, researchers have found that lithocholic acid, a metabolite found in the serum of calorically restricted mice, can mimic the effects of caloric restriction [1]. Restricting calories to live longer Caloric restriction without malnutrition improves healthspan and extended lifespan in multiple model organisms
Drinking and Dying: Alcohol as a Risk Factor for Cancer
January 7, 2025
A new advisory by the US Surgeon General highlights a topic that – as the document itself notes – has been flying mostly under the public’s radar: the relationship between alcohol consumption and cancer. While most people are aware of smoking and obesity being risk factors
A Potential Gene Therapy for Hearing Loss
January 6, 2025
In JCI Insight, researchers have explored the possibility of using gene therapy to restore a crucial protein and repair hearing loss. Hearing and its failure In mammals, afferent neurons, which originate from the inner ear, transform received stimuli (sound waves) into electrical signals [1]. This process
Keeping Stem Cells Healthy and Young
January 2, 2025
A team of researchers has outlined a new approach that uses mRNA to prevent senescence and strengthen mesenchymal stem cells (MSCs) against aging before they are transplanted into patients. Stem cells go bad before they can be used The researchers introduce this study by focusing on
Rejuvenation Roundup December 2024
January 2, 2025
The holiday season is over and the new year is here, and we’re back to discussing the one gift that matters the most: biological rejuvenation. Let’s see what’s been done in December. LEAF News Another Year of Longevity Advocacy and Journalism: The nights are the longest
Another Year of Longevity Advocacy and Journalism
December 23, 2024
The nights are the longest of the year, the holidays are drawing near, and we are back with a festive edition of the Lifespan.io editorial. This time, we bring you some of this year’s highlights and talk about what the future holds for our content. Lifespan.io
The Best Talks From Longevity Summit 2024
December 23, 2024
Earlier this month, for the third year in a row, the famed Buck Institute for Research on Aging hosted the Longevity Summit. This two-day event was organized by Longevity Global, a community of longevity researchers, investors, and enthusiasts, and its founder Dr. Christin Glorioso. While not
How Cellular Reprogramming Affects Mitochondrial Dysfunction
December 19, 2024
Creating induced pluripotent stem cells (iPSCs) causes mutant mitochondrial populations to change, and researchers have investigated this phenomenon more thoroughly. Easy to mutate Being outside of the protection of the nucleus, mitochondria DNA (mtDNA) mutates at anywhere from 10 to 100 times the rate of nuclear
Lower Rates of Epigenetic Aging in Olympic Champions
December 18, 2024
A recent investigation into Hungarian Olympic champions suggests slower epigenetic aging and differences in gene methylation patterns between champions and non-champions [1]. Exercising your way to longevity Exercise seems to be the best lifestyle factor to slow aging and alleviates many aging-associated diseases and molecular changes.
A Senolytic Approach to Faster Wound Healing
December 17, 2024
Researchers have published in Aging their findings that a senolytic compound accelerates wound healing in aged mice when it is administered before the wound occurs. A well-known laboratory senolytic While some senescent cells have been found to have a beneficial effect on wound healing [1], the