Category: News
Heart Organoids Flown to Space Show Signs of Dysfunction
October 15, 2024
Scientists have found that human heart tissue is harmed by even a short stint in orbit. This might have implications for future space travel [1]. Fly me to the Moon
The Chemical Reasons Why Visceral Fat Is Dangerous
October 14, 2024
In Aging Cell, researchers have described the chemical ways in which excessive visceral fat causes oxidative stress and cellular senescence. Visceral fat is metabolically active Metabolic syndrome, a host of
Have We Maxed Out on Life Expectancy Gains?
October 11, 2024
A new study has suggested that radical life extension is all but impossible in this century [1], and it has made waves among people interested in living longer. Out of
Exosomes Break Rat Lifespan Record
October 10, 2024
In Aging Cell, researchers have published their findings that exosomes, which we have previously reported to extend the lives of mice, also extend the lives of rats. Known to be
Astragalus Supplement Lengthens Telomeres in the Middle-Aged
October 9, 2024
Treating middle-aged people for six months with a supplement combination that included astragalus, a plant used in traditional Chinese medicine, positively impacted their telomeres [1]. Preventing the shortening Telomeres are
Cryptic Exons for Targeting Neurodegenerative Disease
October 8, 2024
Amyotrophic lateral sclerosis (ALS) only affects a fraction of cells and must be treated with high specificity. Scientists have achieved that by targeting mRNA sites associated with the disease [1].
Senescent Macrophages: A Unique Target
October 7, 2024
In Aging, researchers have published a new study on a tool meant for analyzing macrophage senescence along with differences between inflammaging and regular inflammation. Macrophages are driven to senescence Previous
Fall Is Here, but It’s Full Steam Ahead for Lifespan.io
October 7, 2024
For those of us living in the Northern Hemisphere, the summer days are gone and the cooler days of fall have arrived. While it’s time to ditch the beachwear for
UK Citizens Are Healthier Than Americans, but Don’t Feel So
October 4, 2024
A new study shows that in midlife, United States citizens are less healthy than their British counterparts. The latter, however, smoke more and rate their health worse [1]. I’ll show
Exercise Intensity, Duration, and Amount All Matter
October 3, 2024
In the European Journal of Protective Cardiology, researchers have published evidence that the intensity of exercise is somewhat more important than volume in reducing all-cause mortality risk, although both have
mTOR and SGLT-2 Inhibitors Impact Age-Related Processes
October 2, 2024
The authors of a recent review propose that there may be positive synergistic effects from combining mTOR inhibitors and sodium-glucose co-transporter-2 (SGLT-2) inhibitors [1]. Inhibition of two molecules is better
Boosting Autophagy in Astrocytes Might Help Cure Alzheimer’s
October 1, 2024
With Alzheimer’s disease, most of the focus has been on neurons. A new study’s researchers suggest boosting the process of cellular junk removal in astrocytes, brain cells that perform maintenance
Rejuvenation Roundup September 2024
October 1, 2024
This past month, we’ve covered plenty of research news and information about conferences, but now we have some news of our own. Here’s what’s been happening in the rejuvenation biotechnology
Lifespan.io and SENS Research Foundation Unite
October 1, 2024
October 1, 2024 – Lifespan.io (Lifespan Extension Advocacy Foundation) and SENS Research Foundation are excited to announce the completion of their merger, forming a new 501(c)(3) non-profit: Lifespan Research Institute.
How Lifesaving Treatments Can Cause Long-Term Harm
September 30, 2024
A research paper published in Aging explored a link between breast cancer, hematopoietic cell transplants (HCTs), an increase in physical frailty, and cellular senescence. Treatment comes at a cost HCTs
Heart Organoids Flown to Space Show Signs of Dysfunction
October 15, 2024
Scientists have found that human heart tissue is harmed by even a short stint in orbit. This might have implications for future space travel [1]. Fly me to the Moon Space exploration is cool, but the human body was obviously not made for it. All its
The Chemical Reasons Why Visceral Fat Is Dangerous
October 14, 2024
In Aging Cell, researchers have described the chemical ways in which excessive visceral fat causes oxidative stress and cellular senescence. Visceral fat is metabolically active Metabolic syndrome, a host of intertwined disorders that include obesity and cholesterol imbalance, is known to have multiple harmful effects that
Have We Maxed Out on Life Expectancy Gains?
October 11, 2024
A new study has suggested that radical life extension is all but impossible in this century [1], and it has made waves among people interested in living longer. Out of steam? A paper titled “Implausibility of radical life extension in humans in the twenty-first century” was
Exosomes Break Rat Lifespan Record
October 10, 2024
In Aging Cell, researchers have published their findings that exosomes, which we have previously reported to extend the lives of mice, also extend the lives of rats. Known to be effective Exosomes, a subset of extracellular vesicles (EVs), can be visualized as messages and packages that
Astragalus Supplement Lengthens Telomeres in the Middle-Aged
October 9, 2024
Treating middle-aged people for six months with a supplement combination that included astragalus, a plant used in traditional Chinese medicine, positively impacted their telomeres [1]. Preventing the shortening Telomeres are like shoelace aglets, forming protective caps at the ends of DNA strands. They are made of
Cryptic Exons for Targeting Neurodegenerative Disease
October 8, 2024
Amyotrophic lateral sclerosis (ALS) only affects a fraction of cells and must be treated with high specificity. Scientists have achieved that by targeting mRNA sites associated with the disease [1]. Cryptic behavior ALS is a neurodegenerative disease in which age is a major factor. While it
Senescent Macrophages: A Unique Target
October 7, 2024
In Aging, researchers have published a new study on a tool meant for analyzing macrophage senescence along with differences between inflammaging and regular inflammation. Macrophages are driven to senescence Previous work has found that excessive senescent cells are uniquely harmful to macrophages, recruiting them into senescence
Fall Is Here, but It’s Full Steam Ahead for Lifespan.io
October 7, 2024
For those of us living in the Northern Hemisphere, the summer days are gone and the cooler days of fall have arrived. While it’s time to ditch the beachwear for chunky sweaters and a hot chocolate by the fire, things have been heating up in the
UK Citizens Are Healthier Than Americans, but Don’t Feel So
October 4, 2024
A new study shows that in midlife, United States citizens are less healthy than their British counterparts. The latter, however, smoke more and rate their health worse [1]. I’ll show you my health if you show me yours It is well-known that despite the US being
Exercise Intensity, Duration, and Amount All Matter
October 3, 2024
In the European Journal of Protective Cardiology, researchers have published evidence that the intensity of exercise is somewhat more important than volume in reducing all-cause mortality risk, although both have significant correlations. The questions of how long and how much Conventional wisdom had maintained that exercise
mTOR and SGLT-2 Inhibitors Impact Age-Related Processes
October 2, 2024
The authors of a recent review propose that there may be positive synergistic effects from combining mTOR inhibitors and sodium-glucose co-transporter-2 (SGLT-2) inhibitors [1]. Inhibition of two molecules is better than one mTOR is a well-known molecule in aging research. Inhibition of mTOR has been shown
Boosting Autophagy in Astrocytes Might Help Cure Alzheimer’s
October 1, 2024
With Alzheimer’s disease, most of the focus has been on neurons. A new study’s researchers suggest boosting the process of cellular junk removal in astrocytes, brain cells that perform maintenance tasks, as a new pathway [1]. Looking at a different cell type Accumulation of amyloid beta,
Rejuvenation Roundup September 2024
October 1, 2024
This past month, we’ve covered plenty of research news and information about conferences, but now we have some news of our own. Here’s what’s been happening in the rejuvenation biotechnology world. LEAF News Lifespan.io and SENS Research Foundation Unite to Launch a New Powerhouse in Aging
Lifespan.io and SENS Research Foundation Unite
October 1, 2024
October 1, 2024 – Lifespan.io (Lifespan Extension Advocacy Foundation) and SENS Research Foundation are excited to announce the completion of their merger, forming a new 501(c)(3) non-profit: Lifespan Research Institute. Lifespan Research Institute (“LRI”) will develop, promote, and ensure widespread access to regenerative medicine solutions targeting
How Lifesaving Treatments Can Cause Long-Term Harm
September 30, 2024
A research paper published in Aging explored a link between breast cancer, hematopoietic cell transplants (HCTs), an increase in physical frailty, and cellular senescence. Treatment comes at a cost HCTs and breast cancer treatment are lifesaving procedures. However, chemotherapy in breast cancer sharply increases p16INK4a, a