Category: News
Targeting Senescent Cells by Their Surface Markers
September 5, 2024
New research in Aging Cell has suggested that targeting senescent cells based on their surface proteins (surfaceome) may be effective in dealing with them. Focusing on what’s easiest to target
I Dined with Bryan Johnson and Didn’t Die
September 5, 2024
Anxious about being late and distrustful of LA’s afternoon traffic, I got to my destination quite a few minutes early and found myself in a quiet middle-class neighborhood. The house
Keto Diets May Help Cognitive Function in Alzheimer’s
September 4, 2024
The results of 10 independently conducted clinical trials suggest that ketogenic diets have a positive impact on the cognitive function of Alzheimer’s disease patients [1]. Keto instead of a pill?
Combination Therapy Works Against Pancreatic Cancer in Mice
September 3, 2024
In a new study, a multi-prong treatment combined with a clever delivery method has shown promise against one of the deadliest cancers [1]. Lethal and barely treatable Pancreatic ductal adenocarcinoma
Caffeic Acid Variant May Suppress Bone Deterioration
September 2, 2024
In Aging, researchers have described how a derivative of caffeic acid inhibits osteoclasts, the cells that break down bone. A modification of a tested compound We have recently published new
Rejuvenation Roundup August 2024
September 2, 2024
Summer’s at its end, but rejuvenation biotechnology is still heating up, with researchers discovering ways of vastly improving mouse lifespan and conducting a recruitment drive for young scientists. Here’s how
Some Cells Age Much Faster Than Others
August 30, 2024
In Stem Cell Reports, researchers have described how cell subpopulations and division affect the results of epigenetic clocks. Good, but never perfect As these researchers note, epigenetic clocks have had
Skin Aging and Cellular Mobility at the Protein Level
August 29, 2024
In Aging, researchers have described how the changing production of skin cells’ proteins is a core part of their age-related decline. Understanding why skin cells lose their function In healthy
NNMT Inhibitor Improves Muscle Function in Aged Mice
August 28, 2024
A recent paper has reported on improving muscle function in aged mice through combined treatment of exercise and the inhibition of NNMT, an enzyme involved in NAD+ metabolism [1]. Age-related
Weekend-Oriented Physical Activity Superior for Brain Health
August 27, 2024
According to a new study, “weekend warriors”, people who have most of their physical activity over one or two days a week, enjoy the most robust risk reduction for several
Why Bone Destruction Is Accelerated with Aging
August 26, 2024
Researchers have described a relationship between the NAD+ regulator CD38, mitochondrial function, and the gradual destruction of bone in Aging Cell. Inflammation up, bone mass down It is well known
Manuka Honey Effective Against Breast Cancer in Mice
August 23, 2024
UCLA scientists have shown that Manuka, an exclusive honey variety, can quench estrogen receptor-positive breast cancer in vitro and in vivo [1]. Honey, kill that cancer Breast cancer remains the
A Phase 2 Clinical Trial for Hair Loss
August 22, 2024
Los Angeles-based Pelage Pharmaceuticals has just announced a Phase 2a clinical trial for the treatment of androgenetic alopecia, also known as pattern baldness. It is thought that up to 50%
High-Intensity Interval Training Improves Cognition
August 21, 2024
Cognitive decline is one of the risks associated with getting older, but new research suggests there may be a way to fight back. A new study suggests that high-intensity interval
Peter Diamandis: “Stay Healthy, Anti-Aging Tech is Coming”
August 20, 2024
To many people, Peter Diamandis needs no introduction, and to the rest, it’s going to be a long one. To put it as concisely as possible, Peter is a serial
Targeting Senescent Cells by Their Surface Markers
September 5, 2024
New research in Aging Cell has suggested that targeting senescent cells based on their surface proteins (surfaceome) may be effective in dealing with them. Focusing on what’s easiest to target Senescence and the SASP have well-known markers, such as p16, p21, and the well-known SA-β-gal [1].
I Dined with Bryan Johnson and Didn’t Die
September 5, 2024
Anxious about being late and distrustful of LA’s afternoon traffic, I got to my destination quite a few minutes early and found myself in a quiet middle-class neighborhood. The house I was looking for did stand out from the rest but rather modestly so. A week
Keto Diets May Help Cognitive Function in Alzheimer’s
September 4, 2024
The results of 10 independently conducted clinical trials suggest that ketogenic diets have a positive impact on the cognitive function of Alzheimer’s disease patients [1]. Keto instead of a pill? Despite extensive research, there is stilll no effective treatment for Alzheimer’s disease. Therefore, approaches that aim
Combination Therapy Works Against Pancreatic Cancer in Mice
September 3, 2024
In a new study, a multi-prong treatment combined with a clever delivery method has shown promise against one of the deadliest cancers [1]. Lethal and barely treatable Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest types of cancer. It is rarely diagnosed early and very
Caffeic Acid Variant May Suppress Bone Deterioration
September 2, 2024
In Aging, researchers have described how a derivative of caffeic acid inhibits osteoclasts, the cells that break down bone. A modification of a tested compound We have recently published new information on what triggers the imbalance between bone-destroying osteoclasts and bone-building osteoblasts. This is a well-known
Rejuvenation Roundup August 2024
September 2, 2024
Summer’s at its end, but rejuvenation biotechnology is still heating up, with researchers discovering ways of vastly improving mouse lifespan and conducting a recruitment drive for young scientists. Here’s how the field was advanced in August. Interviews Michael Antonov: from Oculus to Longevity Biotech: After Oculus
Some Cells Age Much Faster Than Others
August 30, 2024
In Stem Cell Reports, researchers have described how cell subpopulations and division affect the results of epigenetic clocks. Good, but never perfect As these researchers note, epigenetic clocks have had successes in analyzing the impact of things that impact biological age, such as the effects of
Skin Aging and Cellular Mobility at the Protein Level
August 29, 2024
In Aging, researchers have described how the changing production of skin cells’ proteins is a core part of their age-related decline. Understanding why skin cells lose their function In healthy skin, dermal fibroblasts produce the proteins needed to maintain the extracellular matrix (ECM), the network of
NNMT Inhibitor Improves Muscle Function in Aged Mice
August 28, 2024
A recent paper has reported on improving muscle function in aged mice through combined treatment of exercise and the inhibition of NNMT, an enzyme involved in NAD+ metabolism [1]. Age-related muscle loss Muscle loss is a common problem in the aging population. Studies estimate that “after
Weekend-Oriented Physical Activity Superior for Brain Health
August 27, 2024
According to a new study, “weekend warriors”, people who have most of their physical activity over one or two days a week, enjoy the most robust risk reduction for several brain health-related conditions [1]. Couch potato, except on weekends Exercise is universally necessary to stay healthy
Why Bone Destruction Is Accelerated with Aging
August 26, 2024
Researchers have described a relationship between the NAD+ regulator CD38, mitochondrial function, and the gradual destruction of bone in Aging Cell. Inflammation up, bone mass down It is well known that CD38, an enzyme that takes away NAD+, increases with age. The gradual depletion of this
Manuka Honey Effective Against Breast Cancer in Mice
August 23, 2024
UCLA scientists have shown that Manuka, an exclusive honey variety, can quench estrogen receptor-positive breast cancer in vitro and in vivo [1]. Honey, kill that cancer Breast cancer remains the deadliest type of cancer in women, claiming more than 40 thousand victims a year in the
A Phase 2 Clinical Trial for Hair Loss
August 22, 2024
Los Angeles-based Pelage Pharmaceuticals has just announced a Phase 2a clinical trial for the treatment of androgenetic alopecia, also known as pattern baldness. It is thought that up to 50% of men experience hair loss as a result of pattern baldness by age 50. In this
High-Intensity Interval Training Improves Cognition
August 21, 2024
Cognitive decline is one of the risks associated with getting older, but new research suggests there may be a way to fight back. A new study suggests that high-intensity interval training improves spatial learning and maintains brain volume and connectivity [1]. Shrinking aging brain One of
Peter Diamandis: “Stay Healthy, Anti-Aging Tech is Coming”
August 20, 2024
To many people, Peter Diamandis needs no introduction, and to the rest, it’s going to be a long one. To put it as concisely as possible, Peter is a serial entrepreneur and investor in several fields, from commercial space flight to longevity biotech; a visionary speaker