Category: News
Rejuvenation Roundup July 2024
August 1, 2024
Entirely new approaches with surprisingly good results have been recently discovered and published in July’s papers. Here’s what the research world has revealed this month. LEAF News Interviews Longevity Biotech
Very Old People Have Healthy Gut Bacteria
July 31, 2024
The authors of a recent review investigated what is known about gut microbiota in centenarians and how gut microbes can help people achieve extreme longevity [1]. What makes centenarians special?
A Key Pathway for Sarcopenia Reversal
July 30, 2024
In Aging Cell, researchers have published a paper on a cellular energy source that appears to be a key signaling molecule in sarcopenia. A little-explored molecule Sarcopenia, a condition that
Senescence May Play a Significant Role in Parkinson’s
July 29, 2024
In Aging, a pair of researchers has published a perspective connecting fat (lipid) accumulation and cellular senescence in neurons to Parkinson’s disease. α-syn, but not just α-syn Parkinson’s disease is
Surprising Effects of Regular Fasting in Model Organisms
July 28, 2024
Research published in Aging Cell has revealed that a nematode species commonly used for aging research lives much longer on an alternate-day fasting regimen, but only when it is administered
Cellular Reprogramming Improves Cognition in Aged Rats
July 26, 2024
Scientists have shown that prolonged, continuous expression of reprogramming factors counters cognitive decline in old rats and probably decreases their epigenetic age [1]. Reprogramming and cognitive function Cellular reprogramming, the
Exploring Senescence in Tendon Function
July 25, 2024
In Aging Cell, researchers have published new data on the relationship between senescence and the extracellular matrix in the tendons of older people. Easy to injure, hard to heal The
A Switch to Whole Food Diets Benefits Elderly People
July 24, 2024
New research demonstrated how transitioning from a typical Western diet composed of processed foods to a whole-food diet improved cardiometabolic health and body composition and impacted gut microbiome metabolites in
Antinuclear Antibody Shows Promise Against Cancer
July 23, 2024
Scientists have developed a conjugate of a drug and a nucleus-targeting antibody that can attack multiple types of cancer cells without targeting a particular antigen [1]. The anti-nuclear missile Antinuclear
Exploring How Stiffness Promotes Osteoarthritis
July 22, 2024
In iScience, researchers have explained how physical mechanics can alter mitochondrial function in a way that leads to osteoarthritis. When simple physics affects biology Previous work has pinpointed abnormal mechanical
Late-Life Treatment Increases Mouse Lifespan by 25%
July 19, 2024
A new mouse study has found that both germline knockout and late-life inhibition of the pro-inflammatory cytokine IL-11 lead to comparable and powerful healthspan and lifespan extension [1]. The inflammatory
Discovering Why an Inflammatory Compound Inhibits Cancer
July 18, 2024
In Aging Cell, researchers have published their findings into why the inflammatory factor IL-6 inhibits cancerous tumors when generated inside the cell. IL-6 affects both senescence and cancer proliferation One
Probiotics Have Positive Cognitive Effects in Trial
July 17, 2024
A clinical trial has found that consuming a multi-species probiotic formulation positively impacts mental well-being and improves cognitive functions [1]. Gut-brain crosstalk The gut microbiome is a gathering of microorganisms
Longevity Biotech Fellowship: Road To A Post-Aging Society
July 16, 2024
The Longevity Biotech Fellowship is one of the most interesting longevity-related initiatives in the last couple of years. Co-founded by Mark Hamalainen and Nathan Cheng, both well-known figures in the
Mixed Results in Probiotic Trial Against Inflammaging
July 15, 2024
Researchers publishing in Probiotics and Antimicrobial Proteins have published the results of a clinical trial on the effects of a probiotic on inflammaging in older people. The gut and systemic
Rejuvenation Roundup July 2024
August 1, 2024
Entirely new approaches with surprisingly good results have been recently discovered and published in July’s papers. Here’s what the research world has revealed this month. LEAF News Interviews Longevity Biotech Fellowship: Road To A Post-Aging Society: The Longevity Biotech Fellowship is one of the most interesting
Very Old People Have Healthy Gut Bacteria
July 31, 2024
The authors of a recent review investigated what is known about gut microbiota in centenarians and how gut microbes can help people achieve extreme longevity [1]. What makes centenarians special? One way of investigating what gives people longevity and health in older ages is to study
A Key Pathway for Sarcopenia Reversal
July 30, 2024
In Aging Cell, researchers have published a paper on a cellular energy source that appears to be a key signaling molecule in sarcopenia. A little-explored molecule Sarcopenia, a condition that increases with aging, reduces muscle mass in older people, and leads to a decreased quality of
Senescence May Play a Significant Role in Parkinson’s
July 29, 2024
In Aging, a pair of researchers has published a perspective connecting fat (lipid) accumulation and cellular senescence in neurons to Parkinson’s disease. α-syn, but not just α-syn Parkinson’s disease is characterized by the loss of a specific population of neurons: the dopaminergic neurons in the substantia
Surprising Effects of Regular Fasting in Model Organisms
July 28, 2024
Research published in Aging Cell has revealed that a nematode species commonly used for aging research lives much longer on an alternate-day fasting regimen, but only when it is administered in middle age and only when the worms are consuming an animal-based protein source. Deciding what
Cellular Reprogramming Improves Cognition in Aged Rats
July 26, 2024
Scientists have shown that prolonged, continuous expression of reprogramming factors counters cognitive decline in old rats and probably decreases their epigenetic age [1]. Reprogramming and cognitive function Cellular reprogramming, the act of bringing differentiated cells back to a stem-like pluripotent state by expressing certain genes, has
Exploring Senescence in Tendon Function
July 25, 2024
In Aging Cell, researchers have published new data on the relationship between senescence and the extracellular matrix in the tendons of older people. Easy to injure, hard to heal The researchers begin this paper by pointing out that injuries to the musculoskeletal system are responsible for
A Switch to Whole Food Diets Benefits Elderly People
July 24, 2024
New research demonstrated how transitioning from a typical Western diet composed of processed foods to a whole-food diet improved cardiometabolic health and body composition and impacted gut microbiome metabolites in elderly people [1]. You are what you eat While this study was conducted in Australia, the
Antinuclear Antibody Shows Promise Against Cancer
July 23, 2024
Scientists have developed a conjugate of a drug and a nucleus-targeting antibody that can attack multiple types of cancer cells without targeting a particular antigen [1]. The anti-nuclear missile Antinuclear antibodies (ANA) are usually associated with autoimmune diseases, such as lupus, where those antibodies attack cellular
Exploring How Stiffness Promotes Osteoarthritis
July 22, 2024
In iScience, researchers have explained how physical mechanics can alter mitochondrial function in a way that leads to osteoarthritis. When simple physics affects biology Previous work has pinpointed abnormal mechanical loading, which occurs when joints are placed under excessive stresses in ways that they were not
Late-Life Treatment Increases Mouse Lifespan by 25%
July 19, 2024
A new mouse study has found that both germline knockout and late-life inhibition of the pro-inflammatory cytokine IL-11 lead to comparable and powerful healthspan and lifespan extension [1]. The inflammatory message As part of inflammaging, the pro-inflammatory cytokines that act as messengers, transferring and amplifying inflammatory
Discovering Why an Inflammatory Compound Inhibits Cancer
July 18, 2024
In Aging Cell, researchers have published their findings into why the inflammatory factor IL-6 inhibits cancerous tumors when generated inside the cell. IL-6 affects both senescence and cancer proliferation One of the core parts of the SASP is the inflammatory cytokine interleukin 6 (IL-6). While this
Probiotics Have Positive Cognitive Effects in Trial
July 17, 2024
A clinical trial has found that consuming a multi-species probiotic formulation positively impacts mental well-being and improves cognitive functions [1]. Gut-brain crosstalk The gut microbiome is a gathering of microorganisms in the human gut that plays multiple essential functions, from nutrient absorption to immune system modulation
Longevity Biotech Fellowship: Road To A Post-Aging Society
July 16, 2024
The Longevity Biotech Fellowship is one of the most interesting longevity-related initiatives in the last couple of years. Co-founded by Mark Hamalainen and Nathan Cheng, both well-known figures in the longevity field, LBF has been everywhere: presenting at conferences, participating in co-living projects such as Zuzalu
Mixed Results in Probiotic Trial Against Inflammaging
July 15, 2024
Researchers publishing in Probiotics and Antimicrobial Proteins have published the results of a clinical trial on the effects of a probiotic on inflammaging in older people. The gut and systemic inflammation The researchers begin this paper discussing their target of inflammaging, as this condition has been