Category: News
How Supplement Formulas, Including NOVOS, Affect Skin Aging
September 11, 2024
Researchers have tested several combinations of ingredients with anti-aging properties. Those combinations, including a 12-ingredient formulation created by NOVOS, helped to reduce DNA damage and oxidative stress in human skin
Medium LDL Levels Associated With Lowest Mortality
September 10, 2024
A new observational study suggests that lower LDL cholesterol levels are not necessarily better. Instead, the ratio of triglycerides to HDL may be more important [1]. Putting common wisdom to
Blocking a Dopamine Receptor May Improve Memory
September 9, 2024
Neurological researchers, in Aging Cell, have deepened our understanding of the brain, explaining how turning off a dopamine receptor may lead to better memory in older people. Sometimes it’s better
Associations Between Professional Sports and Longevity
September 9, 2024
A new study analyzed how being an elite athlete in various sports affects human lifespan. Some of the results were surprising [1]. Elite sports and aging Longevity enthusiasts have long
NILAR: A4LI’s Response to NIH Reform Proposal
September 6, 2024
The longevity advocacy and lobbying group has submitted detailed feedback to the congressional proposal to replace NIA with the National Institute on Dementia – and now you can sign the
Targeting Senescent Cells by Their Surface Markers
September 5, 2024
New research in Aging Cell has suggested that targeting senescent cells based on their surface proteins (surfaceome) may be effective in dealing with them. Focusing on what’s easiest to target
I Dined with Bryan Johnson and Didn’t Die
September 5, 2024
Anxious about being late and distrustful of LA’s afternoon traffic, I got to my destination quite a few minutes early and found myself in a quiet middle-class neighborhood. The house
Keto Diets May Help Cognitive Function in Alzheimer’s
September 4, 2024
The results of 10 independently conducted clinical trials suggest that ketogenic diets have a positive impact on the cognitive function of Alzheimer’s disease patients [1]. Keto instead of a pill?
Combination Therapy Works Against Pancreatic Cancer in Mice
September 3, 2024
In a new study, a multi-prong treatment combined with a clever delivery method has shown promise against one of the deadliest cancers [1]. Lethal and barely treatable Pancreatic ductal adenocarcinoma
Caffeic Acid Variant May Suppress Bone Deterioration
September 2, 2024
In Aging, researchers have described how a derivative of caffeic acid inhibits osteoclasts, the cells that break down bone. A modification of a tested compound We have recently published new
Rejuvenation Roundup August 2024
September 2, 2024
Summer’s at its end, but rejuvenation biotechnology is still heating up, with researchers discovering ways of vastly improving mouse lifespan and conducting a recruitment drive for young scientists. Here’s how
Some Cells Age Much Faster Than Others
August 30, 2024
In Stem Cell Reports, researchers have described how cell subpopulations and division affect the results of epigenetic clocks. Good, but never perfect As these researchers note, epigenetic clocks have had
Skin Aging and Cellular Mobility at the Protein Level
August 29, 2024
In Aging, researchers have described how the changing production of skin cells’ proteins is a core part of their age-related decline. Understanding why skin cells lose their function In healthy
NNMT Inhibitor Improves Muscle Function in Aged Mice
August 28, 2024
A recent paper has reported on improving muscle function in aged mice through combined treatment of exercise and the inhibition of NNMT, an enzyme involved in NAD+ metabolism [1]. Age-related
Weekend-Oriented Physical Activity Superior for Brain Health
August 27, 2024
According to a new study, “weekend warriors”, people who have most of their physical activity over one or two days a week, enjoy the most robust risk reduction for several
How Supplement Formulas, Including NOVOS, Affect Skin Aging
September 11, 2024
Researchers have tested several combinations of ingredients with anti-aging properties. Those combinations, including a 12-ingredient formulation created by NOVOS, helped to reduce DNA damage and oxidative stress in human skin cells in cultures [1]. Fighting multiple Hallmarks of Aging at once Aging impacts multiple cellular processes,
Medium LDL Levels Associated With Lowest Mortality
September 10, 2024
A new observational study suggests that lower LDL cholesterol levels are not necessarily better. Instead, the ratio of triglycerides to HDL may be more important [1]. Putting common wisdom to the test LDL cholesterol is largely considered harmful, but lower levels might not be beneficial according
Blocking a Dopamine Receptor May Improve Memory
September 9, 2024
Neurological researchers, in Aging Cell, have deepened our understanding of the brain, explaining how turning off a dopamine receptor may lead to better memory in older people. Sometimes it’s better for the dopamine not to hit With aging comes changes in how the brain processes dopamine
Associations Between Professional Sports and Longevity
September 9, 2024
A new study analyzed how being an elite athlete in various sports affects human lifespan. Some of the results were surprising [1]. Elite sports and aging Longevity enthusiasts have long wondered if professional athletes live longer than the general population and what sports show stronger associations
NILAR: A4LI’s Response to NIH Reform Proposal
September 6, 2024
The longevity advocacy and lobbying group has submitted detailed feedback to the congressional proposal to replace NIA with the National Institute on Dementia – and now you can sign the petition. No, dementia doesn’t equal aging Back in June, the longevity community was rattled by the
Targeting Senescent Cells by Their Surface Markers
September 5, 2024
New research in Aging Cell has suggested that targeting senescent cells based on their surface proteins (surfaceome) may be effective in dealing with them. Focusing on what’s easiest to target Senescence and the SASP have well-known markers, such as p16, p21, and the well-known SA-β-gal [1].
I Dined with Bryan Johnson and Didn’t Die
September 5, 2024
Anxious about being late and distrustful of LA’s afternoon traffic, I got to my destination quite a few minutes early and found myself in a quiet middle-class neighborhood. The house I was looking for did stand out from the rest but rather modestly so. A week
Keto Diets May Help Cognitive Function in Alzheimer’s
September 4, 2024
The results of 10 independently conducted clinical trials suggest that ketogenic diets have a positive impact on the cognitive function of Alzheimer’s disease patients [1]. Keto instead of a pill? Despite extensive research, there is stilll no effective treatment for Alzheimer’s disease. Therefore, approaches that aim
Combination Therapy Works Against Pancreatic Cancer in Mice
September 3, 2024
In a new study, a multi-prong treatment combined with a clever delivery method has shown promise against one of the deadliest cancers [1]. Lethal and barely treatable Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest types of cancer. It is rarely diagnosed early and very
Caffeic Acid Variant May Suppress Bone Deterioration
September 2, 2024
In Aging, researchers have described how a derivative of caffeic acid inhibits osteoclasts, the cells that break down bone. A modification of a tested compound We have recently published new information on what triggers the imbalance between bone-destroying osteoclasts and bone-building osteoblasts. This is a well-known
Rejuvenation Roundup August 2024
September 2, 2024
Summer’s at its end, but rejuvenation biotechnology is still heating up, with researchers discovering ways of vastly improving mouse lifespan and conducting a recruitment drive for young scientists. Here’s how the field was advanced in August. Interviews Michael Antonov: from Oculus to Longevity Biotech: After Oculus
Some Cells Age Much Faster Than Others
August 30, 2024
In Stem Cell Reports, researchers have described how cell subpopulations and division affect the results of epigenetic clocks. Good, but never perfect As these researchers note, epigenetic clocks have had successes in analyzing the impact of things that impact biological age, such as the effects of
Skin Aging and Cellular Mobility at the Protein Level
August 29, 2024
In Aging, researchers have described how the changing production of skin cells’ proteins is a core part of their age-related decline. Understanding why skin cells lose their function In healthy skin, dermal fibroblasts produce the proteins needed to maintain the extracellular matrix (ECM), the network of
NNMT Inhibitor Improves Muscle Function in Aged Mice
August 28, 2024
A recent paper has reported on improving muscle function in aged mice through combined treatment of exercise and the inhibition of NNMT, an enzyme involved in NAD+ metabolism [1]. Age-related muscle loss Muscle loss is a common problem in the aging population. Studies estimate that “after
Weekend-Oriented Physical Activity Superior for Brain Health
August 27, 2024
According to a new study, “weekend warriors”, people who have most of their physical activity over one or two days a week, enjoy the most robust risk reduction for several brain health-related conditions [1]. Couch potato, except on weekends Exercise is universally necessary to stay healthy