Lifespan Research Institute

Category: News

Mouse on wheel

A Molecular Reason Why Exercise Fights Senescence

Researchers publishing in Aging have found a molecule linking exercise to the inhibition of cellular senescence, one of the hallmarks of aging. Exercise against senescence We recently reported on a

Dying cancer

Novel Drug Suppresses Metastatic Cancer in Mice

Scientists have found a small molecule that turns an anti-apoptotic protein into a pro-apoptotic one, protecting against deadly metastases in a mouse model of human triple-negative breast cancer and, potentially,

Lungs

A New Target for Chronic Lung Diseases

Revealing their findings in Aging Cell, researchers have found a new biochemical target for chronic obstructive pulmonary disease (COPD). Smoking is only one cause COPD, which is characterized by bouts

Longevity Desci Recap June 2024

Longevity and DeSci Recap – June 2024

This summer season is red hot in the world of longevity. Packed with interesting events, investments and new research proposals, the future of longevity is becoming today’s reality. Join us

Rejuvenation Roundup June 2024

Rejuvenation Roundup June 2024

Puzzle pieces are being fit together and connections are being made in understanding the massive number of biological changes that make up aging. Here’s how the science has progressed in

Hitting the brakes

70 Is Indeed the New 60, Study Suggests

Scientists have found that older people currently retain more youthful abilities than people who were the same age did in previous decades [1]. How miserable are we? Recent decades have

White blood cells

Modified Natural Killer Cells Effective Against Liver Cancer

By making NK cells insensitive to tumor-secreted TGF-β, scientists have improved their efficacy against this deadly hepatocellular carcinoma (HCC) [1]. Liver cancer and TGF-β Cancer cells, which are supposed to be vulnerable to the immune system, develop various defensive mechanisms to avoid detection and decrease immune

Older people with cognitive decline

Sex Differences in the Blood-Brain Barrier and Alzheimer’s

Researchers have found that men and women have significant differences in how their brains’ blood vessels change in Alzheimer’s disease. The collapse of the blood-brain barrier This research begins with a discussion of Alzheimer’s and its two principal symptoms: the well-known plaques that coat the brain,

Older person eating vegetables

Precision Nutrition Improves Life Quality for Older People

Researchers compared general nutritional advice to individualized nutritional advice in addition to an app that encourages its users to follow a diet. Elderly overweight and obese people benefited more from the individualized approach [1]. One size doesn’t fit all Proper diets can help people stay healthy

Exploding cell

Scientists Eliminate Cancer Using Evolutionary Principles

A new study describes a method of genetically modifying a fraction of tumor cells, programming them to self-destruct and take therapy-resistant cells with them [1]. Resisting the resistance Advanced solid tumors remain the main challenge for modern oncology. It’s hard to deliver a therapy to all

Mouse on wheel

A Molecular Reason Why Exercise Fights Senescence

Researchers publishing in Aging have found a molecule linking exercise to the inhibition of cellular senescence, one of the hallmarks of aging. Exercise against senescence We recently reported on a team of researchers looking to protect against chronic obstructive pulmonary disease (COPD) by focusing on possible

Dying cancer

Novel Drug Suppresses Metastatic Cancer in Mice

Scientists have found a small molecule that turns an anti-apoptotic protein into a pro-apoptotic one, protecting against deadly metastases in a mouse model of human triple-negative breast cancer and, potentially, in other cancers [1]. Small but mighty With cutting-edge cancer treatments now including things like antibodies

Lungs

A New Target for Chronic Lung Diseases

Revealing their findings in Aging Cell, researchers have found a new biochemical target for chronic obstructive pulmonary disease (COPD). Smoking is only one cause COPD, which is characterized by bouts of lung problems, has only limited treatments, is progressive and currently incurable, and often occurs in

Elderly woman with dementia

Recurrent Pregnancy Loss Associated with Increased Dementia

A recent paper in the European Journal of Epidemiology reported that recurrent miscarriage and stillbirths are associated with the occurrence of dementia, but there was insufficient evidence to establish such a connection between infertility and dementia [1]. Sex-specific differences in dementia risk Dementia affects women more

Longevity Desci Recap June 2024

Longevity and DeSci Recap – June 2024

This summer season is red hot in the world of longevity. Packed with interesting events, investments and new research proposals, the future of longevity is becoming today’s reality. Join us as we run through the happenings of June 2024 and what’s been going on in the

Longevity Summit Dublin

Four Days of Longevity in Dublin: Conference Highlights

The annual Longevity Summit Dublin happened this June, and we are bringing you the highlights. Initiated by Aubrey de Grey and Martin O’Dea in 2022, this conference has earned a reputation for combining scientific depth with just the right amount of quirkiness over full four days

Peripheral artery disease

Nicotinamide Riboside Improves Walking in Clinical Trial

Researchers publishing in Nature Communications have found that nicotinamide riboside (NR) improves walking distance for people who have peripheral artery disease (PAD) in the legs. When the arms and legs don’t get enough blood Ischemia, the failure of blood vessels to deliver sufficient oxygen and nutrients,

Rejuvenation Roundup June 2024

Rejuvenation Roundup June 2024

Puzzle pieces are being fit together and connections are being made in understanding the massive number of biological changes that make up aging. Here’s how the science has progressed in June. LEAF News Team and activities Summer Could Be Big for Longevity Tech Investment: The weather

Choosing a clock

Developing a New Aging Clock for Medical Professionals

In Nature Aging, researchers have published the creation of a new clock that uses multiple metrics to evaluate biological aging. What’s worth measuring? Multiple metrics have been used to measure aging. The most commonly known in the literature are the epigenetic clocks, such as GrimAge and

Hitting the brakes

70 Is Indeed the New 60, Study Suggests

Scientists have found that older people currently retain more youthful abilities than people who were the same age did in previous decades [1]. How miserable are we? Recent decades have seen leaps in average life expectancy. However, those mostly stem from successes in curbing childhood mortality

Mitochondria

Encouraging Mitochondrial Maintenance to Fight Senescence

Researchers have published a method of rescuing cells from damaged mitochondria and cellular senescence, potentially alleviating major aspects of aging. Bad mitochondria must be consumed A core part of autophagy involves selective autophagy receptors (SARs), which build the autophagosomes in which the organelles are consumed [1].