Category: News
New Epigenetic Clock Built on Lurking DNA Fragments
August 5, 2024
In Aging Cell, a team of researchers has announced Retroelement-Age, a novel clock that focuses on the expression of buried pieces of DNA that are normally suppressed. Corrupted but unexpressed
Longevity and DeSci Recap – July 2024
August 5, 2024
The Longevity and DeSci Recap is back, and our latest edition covers high-profile events including the Longevity Investors Conference in Gstaad, new innovations in AFib monitoring, and even some celebrity-related
Vegan Diet Lowers Biological Age in a New Study
August 2, 2024
In a study that involved pairs of identical twins, Stanford scientists have shown that a healthy vegan diet leads to a decrease in biological age and possibly to other health
Rapamycin + Trametinib Increase Mouse Lifespan by up to 35%
August 1, 2024
Combining rapamycin and trametinib seemed to have a cumulative effect in both sexes but mostly in females [1]. These results are probably due to a reduction in both cancer and
Rejuvenation Roundup July 2024
August 1, 2024
Entirely new approaches with surprisingly good results have been recently discovered and published in July’s papers. Here’s what the research world has revealed this month. LEAF News Interviews Longevity Biotech
Very Old People Have Healthy Gut Bacteria
July 31, 2024
The authors of a recent review investigated what is known about gut microbiota in centenarians and how gut microbes can help people achieve extreme longevity [1]. What makes centenarians special?
A Key Pathway for Sarcopenia Reversal
July 30, 2024
In Aging Cell, researchers have published a paper on a cellular energy source that appears to be a key signaling molecule in sarcopenia. A little-explored molecule Sarcopenia, a condition that
Senescence May Play a Significant Role in Parkinson’s
July 29, 2024
In Aging, a pair of researchers has published a perspective connecting fat (lipid) accumulation and cellular senescence in neurons to Parkinson’s disease. α-syn, but not just α-syn Parkinson’s disease is
Surprising Effects of Regular Fasting in Model Organisms
July 28, 2024
Research published in Aging Cell has revealed that a nematode species commonly used for aging research lives much longer on an alternate-day fasting regimen, but only when it is administered
Cellular Reprogramming Improves Cognition in Aged Rats
July 26, 2024
Scientists have shown that prolonged, continuous expression of reprogramming factors counters cognitive decline in old rats and probably decreases their epigenetic age [1]. Reprogramming and cognitive function Cellular reprogramming, the
Exploring Senescence in Tendon Function
July 25, 2024
In Aging Cell, researchers have published new data on the relationship between senescence and the extracellular matrix in the tendons of older people. Easy to injure, hard to heal The
A Switch to Whole Food Diets Benefits Elderly People
July 24, 2024
New research demonstrated how transitioning from a typical Western diet composed of processed foods to a whole-food diet improved cardiometabolic health and body composition and impacted gut microbiome metabolites in
Antinuclear Antibody Shows Promise Against Cancer
July 23, 2024
Scientists have developed a conjugate of a drug and a nucleus-targeting antibody that can attack multiple types of cancer cells without targeting a particular antigen [1]. The anti-nuclear missile Antinuclear
Exploring How Stiffness Promotes Osteoarthritis
July 22, 2024
In iScience, researchers have explained how physical mechanics can alter mitochondrial function in a way that leads to osteoarthritis. When simple physics affects biology Previous work has pinpointed abnormal mechanical
Late-Life Treatment Increases Mouse Lifespan by 25%
July 19, 2024
A new mouse study has found that both germline knockout and late-life inhibition of the pro-inflammatory cytokine IL-11 lead to comparable and powerful healthspan and lifespan extension [1]. The inflammatory
New Epigenetic Clock Built on Lurking DNA Fragments
August 5, 2024
In Aging Cell, a team of researchers has announced Retroelement-Age, a novel clock that focuses on the expression of buried pieces of DNA that are normally suppressed. Corrupted but unexpressed The natural human genome has a large number of artifacts left over from ancient viral infections
Longevity and DeSci Recap – July 2024
August 5, 2024
The Longevity and DeSci Recap is back, and our latest edition covers high-profile events including the Longevity Investors Conference in Gstaad, new innovations in AFib monitoring, and even some celebrity-related news. This month, we’ll continue to explore the latest events, current research, and investment news to
Vegan Diet Lowers Biological Age in a New Study
August 2, 2024
In a study that involved pairs of identical twins, Stanford scientists have shown that a healthy vegan diet leads to a decrease in biological age and possibly to other health benefits [1]. Do you really live longer if you eat well? A good diet can do
Rapamycin + Trametinib Increase Mouse Lifespan by up to 35%
August 1, 2024
Combining rapamycin and trametinib seemed to have a cumulative effect in both sexes but mostly in females [1]. These results are probably due to a reduction in both cancer and inflammation. A winning combo The idea that combination treatments are the future of life extension is
Rejuvenation Roundup July 2024
August 1, 2024
Entirely new approaches with surprisingly good results have been recently discovered and published in July’s papers. Here’s what the research world has revealed this month. LEAF News Interviews Longevity Biotech Fellowship: Road To A Post-Aging Society: The Longevity Biotech Fellowship is one of the most interesting
Very Old People Have Healthy Gut Bacteria
July 31, 2024
The authors of a recent review investigated what is known about gut microbiota in centenarians and how gut microbes can help people achieve extreme longevity [1]. What makes centenarians special? One way of investigating what gives people longevity and health in older ages is to study
A Key Pathway for Sarcopenia Reversal
July 30, 2024
In Aging Cell, researchers have published a paper on a cellular energy source that appears to be a key signaling molecule in sarcopenia. A little-explored molecule Sarcopenia, a condition that increases with aging, reduces muscle mass in older people, and leads to a decreased quality of
Senescence May Play a Significant Role in Parkinson’s
July 29, 2024
In Aging, a pair of researchers has published a perspective connecting fat (lipid) accumulation and cellular senescence in neurons to Parkinson’s disease. α-syn, but not just α-syn Parkinson’s disease is characterized by the loss of a specific population of neurons: the dopaminergic neurons in the substantia
Surprising Effects of Regular Fasting in Model Organisms
July 28, 2024
Research published in Aging Cell has revealed that a nematode species commonly used for aging research lives much longer on an alternate-day fasting regimen, but only when it is administered in middle age and only when the worms are consuming an animal-based protein source. Deciding what
Cellular Reprogramming Improves Cognition in Aged Rats
July 26, 2024
Scientists have shown that prolonged, continuous expression of reprogramming factors counters cognitive decline in old rats and probably decreases their epigenetic age [1]. Reprogramming and cognitive function Cellular reprogramming, the act of bringing differentiated cells back to a stem-like pluripotent state by expressing certain genes, has
Exploring Senescence in Tendon Function
July 25, 2024
In Aging Cell, researchers have published new data on the relationship between senescence and the extracellular matrix in the tendons of older people. Easy to injure, hard to heal The researchers begin this paper by pointing out that injuries to the musculoskeletal system are responsible for
A Switch to Whole Food Diets Benefits Elderly People
July 24, 2024
New research demonstrated how transitioning from a typical Western diet composed of processed foods to a whole-food diet improved cardiometabolic health and body composition and impacted gut microbiome metabolites in elderly people [1]. You are what you eat While this study was conducted in Australia, the
Antinuclear Antibody Shows Promise Against Cancer
July 23, 2024
Scientists have developed a conjugate of a drug and a nucleus-targeting antibody that can attack multiple types of cancer cells without targeting a particular antigen [1]. The anti-nuclear missile Antinuclear antibodies (ANA) are usually associated with autoimmune diseases, such as lupus, where those antibodies attack cellular
Exploring How Stiffness Promotes Osteoarthritis
July 22, 2024
In iScience, researchers have explained how physical mechanics can alter mitochondrial function in a way that leads to osteoarthritis. When simple physics affects biology Previous work has pinpointed abnormal mechanical loading, which occurs when joints are placed under excessive stresses in ways that they were not
Late-Life Treatment Increases Mouse Lifespan by 25%
July 19, 2024
A new mouse study has found that both germline knockout and late-life inhibition of the pro-inflammatory cytokine IL-11 lead to comparable and powerful healthspan and lifespan extension [1]. The inflammatory message As part of inflammaging, the pro-inflammatory cytokines that act as messengers, transferring and amplifying inflammatory