Lifespan Research Institute

Category: News

Rejuvenation Roundup April 2024

Rejuvenation Roundup April 2024

Last month has brought forward a lot of exciting news in the longevity industry, including our own upcoming merger with SENS. Here’s what’s happened in April. LEAF News SENS Research

Lung cancer

A Protein Potently Suppresses Lung Cancer in Mice

Scientists have identified the proteins FOXF1 and its downstream target FZD4 as potential targets for treating lung cancer. Upregulating them helps to normalize vasculature in the tumor area and suppresses

Cells with shrunken mitochondria

Older and Younger Cells Handle Genes Differently

In Aging Cell, researchers have published evidence that downregulating a key aspect of lipid metabolism harms mitochondrial function, but only in cells taken from younger people. Fat regulation at the

Diabetes in aging

Looking for Causality in Diabetes and Aging

Researchers have published the results of a study in Aging Cell, finding some evidence that type 2 diabetes causes accelerated aging. Later-generation clocks only This paper begins with explanations of

Data analysis

A Re-Analysis Finds Potential Life-Prolonging Compounds

The authors of a recent paper published in GeroScience used an alternative statistical test to reanalyze data from the Interventions Testing Program and identified additional life‑extending compounds [1]. The crucial

Vitalia

Vitalia: Living the Longevity Dream

On the tropical island of Roatán, a bunch of people gathered in an unprecedented, longevity-themed pop-up city – and then some of them stayed, making the venture permanent. “You’re going

Anti-drug

Cannabis Use Linked to Cardiovascular Problems

According to a new study, cannabis consumption is associated with increased risks of coronary heart disease, stroke, and heart attack [1]. It’s growing popular, but is it good for you?

Muscle fibers

Taking a Look at Proteins in Exercise and Aging

With an in-depth examination tool in hand, researchers publishing in Aging have done a preliminary examination of the muscle protein differences between younger and older people and how older people’s

Day Night Cycle

Aging Measurements Can Vary by Time of Day

Epigenetic aging measurements can vary by the time of day at which they are taken, according to a study published in Aging Cell. The circadian rhythm Living on Earth, organisms

Buff old man

Autophagy Is Essential for Healthy Muscles

A study published in Aging Cell has reported that older people with better regulated autophagy in their skeletal muscles have less age-related frailty. Taking out the trash The researchers begin

Ovary diagnostics

Quercetin Delays Ovarian Aging in Middle-Aged Mice

A recent paper published in Nature Aging dives into the gene expression differences between young, middle-aged, and older human ovaries and tests possible interventions to slow down their aging processes

Ramadan meal

Intermittent Fasting Induces Changes in Multiple Biomarkers

A study published in Human Nutrition & Metabolism found that prolonged intermittent fasting causes the expression of genes involved in autophagy, the inflammasome, and senescence to change [1]. Fasting your way to better health and longevity? Previous research has linked fasting to delaying the onset of

Rejuvenation Roundup April 2024

Rejuvenation Roundup April 2024

Last month has brought forward a lot of exciting news in the longevity industry, including our own upcoming merger with SENS. Here’s what’s happened in April. LEAF News SENS Research Foundation and Lifespan.io Announce Intent to Merge, Forming a Novel Longevity Entity: SENS Research Foundation and

Lung cancer

A Protein Potently Suppresses Lung Cancer in Mice

Scientists have identified the proteins FOXF1 and its downstream target FZD4 as potential targets for treating lung cancer. Upregulating them helps to normalize vasculature in the tumor area and suppresses this lethal type of cancer [1]. Lung cancer and vasculature Lung cancer remains one of the

Cells with shrunken mitochondria

Older and Younger Cells Handle Genes Differently

In Aging Cell, researchers have published evidence that downregulating a key aspect of lipid metabolism harms mitochondrial function, but only in cells taken from younger people. Fat regulation at the cellular level Perilipins (PLINs) are proteins that regulate the use of fats (lipids) within cells. This

Empty chair

Interrupting Sitting with Activity Lowers Glucose Levels

Scientists have discovered that frequently interrupting prolonged sitting with physical activity, such as short walks or squats, can help control glucose levels in overweight and obese males [1]. Don’t just sit there! Prolonged sitting is the curse of modern times. It has been associated with various

Diabetes in aging

Looking for Causality in Diabetes and Aging

Researchers have published the results of a study in Aging Cell, finding some evidence that type 2 diabetes causes accelerated aging. Later-generation clocks only This paper begins with explanations of Type 2 diabetes and epigenetic clocks, noting that principal component (PC) versions of clocks may give

Data analysis

A Re-Analysis Finds Potential Life-Prolonging Compounds

The authors of a recent paper published in GeroScience used an alternative statistical test to reanalyze data from the Interventions Testing Program and identified additional life‑extending compounds [1]. The crucial step of data analysis A typical biological experiment can be divided into three stages: planning, executing,

Vitalia

Vitalia: Living the Longevity Dream

On the tropical island of Roatán, a bunch of people gathered in an unprecedented, longevity-themed pop-up city – and then some of them stayed, making the venture permanent. “You’re going where?” A friend invited me over, but I declined, telling him I had to travel for

Anti-drug

Cannabis Use Linked to Cardiovascular Problems

According to a new study, cannabis consumption is associated with increased risks of coronary heart disease, stroke, and heart attack [1]. It’s growing popular, but is it good for you? After decades of being banned and demonized, marijuana is making a huge comeback, thanks to a

Muscle fibers

Taking a Look at Proteins in Exercise and Aging

With an in-depth examination tool in hand, researchers publishing in Aging have done a preliminary examination of the muscle protein differences between younger and older people and how older people’s proteins change with exercise. The power to take a close look This paper begins with a

Day Night Cycle

Aging Measurements Can Vary by Time of Day

Epigenetic aging measurements can vary by the time of day at which they are taken, according to a study published in Aging Cell. The circadian rhythm Living on Earth, organisms have evolved to adapt to our planet’s day/night cycle. This adaptation is known as the circadian

Young mouse and old mouse

Young Extracellular Vesicles Extend Life in Old Mice

Tiny bubbles that cells use to communicate with each other prolonged lifespan and reversed numerous aging phenotypes when taken from young mice and injected into old ones, even though the treatment started late in life [1]. The tiny messengers For millennia, humans credited young blood with

Buff old man

Autophagy Is Essential for Healthy Muscles

A study published in Aging Cell has reported that older people with better regulated autophagy in their skeletal muscles have less age-related frailty. Taking out the trash The researchers begin this paper by discussing the various activities and effects of autophagy. Obviously, too much autophagy is

Ovary diagnostics

Quercetin Delays Ovarian Aging in Middle-Aged Mice

A recent paper published in Nature Aging dives into the gene expression differences between young, middle-aged, and older human ovaries and tests possible interventions to slow down their aging processes [1]. An underexplored area of human aging Female reproductive aging remains a relatively unexplored area of

Gerosense logo

Gero Announces Activity-Based Longevity Studies Initiative

The longevity company Gero has presented its new nonprofit initiative: a series of studies using the company’s aging clock, which is based on stepping patterns obtained from phones and wearables. One small step for man, one giant leap for aging research? Gero, an AI longevity company,