Category: News
Autophagy Is Essential for Healthy Muscles
April 18, 2024
A study published in Aging Cell has reported that older people with better regulated autophagy in their skeletal muscles have less age-related frailty. Taking out the trash The researchers begin
Quercetin Delays Ovarian Aging in Middle-Aged Mice
April 17, 2024
A recent paper published in Nature Aging dives into the gene expression differences between young, middle-aged, and older human ovaries and tests possible interventions to slow down their aging processes
Gero Announces Activity-Based Longevity Studies Initiative
April 16, 2024
The longevity company Gero has presented its new nonprofit initiative: a series of studies using the company’s aging clock, which is based on stepping patterns obtained from phones and wearables.
An Inflammatory Molecule May Also Encourage Obesity
April 15, 2024
A team of researchers has waded into a controversial and contradictory area of study, publishing information on the link between obesity and an inflammatory molecule that increases with aging. A
Mitochondria Injection Alleviates Parkinson’s in Mice
April 12, 2024
Scientists have tested a novel method of providing cells with healthy mitochondria to fight Parkinson’s disease [1]. Replacing damaged mitochondria Parkinson’s disease is the second-most prevalent neurodegenerative disorder, and it
Very Long-Lived People Have Protected Epigenetics
April 11, 2024
A team of researchers has reported in Aging Cell that longer-lived Chinese women have less epigenetic noise in crucial areas of the genome. Order and disorder We have previously reported
New Gene Therapy Reverses Atherosclerosis In Mice
April 10, 2024
Repair Biotechnologies, a company based in Syracuse, New York, has announced findings from early research suggesting that its technology can quickly stop the advancement of atherosclerosis. While these preclinical results
Some Medications Associated with Improved Aging Biomarkers
April 10, 2024
The authors of a recent study published in Aging Cell tested 21 groups of medication used by the elderly and reported that some of them impact aging biomarkers [1]. Repurposing
Reprogramming Helps Old Mice Produce More Neurons
April 9, 2024
Scientists have found that partial cellular reprogramming, both full-body and restricted to specific brain regions, rescues neurogenesis in the brains of old mice [1]. Cells going back in time Partial
Finding Senolytics to Stop Lung Disease
April 8, 2024
Researchers publishing in the Journal of Clinical Investigation have developed a new method of screening for compounds, and they found one that appears to directly attack senescent cells involved in
Scientists Discover a New Mechanism of Age-Related Obesity
April 5, 2024
A new study suggests that the reason why aging is associated with obesity lies in specific neurons found in the brain [1]. Tell that to the brain It is often hard
Small Molecules Reverse Many Age-Related Changes in Cells
April 4, 2024
A team of Harvard researchers has published a paper in eLife detailing the downstream effects of small molecule partial cellular reprogramming. Rejuvenating cells from the ground up We have recently
SENS Research Foundation and Lifespan.io Announce Merge
April 3, 2024
NEW YORK, April 3, 2024 – In a groundbreaking announcement set to impact the future of longevity research and outreach, two historic longevity nonprofits – SENS Research Foundation and Lifespan.io
Senolytic CAR T Cells Rescue Intestinal Aging in Mice
April 3, 2024
Scientists have demonstrated that CAR T cells can be employed against senescent intestinal stem cells, improving regeneration and ameliorating age-related symptoms such as “leaky gut” [1]. Cell-on-cell warfare Cellular senescence
More Social Connections Associated with Slower Aging
April 3, 2024
Recent research has contributed to the growing body of evidence regarding social isolation, loneliness, and biological aging [1]. Social isolation is not generally screened for During doctor visits, patients are
Autophagy Is Essential for Healthy Muscles
April 18, 2024
A study published in Aging Cell has reported that older people with better regulated autophagy in their skeletal muscles have less age-related frailty. Taking out the trash The researchers begin this paper by discussing the various activities and effects of autophagy. Obviously, too much autophagy is
Quercetin Delays Ovarian Aging in Middle-Aged Mice
April 17, 2024
A recent paper published in Nature Aging dives into the gene expression differences between young, middle-aged, and older human ovaries and tests possible interventions to slow down their aging processes [1]. An underexplored area of human aging Female reproductive aging remains a relatively unexplored area of
Gero Announces Activity-Based Longevity Studies Initiative
April 16, 2024
The longevity company Gero has presented its new nonprofit initiative: a series of studies using the company’s aging clock, which is based on stepping patterns obtained from phones and wearables. One small step for man, one giant leap for aging research? Gero, an AI longevity company,
An Inflammatory Molecule May Also Encourage Obesity
April 15, 2024
A team of researchers has waded into a controversial and contradictory area of study, publishing information on the link between obesity and an inflammatory molecule that increases with aging. A context-dependent molecule The authors point out previous research that singled out the interleukin IL-6, a key
Mitochondria Injection Alleviates Parkinson’s in Mice
April 12, 2024
Scientists have tested a novel method of providing cells with healthy mitochondria to fight Parkinson’s disease [1]. Replacing damaged mitochondria Parkinson’s disease is the second-most prevalent neurodegenerative disorder, and it affects 10 million people worldwide. The disease is age-related, as its prevalence rises rapidly in people
Very Long-Lived People Have Protected Epigenetics
April 11, 2024
A team of researchers has reported in Aging Cell that longer-lived Chinese women have less epigenetic noise in crucial areas of the genome. Order and disorder We have previously reported that the accumulation of epigenetic noise appears to be the main cause of epigenetic alterations. Multiple
New Gene Therapy Reverses Atherosclerosis In Mice
April 10, 2024
Repair Biotechnologies, a company based in Syracuse, New York, has announced findings from early research suggesting that its technology can quickly stop the advancement of atherosclerosis. While these preclinical results are in mice, this approach has the potential for treating atherosclerosis in humans. In March, the
Some Medications Associated with Improved Aging Biomarkers
April 10, 2024
The authors of a recent study published in Aging Cell tested 21 groups of medication used by the elderly and reported that some of them impact aging biomarkers [1]. Repurposing existing drugs to fight aging The search for drugs that slow aging includes finding new compounds
Reprogramming Helps Old Mice Produce More Neurons
April 9, 2024
Scientists have found that partial cellular reprogramming, both full-body and restricted to specific brain regions, rescues neurogenesis in the brains of old mice [1]. Cells going back in time Partial reprogramming improves various health metrics and increases lifespan in animal models [2]. For instance, Dr. David
Finding Senolytics to Stop Lung Disease
April 8, 2024
Researchers publishing in the Journal of Clinical Investigation have developed a new method of screening for compounds, and they found one that appears to directly attack senescent cells involved in lung fibrosis. A disease of senescence Senescent cells are a major part of an age-related lung
Scientists Discover a New Mechanism of Age-Related Obesity
April 5, 2024
A new study suggests that the reason why aging is associated with obesity lies in specific neurons found in the brain [1]. Tell that to the brain It is often hard to lose weight, and it becomes harder with age. While it seems simple enough to eat
Small Molecules Reverse Many Age-Related Changes in Cells
April 4, 2024
A team of Harvard researchers has published a paper in eLife detailing the downstream effects of small molecule partial cellular reprogramming. Rejuvenating cells from the ground up We have recently reported on a review of partial cellular reprogramming that used a cocktail of small molecules named
SENS Research Foundation and Lifespan.io Announce Merge
April 3, 2024
NEW YORK, April 3, 2024 – In a groundbreaking announcement set to impact the future of longevity research and outreach, two historic longevity nonprofits – SENS Research Foundation and Lifespan.io (Lifespan Extension Advocacy Foundation) – have unveiled plans to merge, upon completion of regulatory approvals. Lifespan.io,
Senolytic CAR T Cells Rescue Intestinal Aging in Mice
April 3, 2024
Scientists have demonstrated that CAR T cells can be employed against senescent intestinal stem cells, improving regeneration and ameliorating age-related symptoms such as “leaky gut” [1]. Cell-on-cell warfare Cellular senescence is a heterogeneous phenomenon in which cells stop dividing and malfunction, driving up inflammation. While senescent
More Social Connections Associated with Slower Aging
April 3, 2024
Recent research has contributed to the growing body of evidence regarding social isolation, loneliness, and biological aging [1]. Social isolation is not generally screened for During doctor visits, patients are often screened for many physical conditions. However, screening for social isolation in the clinic is not