Category: News
Niacin (Vitamin B3) Linked to Cardiovascular Risk
February 29, 2024
A new study shows that niacin, a popular food fortifier, supplement, and NAD precursor, might increase the risk of major adverse cardiovascular events by as much as twofold [1]. The
Higher Abdominal Fat Associated with Cognitive Decline
February 28, 2024
A group of Japanese researchers has published a paper reporting an association between higher abdominal fat levels and cognitive decline [1]. Abdominal fat and brain connection Aging is often linked
Physically Fit Older People Have Better Visual Processing
February 27, 2024
Publishing a study in GeroScience featuring people over 80 years old, researchers have described a link between physical fitness and maintenance of specific brain functions. Executive functions This paper begins
Epigenetic Clocks Help Predict Health Outcomes
February 26, 2024
Researchers publishing in PNAS have found that well-known epigenetic clocks are valuable in predicting health outcomes, including mortality, in human beings. The usefulness of clocks This paper begins with a
Fasting-Mimicking Diet Might Extend Lifespan in Humans
February 23, 2024
A new study into Valter Longo’s fasting-mimicking diet shows metabolic and immune benefits that, according to a simulation, might translate into years of additional lifespan [1]. Fasting in disguise Caloric
Meaningful Improvements in Human Trial For Sarcopenia
February 22, 2024
Rejuvenate Biomed has recently concluded a clinical trial for sarcopenia. The results have shown “meaningful improvements in muscle strength, function and fatigue resistance”. What is sarcopenia? Sarcopenia is an age-related
A Nanoparticle Reduces Brain Inflammation in Mice
February 22, 2024
A recent preprint paper from researchers at Sachi Bio has described how this company’s technology can be used to alleviate brain inflammation in a mouse model. The problem of tau
Educational Attainment Linked to Lower Mortality Risk
February 21, 2024
A systematic review and meta-analysis published in the Lancet suggests that more years of education is linked to reduced all-cause mortality in adults [1]. Benefits of education Educational attainment is
Rejuvenate Bio Develops Gene Therapy for Dog Arthritis
February 20, 2024
Rejuvenate Bio has announced a partnership with a leading animal health company to develop a gene therapy for canine osteoarthritis. The identity of the partnering global company is as yet
How Individual Lifestyle Factors Affect Lifespan
February 20, 2024
A new study has reported that adopting more healthy lifestyle habits continuously lowers mortality risk, resulting in many years of added life expectancy [1]. The magnificent eight Lead a healthy
Connecting Gut Metabolism to Grip Strength
February 19, 2024
In Aging, a team of researchers has outlined a possible relationship between low grip strength and compounds in the gut microbiome. The gut-muscle axis As these researchers note, previous work
Solving Atherosclerosis: The Small but Mighty Molecule
February 19, 2024
Cyclarity Therapeutics is developing an affordable, plaque-busting small molecule that may be the cure for the world’s number one killer: cardiovascular disease. With human trials planned for this year, we
The Latest in Rapamycin Research on Humans
February 18, 2024
Reviewers have gone through the latest updates on studies featuring rapamycin and its derivatives in The Lancet Healthy Longevity. Testing a well-known longevity promoter Not many compounds actually extend life
New Drug Shows Promise Against Glioblastoma
February 16, 2024
Scientists have discovered a small molecule that effectively kills glioblastoma, a highly aggressive and untreatable brain cancer, in cellular cultures [1]. When acidic means deadly Despite scientists’ best efforts, some
How Aging Leads to a Gene Transcription Problem
February 15, 2024
In Nature Genetics, researchers have described how a defect in RNA transcription constitutes a previously undiscovered mechanism of aging. When the blueprint becomes harder to read Gene expression begins when
Niacin (Vitamin B3) Linked to Cardiovascular Risk
February 29, 2024
A new study shows that niacin, a popular food fortifier, supplement, and NAD precursor, might increase the risk of major adverse cardiovascular events by as much as twofold [1]. The dark side of niacin? Vitamins are good for you, but caveats apply. Too much of some
Higher Abdominal Fat Associated with Cognitive Decline
February 28, 2024
A group of Japanese researchers has published a paper reporting an association between higher abdominal fat levels and cognitive decline [1]. Abdominal fat and brain connection Aging is often linked to many comorbidities, one of which is dementia, and developing drugs to treat this condition is
Physically Fit Older People Have Better Visual Processing
February 27, 2024
Publishing a study in GeroScience featuring people over 80 years old, researchers have described a link between physical fitness and maintenance of specific brain functions. Executive functions This paper begins with a description of executive functions, the basic abilities involved in performing the fundamental goal-oriented behaviors
Epigenetic Clocks Help Predict Health Outcomes
February 26, 2024
Researchers publishing in PNAS have found that well-known epigenetic clocks are valuable in predicting health outcomes, including mortality, in human beings. The usefulness of clocks This paper begins with a discussion of epigenetic clocks, most notably the later-generation clocks, such as PhenoAge, DunedinPACE, and the strong
Fasting-Mimicking Diet Might Extend Lifespan in Humans
February 23, 2024
A new study into Valter Longo’s fasting-mimicking diet shows metabolic and immune benefits that, according to a simulation, might translate into years of additional lifespan [1]. Fasting in disguise Caloric restriction is among the most powerful life-extending interventions in mice [2]. However, there is a lack
Meaningful Improvements in Human Trial For Sarcopenia
February 22, 2024
Rejuvenate Biomed has recently concluded a clinical trial for sarcopenia. The results have shown “meaningful improvements in muscle strength, function and fatigue resistance”. What is sarcopenia? Sarcopenia is an age-related progressive loss of muscle mass and strength that affects many older adults. This decline in muscle
A Nanoparticle Reduces Brain Inflammation in Mice
February 22, 2024
A recent preprint paper from researchers at Sachi Bio has described how this company’s technology can be used to alleviate brain inflammation in a mouse model. The problem of tau Along with the infamous amyloid beta, tau is well-known as a pathological factor in both Alzheimer’s
Educational Attainment Linked to Lower Mortality Risk
February 21, 2024
A systematic review and meta-analysis published in the Lancet suggests that more years of education is linked to reduced all-cause mortality in adults [1]. Benefits of education Educational attainment is associated with better health and improvements in some measurements of mortality. One example is parental education.
Rejuvenate Bio Develops Gene Therapy for Dog Arthritis
February 20, 2024
Rejuvenate Bio has announced a partnership with a leading animal health company to develop a gene therapy for canine osteoarthritis. The identity of the partnering global company is as yet unknown. This San Diego-based biotech was co-founded in 2017 by Professor George Church of Harvard Medical
How Individual Lifestyle Factors Affect Lifespan
February 20, 2024
A new study has reported that adopting more healthy lifestyle habits continuously lowers mortality risk, resulting in many years of added life expectancy [1]. The magnificent eight Lead a healthy lifestyle, and you will live longer. This sounds trivial, but it is important for geroscience to
Connecting Gut Metabolism to Grip Strength
February 19, 2024
In Aging, a team of researchers has outlined a possible relationship between low grip strength and compounds in the gut microbiome. The gut-muscle axis As these researchers note, previous work has described many of the various ways in which metabolism is related to age-related muscle dysfunction,
Solving Atherosclerosis: The Small but Mighty Molecule
February 19, 2024
Cyclarity Therapeutics is developing an affordable, plaque-busting small molecule that may be the cure for the world’s number one killer: cardiovascular disease. With human trials planned for this year, we decided that it was time to catch up with Cyclarity and its CEO of Scientific Affairs,
The Latest in Rapamycin Research on Humans
February 18, 2024
Reviewers have gone through the latest updates on studies featuring rapamycin and its derivatives in The Lancet Healthy Longevity. Testing a well-known longevity promoter Not many compounds actually extend life in healthy animals, but rapamycin is indeed one of them. These researchers report that its mechanism
New Drug Shows Promise Against Glioblastoma
February 16, 2024
Scientists have discovered a small molecule that effectively kills glioblastoma, a highly aggressive and untreatable brain cancer, in cellular cultures [1]. When acidic means deadly Despite scientists’ best efforts, some types of cancer remain almost as deadly as ever. This includes the dreaded glioblastoma, a type
How Aging Leads to a Gene Transcription Problem
February 15, 2024
In Nature Genetics, researchers have described how a defect in RNA transcription constitutes a previously undiscovered mechanism of aging. When the blueprint becomes harder to read Gene expression begins when a cell transcribes RNA from DNA protein codes. This process, like almost all others, is affected