Category: News
Rejuvenation Roundup January 2024
February 1, 2024
As work on epigenetic treatments continues, we continue to showcase all the novel research and possible therapies that might make several age-related diseases much more treatable. Here’s what happened in
Brain Cancer and Therapy May Lead to Brain Aging
January 31, 2024
In a recent study published in Aging Cell, researchers found similarities between glioblastoma and Alzheimer’s disease patients in their gene expression and protein profiles [1]. Brain tumors and neurocognitive dysfunction
Epicatechin Protects Rats from Myocardial Infarction
January 30, 2024
A new study suggests that the flavonoid epicatechin, found in chocolate, tea, and berries, provides robust protection against reperfusion injury in myocardial infarction [1]. Reperfusion injury: friendly fire Myocardial infarction
Epigenetic Reprogramming to Repair Genetic Damage
January 29, 2024
Steve Horvath, Vera Gorbunova, Alejandro Ocampo, and their team have used partial reprogramming to repair DNA damage in a mouse model. They published their findings in Frontiers in Aging. Building
CAR T Therapy Lowers Senescence, Improves Health in Mice
January 26, 2024
Scientists have created CAR T cells that target senescent cells. This approach alleviated metabolic dysfunction in mice [1]. Immunotherapy is not just for cancer Cellular senescence plays a complex and
Fasting and NSAIDs May Work the Same Way
January 25, 2024
In a new paper in Cell Reports, researchers have named a little-known lipid as a core reason why inflammation decreases with fasting and may also shed light on how non-steroidal
Different Risks for Men and Women’s Cardiovascular Health
January 24, 2024
In a recent paper published in Nutrients, the authors investigated longitudinal data regarding dietary and lifestyle factors that impact cardiovascular risk in males and females [1]. Cardiovascular disease risk factors
Plant Protein Is Associated with Lifelong Health
January 23, 2024
A new large cohort study suggests that protein might be healthier than some other nutrients and that plant protein is especially beneficial for lifelong health [1]. How much and from
Physical Activity May Decrease Disability-Related Mortality
January 22, 2024
Today in GeroScience, researchers have published an analysis of a cohort study, concluding that adherence to physical activity recommendations can mitigate the increased mortality associated with disability. Simply being able
A Better Environment May Ameliorate Early Aging
January 21, 2024
Publishing in Aging, researchers have reversed the early aging of prenatally harmed young mice by exposing them to a more enriched environment. Young organisms born old Newborn rodents from sleep-deprived
Google’s Chatbot Does Medical Interviews Better than Humans
January 19, 2024
Scientists at Google have created an AI chatbot for conducting medical interviews. It matched or surpassed human primary care practitioners on most criteria, including accuracy, politeness, and empathy [1]. AI,
Journal Club Episode 1 – 2024
January 19, 2024
The Journal Club, hosted by Dr. Oliver Medvedik, returns on February 2nd at 12:00 Eastern time on the Lifespan.io Facebook page. This time, we will be exploring The Information Theory
A Marker of Insulin Resistance Predicts Kidney Disease
January 18, 2024
A recent study published in GeroScience has investigated whether or not a common index of metabolic syndrome can be applied to chronic kidney disease (CKD). A common metric of diabetes
Combining Common Anti-Aging Interventions and Exercise
January 17, 2024
A review recently published in BMC Biology suggests that taking gerotherapeutics while exercising doesn’t have advantages over separate treatments [1]. Are two approaches better than one? Exercise is a well-established
Enhanced CAR T Cells Eradicate Multiple Cancers
January 17, 2024
Scientists have created improved CAR T cells that also express the cytokine IL-10. The new cells proved highly effective in mice and in a pilot human trial [1]. The promise
Rejuvenation Roundup January 2024
February 1, 2024
As work on epigenetic treatments continues, we continue to showcase all the novel research and possible therapies that might make several age-related diseases much more treatable. Here’s what happened in January. LEAF News Interviews Andrew Steele: “A Mindset Shift Is Required”: Andrew Steele is a physicist
Brain Cancer and Therapy May Lead to Brain Aging
January 31, 2024
In a recent study published in Aging Cell, researchers found similarities between glioblastoma and Alzheimer’s disease patients in their gene expression and protein profiles [1]. Brain tumors and neurocognitive dysfunction The majority of patients with brain tumors develop irreversible, progressive neurocognitive dysfunction, sometimes long after their
Epicatechin Protects Rats from Myocardial Infarction
January 30, 2024
A new study suggests that the flavonoid epicatechin, found in chocolate, tea, and berries, provides robust protection against reperfusion injury in myocardial infarction [1]. Reperfusion injury: friendly fire Myocardial infarction (heart attack) is the injury caused by complete or partial cessation of blood flow to a
Epigenetic Reprogramming to Repair Genetic Damage
January 29, 2024
Steve Horvath, Vera Gorbunova, Alejandro Ocampo, and their team have used partial reprogramming to repair DNA damage in a mouse model. They published their findings in Frontiers in Aging. Building a path to rejuvenation The researchers begin their paper by discussing these four well-known factors along
CAR T Therapy Lowers Senescence, Improves Health in Mice
January 26, 2024
Scientists have created CAR T cells that target senescent cells. This approach alleviated metabolic dysfunction in mice [1]. Immunotherapy is not just for cancer Cellular senescence plays a complex and context-dependent role. It is important in organismal development and wound healing, but as the number of
Fasting and NSAIDs May Work the Same Way
January 25, 2024
In a new paper in Cell Reports, researchers have named a little-known lipid as a core reason why inflammation decreases with fasting and may also shed light on how non-steroidal anti-inflammatory drugs (NSAIDs) work. Why high-calorie diets increase inflammation Previous research has identified the core reason
Different Risks for Men and Women’s Cardiovascular Health
January 24, 2024
In a recent paper published in Nutrients, the authors investigated longitudinal data regarding dietary and lifestyle factors that impact cardiovascular risk in males and females [1]. Cardiovascular disease risk factors Aging, particularly vascular aging, is a major risk factor for cardiovascular diseases (CVD) [2]. Previous research
Plant Protein Is Associated with Lifelong Health
January 23, 2024
A new large cohort study suggests that protein might be healthier than some other nutrients and that plant protein is especially beneficial for lifelong health [1]. How much and from what source? The ideal amount of dietary protein has always been a subject of significant scientific
Physical Activity May Decrease Disability-Related Mortality
January 22, 2024
Today in GeroScience, researchers have published an analysis of a cohort study, concluding that adherence to physical activity recommendations can mitigate the increased mortality associated with disability. Simply being able to live In this paper, disability refers to impediments to the basic activities of daily living
A Better Environment May Ameliorate Early Aging
January 21, 2024
Publishing in Aging, researchers have reversed the early aging of prenatally harmed young mice by exposing them to a more enriched environment. Young organisms born old Newborn rodents from sleep-deprived mothers have conditions that are biologically similar to the processes of aging. One rat study found
Google’s Chatbot Does Medical Interviews Better than Humans
January 19, 2024
Scientists at Google have created an AI chatbot for conducting medical interviews. It matched or surpassed human primary care practitioners on most criteria, including accuracy, politeness, and empathy [1]. AI, MD Before doctors begin treating, they do a lot of talking. The initial conversation with the
Journal Club Episode 1 – 2024
January 19, 2024
The Journal Club, hosted by Dr. Oliver Medvedik, returns on February 2nd at 12:00 Eastern time on the Lifespan.io Facebook page. This time, we will be exploring The Information Theory of Aging, a new paper that includes Dr. David Sinclair among its authors. We will taking
A Marker of Insulin Resistance Predicts Kidney Disease
January 18, 2024
A recent study published in GeroScience has investigated whether or not a common index of metabolic syndrome can be applied to chronic kidney disease (CKD). A common metric of diabetes The triglyceride-glucose (TyG) index, which is calculated from fasting triglyceride and glucose, is used as a
Combining Common Anti-Aging Interventions and Exercise
January 17, 2024
A review recently published in BMC Biology suggests that taking gerotherapeutics while exercising doesn’t have advantages over separate treatments [1]. Are two approaches better than one? Exercise is a well-established intervention that ameliorates several aspects of aging. Similarly, other research suggests that certain drugs, known as
Enhanced CAR T Cells Eradicate Multiple Cancers
January 17, 2024
Scientists have created improved CAR T cells that also express the cytokine IL-10. The new cells proved highly effective in mice and in a pilot human trial [1]. The promise and the limitations Chimeric antigen receptor (CAR) T cells are among the most promising treatments in