Lifespan Research Institute

Category: News

Food restriction

Aging Might Blunt the Effects of Fasting

Scientists have found that in killifish, old age is associated with a dampened response to fasting and identified the protein that might be responsible. A similar mechanism might exist in

Genetic damage

Some HIV-Fighting Drugs May Also Fight Aging

Publishing in Ageing Research Reviews, a team of researchers including Vera Gorbunova has described how a class of drugs originally used to treat HIV might be used to affect some

Two apples one arrow

Dual-Purpose Molecular Targets for Cancer and Aging

A new study published in Aging Cell applied an artificial intelligence target discovery platform to aid in identifying potential dual-purpose targets for anti-aging and anti-cancer treatments [1]. Killing two birds

David Barzilai

An Anonymous Longevity Enthusiast Unmasks Himself

A prolific anonymous poster who became popular in the longevity community has revealed his identity, and other longevity luminaries have chimed in. The anonym Anonymity is seldom practiced in the

Chromatin

Pushing Forward on Understanding Cellular Decline

Researchers publishing in Nature Aging have investigated one of the core biological reasons behind the decline of stem cells’ ability to proliferate. Heterochromatin and euchromatin The genetic component of cells

Dietary choices

Promoting Health and Longevity Through Diet

A review published in the Journal of Internal Medicine summarized current knowledge on the impact of dietary factors on chronic diseases and longevity [1]. Restrict calories, live healthier and longer

Rat looking at camera

Targeting Metabolism to Protect Against Stroke

Japanese researchers publishing in Aging have described how improving the AMPK metabolic pathway improves outcomes in a rat model of stroke. Targeting metabolism directly This paper begins with a look

Gift giving

Cells Regularly Donate Mitochondria to One Another

In a review published in Nature, researchers have explained how and why cells transfer mitochondria to one another, proposing that this transfer allows organisms to be more resilient against energy deficiencies.

Extra Virgin Olive Oil

Olive Oil Fights Cognitive Decline in Clinical Trials

In a recent review published in Frontiers in Nutrition, the researchers reviewed studies linking olive oil consumption to cognitive performance [1]. Dietary interventions to improve cognition As life expectancy rises,

Food restriction

Aging Might Blunt the Effects of Fasting

Scientists have found that in killifish, old age is associated with a dampened response to fasting and identified the protein that might be responsible. A similar mechanism might exist in humans [1]. Fast less furious Various fasting regimens are thought to confer health and longevity benefits

Genetic damage

Some HIV-Fighting Drugs May Also Fight Aging

Publishing in Ageing Research Reviews, a team of researchers including Vera Gorbunova has described how a class of drugs originally used to treat HIV might be used to affect some of the hallmarks of aging. Inhibiting DNA changes DNA transcription, which transfers DNA code into the

Two apples one arrow

Dual-Purpose Molecular Targets for Cancer and Aging

A new study published in Aging Cell applied an artificial intelligence target discovery platform to aid in identifying potential dual-purpose targets for anti-aging and anti-cancer treatments [1]. Killing two birds with one stone Aging, as is the case with many diseases, is a risk factor for

Young People More Vulnerable to Atherosclerosis Risk Factors

A new study suggests that increases in LDL cholesterol and systolic blood pressure elevate the risk of atherosclerosis progression more in younger than in older people. The good news is that this can be reversed [1]. Creeping atherosclerosis Atherosclerosis is a major risk factor for cardiovascular

Basal cell carcinoma

Skin Collagen Loss Makes It Easier For Cancer To Grow

A new paper published in Nature has described how the aging extracellular matrix makes it easier for cancer to grow. When cancer is skin deep Under normal circumstances, we lose and regain skin cells constantly. Old skin flakes away, and stem cells constantly divide and differentiate

David Barzilai

An Anonymous Longevity Enthusiast Unmasks Himself

A prolific anonymous poster who became popular in the longevity community has revealed his identity, and other longevity luminaries have chimed in. The anonym Anonymity is seldom practiced in the longevity community. Everyone knows everyone, and on social media, most people use their real names rather

Chromatin

Pushing Forward on Understanding Cellular Decline

Researchers publishing in Nature Aging have investigated one of the core biological reasons behind the decline of stem cells’ ability to proliferate. Heterochromatin and euchromatin The genetic component of cells is comprised of two main parts: heterochromatin and euchromatin. Heterochromatin is largely silent, as it is

Meat versus plants

Plant-Based Alternatives Are Associated With Less Disease

A new meta-analysis has found that in many cases, switching from an animal product to a plant-based alternative is associated with less cardiovascular, diabetes, and all-cause mortality risk [1]. Supplant with plant? Whether a completely or mostly plant-based diet is good for you has been the

Brain COVID

Senolytics May Work Against Long COVID in the Brain

A new publication in Nature Aging has used organoids and model mice to discover that senolytics may be effective treatments for neurodegeneration caused by long COVID. A link between COVID-19 and cellular senescence Post-acute infection syndromes (PAISes) are caused by a variety of viral and bacterial

Dietary choices

Promoting Health and Longevity Through Diet

A review published in the Journal of Internal Medicine summarized current knowledge on the impact of dietary factors on chronic diseases and longevity [1]. Restrict calories, live healthier and longer The choice of what someone eats obviously has a profound impact on that person’s health, but

Fang feng

Saposhnikovia Root Extract Improves Tendon Repair

A new study has identified a molecule found in Saposhnikovia root as a potent mediator of tendon regeneration in rats. The results were also replicated in human cells [1]. Aging does not spare tendons Like with many tissues, the health of tendons, which are central to

Rat looking at camera

Targeting Metabolism to Protect Against Stroke

Japanese researchers publishing in Aging have described how improving the AMPK metabolic pathway improves outcomes in a rat model of stroke. Targeting metabolism directly This paper begins with a look back at previous research on the focus of this study, 5′-adenosine monophosphate-activated protein kinase (AMPK). This

Food choices

Mediterranean, Keto, and Plant-Based Diets Vs. Cancer

A new review summarizes what we know about the Mediterranean, keto, and plant-based diets and their effects on cancer risk and progression [1]. Diet matters Since the War on Cancer began in the early 1970s, science has made giant strides in understanding and treating cancer. However,

Gift giving

Cells Regularly Donate Mitochondria to One Another

In a review published in Nature, researchers have explained how and why cells transfer mitochondria to one another, proposing that this transfer allows organisms to be more resilient against energy deficiencies. A relatively recent discovery It was not until 2006 when a team of researchers realized that

Extra Virgin Olive Oil

Olive Oil Fights Cognitive Decline in Clinical Trials

In a recent review published in Frontiers in Nutrition, the researchers reviewed studies linking olive oil consumption to cognitive performance [1]. Dietary interventions to improve cognition As life expectancy rises, there is an increasing number of elderly people, many of whom struggle with cognitive decline. However,