Category: News
Twin Study: Healthy Vegan Diet Beats Healthy Omnivorous Diet
December 8, 2023
In a randomized controlled trial, eight weeks of healthy vegan eating, but not of healthy omnivorous eating, led to weight loss and significant improvements in LDL cholesterol and insulin levels
Astaxanthin and Meclizine Extend Lifespan in Mice
December 7, 2023
Scientists in the Intervention Testing Program have found that the antioxidant astaxanthin and the seasickness medication meclizine, both sold over the counter, significantly extend median lifespan in mice [1]. Astaxanthin
A Microvesicle Hydrogel to Treat Arthritis
December 7, 2023
In the Journal of Nanobiotechnology, researchers have found that embedding microvesicles in a slow-release hydrogel may be an effective treatment for osteoarthritis. A line of inquiry begins to bear fruit
Caloric Restriction Associated With Reduced Senescence
December 6, 2023
New research in Aging Cell has identified senescence-associated biomarkers whose levels are altered by caloric restriction in humans [1]. Slowing down senescence with fewer calories Multiple animal studies have found
Was Mammals’ Longevity Shaped by Living Among Dinosaurs?
December 5, 2023
A prominent geroscientist suggests that more than 100 million years of saurian domination might have deprived mammals of longevity-promoting traits that are found in today’s reptiles [1]. The longevity bottleneck
Pre-Senescent Cells May Be Damaging and Treatable
December 4, 2023
Researchers have described an intermediary state between senescent and young cells, the inflammatory problems caused by these cells, and how young cells secrete a protein that may alleviate these problems.
Mechanically Reprogrammed Fibroblasts for Skin Rejuvenation
December 4, 2023
Scientists have found a way to reprogram fibroblasts without chemicals by culturing them on a surface with specific mechanical properties. Transplanted into aged skin, those cells boosted rejuvenation in a
Longevity and DeSci Recap – November 2023
December 1, 2023
Thanks for joining us again for the latest edition of the Longevity and DeSci Recap. This month’s highlights include fantastic conferences, such as the Rejuvenation Startup Summit 2024 in Berlin,
Healthy Diet Linked to Massive Gains in Life Expectancy
December 1, 2023
A new study has found that switching to longevity-associated dietary patterns was associated with up to a 10-year gain in life expectancy for 40-year-olds and up to a 3.4-year gain
Rejuvenation Roundup November 2023
December 1, 2023
As researchers and biotech companies continue to work on the therapies and technologies that may let people live longer lives, much other research tells us about the lifestyle habits that
Running Is Associated With Better Health Biomarkers
November 30, 2023
In a recent publication in PLOS One, researchers have described the metabolic effects on running in generally healthy people. A lack of activity is a known risk factor This paper
Music Therapy for Treating Alzheimer’s Disease
November 29, 2023
The authors of a new review have analyzed randomized controlled trials that evaluated the impact of music therapy on the cognitive functions of people with Alzheimer’s [1]. Music to Alzheimer’s
Isoleucine Restriction Boosts Lifespan in Mice
November 28, 2023
A new study reports a massive 33% increase in median lifespan in male genetically heterogeneous mice following prolonged isoleucine restriction [1]. Not all calories are created equal Caloric restriction is
Mammals Accumulate Epigenetic Noise With Age
November 27, 2023
In Nature Communications, researchers have explained how epigenetic drift and disorder are associated with shorter lifespans across species. When randomness is a problem We have previously reported on research demonstrating
B12 Is a Limiting Factor for Induced Cellular Plasticity
November 27, 2023
Due to Thanksgiving happening on our usual timeslot, the Journal Club returns on December 1st at 12 Eastern. The show will be livestreamed on the Lifespan.io Facebook channel and hosted
Twin Study: Healthy Vegan Diet Beats Healthy Omnivorous Diet
December 8, 2023
In a randomized controlled trial, eight weeks of healthy vegan eating, but not of healthy omnivorous eating, led to weight loss and significant improvements in LDL cholesterol and insulin levels in a middle-aged twin study [1]. A tale of two diets Most of our knowledge about
Astaxanthin and Meclizine Extend Lifespan in Mice
December 7, 2023
Scientists in the Intervention Testing Program have found that the antioxidant astaxanthin and the seasickness medication meclizine, both sold over the counter, significantly extend median lifespan in mice [1]. Astaxanthin and meclizine are in, but fisetin is out The Intervention Testing Program (ITP) has existed for
A Microvesicle Hydrogel to Treat Arthritis
December 7, 2023
In the Journal of Nanobiotechnology, researchers have found that embedding microvesicles in a slow-release hydrogel may be an effective treatment for osteoarthritis. A line of inquiry begins to bear fruit Researchers have repeatedly found that the extracellular vesicles (EVs) released by stem cells, particularly mesenchymal stem
Caloric Restriction Associated With Reduced Senescence
December 6, 2023
New research in Aging Cell has identified senescence-associated biomarkers whose levels are altered by caloric restriction in humans [1]. Slowing down senescence with fewer calories Multiple animal studies have found that reducing caloric intake without causing malnutrition (caloric restriction) has great lifespan-extending potential and can delay
Was Mammals’ Longevity Shaped by Living Among Dinosaurs?
December 5, 2023
A prominent geroscientist suggests that more than 100 million years of saurian domination might have deprived mammals of longevity-promoting traits that are found in today’s reptiles [1]. The longevity bottleneck Today, mammals rule the world, but, sadly, we only have an average of 80 years to
Pre-Senescent Cells May Be Damaging and Treatable
December 4, 2023
Researchers have described an intermediary state between senescent and young cells, the inflammatory problems caused by these cells, and how young cells secrete a protein that may alleviate these problems. What happens before senescence? As these researchers note, the problems with senescent cells are very well-known
Mechanically Reprogrammed Fibroblasts for Skin Rejuvenation
December 4, 2023
Scientists have found a way to reprogram fibroblasts without chemicals by culturing them on a surface with specific mechanical properties. Transplanted into aged skin, those cells boosted rejuvenation in a human tissue model [1]. We’ve all got skin in the game Skin aging might not be
Longevity and DeSci Recap – November 2023
December 1, 2023
Thanks for joining us again for the latest edition of the Longevity and DeSci Recap. This month’s highlights include fantastic conferences, such as the Rejuvenation Startup Summit 2024 in Berlin, the Vitalia event in Roatan, and the large-scale Longevity Med Summit in Lisbon, along with many
Healthy Diet Linked to Massive Gains in Life Expectancy
December 1, 2023
A new study has found that switching to longevity-associated dietary patterns was associated with up to a 10-year gain in life expectancy for 40-year-olds and up to a 3.4-year gain for 70-year-olds [1]. Eat your way to longevity Since the early twentieth century, average human life
Rejuvenation Roundup November 2023
December 1, 2023
As researchers and biotech companies continue to work on the therapies and technologies that may let people live longer lives, much other research tells us about the lifestyle habits that people are doing to lengthen them – or shorten them – in the meantime. Here’s what
Running Is Associated With Better Health Biomarkers
November 30, 2023
In a recent publication in PLOS One, researchers have described the metabolic effects on running in generally healthy people. A lack of activity is a known risk factor This paper begins with warnings against sedentary behavior, citing one study reporting that it is responsible for approximately
Music Therapy for Treating Alzheimer’s Disease
November 29, 2023
The authors of a new review have analyzed randomized controlled trials that evaluated the impact of music therapy on the cognitive functions of people with Alzheimer’s [1]. Music to Alzheimer’s patients’ ears Current pharmacology lacks a long-term method of effectively managing Alzheimer’s disease symptoms. Therefore, researchers
Isoleucine Restriction Boosts Lifespan in Mice
November 28, 2023
A new study reports a massive 33% increase in median lifespan in male genetically heterogeneous mice following prolonged isoleucine restriction [1]. Not all calories are created equal Caloric restriction is the most powerful life-extending intervention in rodents and primates [2], but the needed magnitude (about 30%
Mammals Accumulate Epigenetic Noise With Age
November 27, 2023
In Nature Communications, researchers have explained how epigenetic drift and disorder are associated with shorter lifespans across species. When randomness is a problem We have previously reported on research demonstrating that epigenetic clocks are most likely to be measuring noise. This paper builds on that concept,
B12 Is a Limiting Factor for Induced Cellular Plasticity
November 27, 2023
Due to Thanksgiving happening on our usual timeslot, the Journal Club returns on December 1st at 12 Eastern. The show will be livestreamed on the Lifespan.io Facebook channel and hosted by Dr. Oliver Medvedik. This month, we will be taking a look at a new paper