Lifespan Research Institute

Category: News

Elderly Alcohol

Epigenetic Age Accelerated By Drinking Alcohol

A new study has found that higher levels of long-term alcohol consumption are associated with a larger gap between the person’s biological and chronological age, but not in the young

Ancient clock

Predicting Future Frailty with an Epigenetic Clock

An accepted manuscript in the Journals of Gerontology has described how a third-generation epigenetic clock is a predictor  of future frailty. Are epigenetic and physiological metrics connected? This paper begins

Two rats

Hyperbaric Oxygen Therapy Improves Bone Health in Rats

Scientists have demonstrated that hyperbaric oxygen therapy can reverse some aspects of bone deterioration caused by aging and obesity in rats [1]. Under pressure Hyperbaric oxygen therapy (HBOT) involves placing

Longevity Desci Oct 2023

Longevity and DeSci Recap – October 2023

Welcome back to the latest edition of the Longevity and DeSci Recap. Here, you’ll discover the latest interviews, insights, and research in the longevity tech sphere over the past month,

Rejuvenation Roundup October 2023

Rejuvenation Roundup October 2023

As we head towards the end of fall, biotechnology companies have made greater investments into rejuvenation as research advancements have shown what might be possible. Here’s what’s happened in October.

Capillaries

A Reason Brain Protection Fails As We Age

Researchers publishing in GeroScience have discovered the molecular mechanisms through which fibrinogen, a protein that increases with aging, causes toxic compounds to more easily leak into the brain. The deteriorating

Resveratrol foods

Resveratrol May Improve Mitochondrial Function

According to a review published in Food Science and Human Wellness, resveratrol has a positive impact on mitochondrial dysfunction, one of the hallmarks of aging. A hallmark with downstream consequences

Prostate enlargement

Prostate Enlargement and Metabolic Syndrome Linked

Researchers publishing in Aging have explained a relationship between inflammation, metabolic syndrome, and prostate enlargement. Not so benign Benign prostatic hyperplasia (BPH) is only called ‘benign’ to differentiate it from

Older man exercising

Lifestyle Interventions Against Cellular Senescence

A new review summarizes our knowledge about lifestyle interventions, such as exercise, healthy diet, and good sleep, that can possibly reduce cellular senescence [1]. What do we do with a senescent cell? Senescent cells play a complex role. In some contexts, such as early organismal development

Tweaking the Growth of Stem Cells for Better Therapies

Researchers publishing in ACS Nano have described how culturing stem cells on nanogratings instead of flat substrates changes the effects of the extracellular vesicles (EVs) they send, potentially paving the way to a new system of therapies. When signaling is critical Many of the effects of

Elderly Alcohol

Epigenetic Age Accelerated By Drinking Alcohol

A new study has found that higher levels of long-term alcohol consumption are associated with a larger gap between the person’s biological and chronological age, but not in the young [1]. Don’t drink and age It is common knowledge that excessive drinking can be quite harmful

Ancient clock

Predicting Future Frailty with an Epigenetic Clock

An accepted manuscript in the Journals of Gerontology has described how a third-generation epigenetic clock is a predictor  of future frailty. Are epigenetic and physiological metrics connected? This paper begins with an examination of two different methods of measuring aging processes. The first is the well-known

Two rats

Hyperbaric Oxygen Therapy Improves Bone Health in Rats

Scientists have demonstrated that hyperbaric oxygen therapy can reverse some aspects of bone deterioration caused by aging and obesity in rats [1]. Under pressure Hyperbaric oxygen therapy (HBOT) involves placing the patient in a chamber with elevated levels of oxygen and atmospheric pressure. HBOT has been

Longevity Desci Oct 2023

Longevity and DeSci Recap – October 2023

Welcome back to the latest edition of the Longevity and DeSci Recap. Here, you’ll discover the latest interviews, insights, and research in the longevity tech sphere over the past month, and learn more about blockchain, DAOs, cryptocurrency, DeSci, and events. This October saw ExcepGEN, a genetic

Lab rats

Bacteria from Alzheimer’s Patients Induced Symptoms in Rats

New research published in Brain investigated the influence of fecal microbiota transplants from Alzheimer’s patients on cognitive function and neurogenesis in rats and human cell cultures [1]. Microbiota-gut-brain axis There is a growing body of research reporting changes to the composition and metabolites in the microbiomes

Rejuvenation Roundup October 2023

Rejuvenation Roundup October 2023

As we head towards the end of fall, biotechnology companies have made greater investments into rejuvenation as research advancements have shown what might be possible. Here’s what’s happened in October. LEAF News Help Us Solve Aging With Cryptocurrency: If you want to contribute to Lifespan.io and

Exercising Obesity

Metabolically Healthy Obesity Still Increases Diabetes Risk

A new study suggests that while it is possible to be both obese and healthy, this phenotype considerably increases the risk of getting diabetes, mainly because it is hard to maintain [1]. Chubby and happy? Obesity is a known comorbidity in numerous chronic conditions, including age-related

Capillaries

A Reason Brain Protection Fails As We Age

Researchers publishing in GeroScience have discovered the molecular mechanisms through which fibrinogen, a protein that increases with aging, causes toxic compounds to more easily leak into the brain. The deteriorating blood-brain barrier In the brain, the microvessels (MVs) that are responsible for carrying blood to neurons

Happy pig

Plasma from Young Pigs Halves Old Rats’ Epigenetic Age

A new study used a plasma fraction from young pigs to robustly reduce the biological age of old rats. This could potentially open doors to rejuvenation in humans [1]. The blood connection People have been trying to use young blood to rejuvenate old organisms for millennia,

Resveratrol foods

Resveratrol May Improve Mitochondrial Function

According to a review published in Food Science and Human Wellness, resveratrol has a positive impact on mitochondrial dysfunction, one of the hallmarks of aging. A hallmark with downstream consequences The reviewers begin this paper by discussing various chronic and age-related diseases associated with mitochondrial dysfunction,

Sleeping mice

Intermittent Fasting Partially Offsets Alzheimer’s in Mice

Scientists have found that intermittent fasting can ameliorate Alzheimer’s in mice by improving sleep patterns [1]. Time to eat, time to fast Time-restricted eating, also referred to as intermittent fasting (IF), can take different shapes, such as the one-meal-a-day regimen, alternate-day fasting, or 16/8, in which

Prostate enlargement

Prostate Enlargement and Metabolic Syndrome Linked

Researchers publishing in Aging have explained a relationship between inflammation, metabolic syndrome, and prostate enlargement. Not so benign Benign prostatic hyperplasia (BPH) is only called ‘benign’ to differentiate it from another well-known cause of prostate enlargement: prostate cancer. BPH is known to lead to bladder obstruction

Cannabinoids

Cannabinoid Therapy as a Treatment for Alzheimer’s Disease

The authors of a recent paper have reviewed the literature regarding the potential of cannabinoids to treat Alzheimer’s disease [1]. The endocannabinoid system and Alzheimer’s disease Aging is a well-known risk factor for Alzheimer’s, and more than 50% of people over 85 are expected to suffer