Category: News
Figuring Out Why Stem Cells Won’t Build Bone
August 21, 2023
Researchers publishing in Aging have uncovered some of the molecular mechanisms behind why mesenchymal stem cells (MSCs) do and don’t differentiate into bone-building osteoblasts, unlocking a potential new approach to
Join us for Journal Club August 2023
August 20, 2023
The Journal Club for August returns live to the Lifespan.io Facebook channel on September 5th at 12:00 Eastern hosted by Dr. Oliver Medvedik. This time we are taking a look
Antioxidants Rescue Cognitive Decline in Mice
August 18, 2023
Scientists have found that EGCG and curcumin, two well-known antioxidants, are effective both alone and especially in combination in a mouse model of cognitive decline induced by oxidative stress [1].
Biomarker Study Returns Surprising Results
August 17, 2023
Researchers publishing in Biogerontology have tested multiple biomarkers in an effort to use them as proxies for aging, and some of their findings were surprising. A simple study with direct
Flavonoid Consumption Correlates With Less Biological Aging
August 16, 2023
Researchers investigated how much the consumption of flavonoids impacts the biological age of the heart, kidney, liver, and whole body [1]. Chronological age, biological age, and diet Chronological age only
Extracellular Vesicles from Stem Cells Reverse Senescence
August 15, 2023
Scientists have found that bubbles secreted by embryonic stem cells counter cellular senescence, in large part due to just two tiny snippets of RNA [1]. Helpful bubbles Extracellular vesicles (EVs)
Restoring Helper Cell Function to Fight Alzheimer’s
August 14, 2023
In a study published in Cell Stem Cell, researchers have investigated a way to repopulate the brain with functional cells in order to fight back against Alzheimer’s disease. A gene
Study: Vegetarians Have Higher Risk of Hip Fracture
August 11, 2023
Studying a large British cohort, scientists have found that vegetarians have an increased risk of hip fracture compared to regular meat eaters, but pescatarians and occasional meat eaters do not
Inflammation as a Biomarker of Mortality
August 10, 2023
In a paper published in Geroscience, researchers have developed a metric of systemic inflammation and used it to estimate mortality, finding that it performs better than epigenetic clocks. Evaluating a
New Senolytics from Artificial Intelligence
August 9, 2023
Recent research published in Nature Communications has used machine learning algorithms to find new compounds that can eliminate senescent cells [1]. Searching for new senolytics Senolytics are molecules that destroy
Liquid Metal Nanoparticles Eradicate Colon Cancer in Mice
August 9, 2023
Scientists have combined gallium nanoparticles with immunotherapy agents to deliver a decisive blow to colon cancer tumors in mice [1]. Cancer, you are terminated Most moviegoers are familiar with the
Artificial Sweeteners Associated with Fat, Weight Gain
August 8, 2023
A longitudinal analysis of a large cohort suggests an association between artificial sweetener intake and several markers of adiposity, such as visceral fat [1]. Safely sweet? Artificial sweeteners were invented
The Inflammatory Pathway to Brain Damage
August 7, 2023
Scientists publishing in Nature have explained a key pathway that leads to immune dysfunction and neurodegeneration in aging. Feeling the STING Throughout this paper, the researchers cite other papers demonstrating
Happiness and Lifespan Are Strongly Linked
August 6, 2023
Researchers publishing in BMC Geriatrics have found that people who reported being happy were considerably more likely to live longer than people who were not. Conflicting previous research The relationship
Analysis: Isometric Exercises Are Best for Blood Pressure
August 4, 2023
In a new expansive meta-analysis comparing several types of exercise, isometric exercises, which include wall squats and planks, were linked to the biggest decrease in blood pressure [1]. Lowering the
Figuring Out Why Stem Cells Won’t Build Bone
August 21, 2023
Researchers publishing in Aging have uncovered some of the molecular mechanisms behind why mesenchymal stem cells (MSCs) do and don’t differentiate into bone-building osteoblasts, unlocking a potential new approach to osteoporosis. A matter of cellular fate MSCs are downstream of pluripotent stem cells: they can differentiate
Join us for Journal Club August 2023
August 20, 2023
The Journal Club for August returns live to the Lifespan.io Facebook channel on September 5th at 12:00 Eastern hosted by Dr. Oliver Medvedik. This time we are taking a look at a paper where researchers have transfered a lifespan and healthspan boosting mechanism from the naked
Antioxidants Rescue Cognitive Decline in Mice
August 18, 2023
Scientists have found that EGCG and curcumin, two well-known antioxidants, are effective both alone and especially in combination in a mouse model of cognitive decline induced by oxidative stress [1]. Not the usual stress Oxidative stress results mostly from molecules called reactive oxygen species (ROS), which
Biomarker Study Returns Surprising Results
August 17, 2023
Researchers publishing in Biogerontology have tested multiple biomarkers in an effort to use them as proxies for aging, and some of their findings were surprising. A simple study with direct measurements Unlike other association studies that are used to evaluate biomarkers of aging, this study did
Flavonoid Consumption Correlates With Less Biological Aging
August 16, 2023
Researchers investigated how much the consumption of flavonoids impacts the biological age of the heart, kidney, liver, and whole body [1]. Chronological age, biological age, and diet Chronological age only refers to the number of years that have passed, but biological age refers to the lasting
Extracellular Vesicles from Stem Cells Reverse Senescence
August 15, 2023
Scientists have found that bubbles secreted by embryonic stem cells counter cellular senescence, in large part due to just two tiny snippets of RNA [1]. Helpful bubbles Extracellular vesicles (EVs) are membrane-bound tiny bubbles that are loaded with various molecular cargo, such as proteins, DNA, or
Restoring Helper Cell Function to Fight Alzheimer’s
August 14, 2023
In a study published in Cell Stem Cell, researchers have investigated a way to repopulate the brain with functional cells in order to fight back against Alzheimer’s disease. A gene with a microglial function Various allelles of the apolipoprotein E (APOE) genes are well-known for their
Study: Vegetarians Have Higher Risk of Hip Fracture
August 11, 2023
Studying a large British cohort, scientists have found that vegetarians have an increased risk of hip fracture compared to regular meat eaters, but pescatarians and occasional meat eaters do not [1]. Diet and brittle bones Hip fracture is one of the injuries most associated with aging.
Inflammation as a Biomarker of Mortality
August 10, 2023
In a paper published in Geroscience, researchers have developed a metric of systemic inflammation and used it to estimate mortality, finding that it performs better than epigenetic clocks. Evaluating a danger This paper begins with familiar discussions about inflammaging and epigenetic clocks, tools that use DNA
New Senolytics from Artificial Intelligence
August 9, 2023
Recent research published in Nature Communications has used machine learning algorithms to find new compounds that can eliminate senescent cells [1]. Searching for new senolytics Senolytics are molecules that destroy senescent cells. Only a small number of such molecules have been identified, and only two have
Liquid Metal Nanoparticles Eradicate Colon Cancer in Mice
August 9, 2023
Scientists have combined gallium nanoparticles with immunotherapy agents to deliver a decisive blow to colon cancer tumors in mice [1]. Cancer, you are terminated Most moviegoers are familiar with the liquid metal T-1000 from the Terminator series, and everyone knows about mercury, a liquid metal that
Artificial Sweeteners Associated with Fat, Weight Gain
August 8, 2023
A longitudinal analysis of a large cohort suggests an association between artificial sweetener intake and several markers of adiposity, such as visceral fat [1]. Safely sweet? Artificial sweeteners were invented to provide a healthier alternative to sugar and other high-calorie sweeteners, especially in the wake of
The Inflammatory Pathway to Brain Damage
August 7, 2023
Scientists publishing in Nature have explained a key pathway that leads to immune dysfunction and neurodegeneration in aging. Feeling the STING Throughout this paper, the researchers cite other papers demonstrating a cause-and-effect relationship between initial damage and long-term effects. Perturbed mitochondria release their mitochondrial DNA (mtDNA)
Happiness and Lifespan Are Strongly Linked
August 6, 2023
Researchers publishing in BMC Geriatrics have found that people who reported being happy were considerably more likely to live longer than people who were not. Conflicting previous research The relationship between happiness and health, even controlling for other relevant factors, has been frequently confirmed and occasionally
Analysis: Isometric Exercises Are Best for Blood Pressure
August 4, 2023
In a new expansive meta-analysis comparing several types of exercise, isometric exercises, which include wall squats and planks, were linked to the biggest decrease in blood pressure [1]. Lowering the pressure As is very well-known, exercise confers numerous health benefits, including age-related benefits, and it has