Lifespan Research Institute

Category: News

Smoking mouse

Repairing the Long-Term Damage of Smoking

Researchers publishing in Aging Cell have described how treating the increased senescent cell burden that comes with cigarette smoke exposure can repair some of the damage. Senescent cells and COPD

DNA

Finding The Genes for Longevity in Mammals

Researchers have analyzed the activity of genes in the livers, kidneys, and brains of over a hundred mammals and found genes that are consistently associated with longevity [1]. The search

Rejuvenating Cells Using A New Small Molecule Approach

A team led by renowned Harvard geroscientists David Sinclair and Vadim Gladyshev has reported successful chemically induced partial cellular reprogramming in vitro. The researchers have also developed a novel cellular

sorting

Making Genetically Engineered Stem Cells Viable

Researchers publishing in Cell Stem Cell have announced a new method of accurately and rapidly cloning genetically engineered stem cells. CRISPR is still imperfect While the accuracy of genetic modification

Senolytics Restore Regeneration in Killifish

Researchers publishing in npj regenerative medicine have found that destroying senescent cells through a well-known senolytic combination gives older killifish back some of their regenerative abilities. Regeneration, for a while

Elderly walking

Better Health in Older Adults, One Step at a Time

Research published in Experimental Gerontology suggests that even smaller amounts of daily physical activity can benefit people over 60 [1]. Cardiometabolic health and physical activity The positive influence of exercise

The Journal Club is a monthly livestream hosted by Dr. Oliver Medvedik which covers the latest aging research papers.

Journal Club July 2023 – Zoom Details Within

The Journal Club returns on 25th July at 12:00 Eastern time to the Lifespan.io Facebook channel. Editing mitochondrial DNA (mtDNA) has long been a challenge, and systems such as CRISPR,

The Journal Club is a monthly livestream hosted by Dr. Oliver Medvedik which covers the latest aging research papers.

Editing Mitochondrial DNA

The Journal Club returns on 25th July at 12:00 Eastern time to the Lifespan.io Facebook channel. Editing mitochondrial DNA (mtDNA) has long been a challenge and systems such as CRISPR,

Fedichev Interview

Peter Fedichev Explains His Theory of Aging

Peter Fedichev, co-founder and CEO of Gero, is a relative newcomer to the field of geroscience with a background in physics and not in biology. However, Peter has firmly established

Creatine

Creatine on the Brain: A Review

A review recently published in Sports Medicine has discussed a considerable number of research papers that describe the effects of the muscle-building supplement creatine on the brain. Broadening the studies

Smoking mouse

Repairing the Long-Term Damage of Smoking

Researchers publishing in Aging Cell have described how treating the increased senescent cell burden that comes with cigarette smoke exposure can repair some of the damage. Senescent cells and COPD Chronic obstructive pulmonary disorder (COPD) and idiopathic pulmonary fibrosis (IPF), both of which are well-known consequences

Lifespan io Editorial

Ending Age-Related Diseases 2023 is Almost Here!

  Summer is in full swing, and our most important event of the year draws near. In this special edition of our editorial, we want to update you on our conference and what we have in store for you this year. Can we turn back our

DNA

Finding The Genes for Longevity in Mammals

Researchers have analyzed the activity of genes in the livers, kidneys, and brains of over a hundred mammals and found genes that are consistently associated with longevity [1]. The search for longevity-associated genes Between the shortest-living and the longest-living mammal, there is a more than 100-fold

Rejuvenating Cells Using A New Small Molecule Approach

A team led by renowned Harvard geroscientists David Sinclair and Vadim Gladyshev has reported successful chemically induced partial cellular reprogramming in vitro. The researchers have also developed a novel cellular rejuvenation assay [1]. Smaller than proteins Complete cellular reprogramming using the Yamanaka factors was first accomplished

sorting

Making Genetically Engineered Stem Cells Viable

Researchers publishing in Cell Stem Cell have announced a new method of accurately and rapidly cloning genetically engineered stem cells. CRISPR is still imperfect While the accuracy of genetic modification through the well-known CRISPR/Cas9 system continues to improve, the technology remains imperfect. Small mistakes were initially

Aerobic & Resistance Training Impact Skin Aging Differently

According to a new study published in Nature Scientific Reports, while both aerobic and resistance exercise improve some aspects of skin aging, only the latter is able to increase skin thickness [1]. Exercise and skin – an overlooked connection Skin is the largest organ of the

Senolytics Restore Regeneration in Killifish

Researchers publishing in npj regenerative medicine have found that destroying senescent cells through a well-known senolytic combination gives older killifish back some of their regenerative abilities. Regeneration, for a while Killifish, like starfish and salamanders, are some of the most well-known regenerators of the animal kingdom,

Elderly walking

Better Health in Older Adults, One Step at a Time

Research published in Experimental Gerontology suggests that even smaller amounts of daily physical activity can benefit people over 60 [1]. Cardiometabolic health and physical activity The positive influence of exercise on health is widely known. However, the recommended 150 minutes per week of moderate-to-vigorous exercise can

The Journal Club is a monthly livestream hosted by Dr. Oliver Medvedik which covers the latest aging research papers.

Journal Club July 2023 – Zoom Details Within

The Journal Club returns on 25th July at 12:00 Eastern time to the Lifespan.io Facebook channel. Editing mitochondrial DNA (mtDNA) has long been a challenge, and systems such as CRISPR, which make editing regular DNA faster and easier, are very difficult to use when it comes

The Journal Club is a monthly livestream hosted by Dr. Oliver Medvedik which covers the latest aging research papers.

Editing Mitochondrial DNA

The Journal Club returns on 25th July at 12:00 Eastern time to the Lifespan.io Facebook channel. Editing mitochondrial DNA (mtDNA) has long been a challenge and systems such as CRISPR, which make editing regular DNA faster and easier, are very difficult to use when it comes

Fedichev Interview

Peter Fedichev Explains His Theory of Aging

Peter Fedichev, co-founder and CEO of Gero, is a relative newcomer to the field of geroscience with a background in physics and not in biology. However, Peter has firmly established himself and Gero in the longevity landscape by twice publishing in Nature, entering a lucrative collaboration

Disagreeing clocks

Using Proteins and RNA to Determine How Old You Are

A paper published in Aging goes into detail about the proteins and RNA pieces that increase and decrease with aging, suggesting a multiple-clock approach to biomarkers. Blood proteins change with age The researchers start out by discussing existing clocks based on such measurements as imaging [1]

Rhesus macaques

The Longevity Factor Klotho Improves Memory in Monkeys

Researchers have explained in Nature Aging how klotho, a factor associated with longevity, improves the cognitive abilities of rhesus macaques. Moving on from mice This paper begins with a discussion of klotho and how it relates to aging. In mice, klotho has been found to improve

Cnidarian

Cellular Senescence Drives Regeneration in Cnidarians

Scientists have demonstrated that full-body regeneration in cnidarians, a group of animals that includes the jellyfish and hydra, can be driven by signals from senescent cells [1]. This might be the original purpose of cellular senescence. Why can’t we regrow our arms? There are many examples

Creatine

Creatine on the Brain: A Review

A review recently published in Sports Medicine has discussed a considerable number of research papers that describe the effects of the muscle-building supplement creatine on the brain. Broadening the studies of a well-known supplement Creatine is a natural compound that is naturally formed in the human