Lifespan Research Institute

Category: News

Elderly intestines

Young Microbiomes in Very Old People

Research published today in Nature Aging has illustrated how the gut microbiomes of the longest-lived people are more likely to have bacterial populations associated with youth. A known difference This

Bryan Johnson Face

Bryan Johnson And His Race Against Time

Bryan Johnson is an enigma in the longevity space, someone who is difficult to place in a familiar category or determine the net impact of. Johnson is a successful tech

Rejuvenation Roundup March

Rejuvenation Roundup March 2023

March marks the beginning of spring and the time for renewal, and this month, labs around the world have looked into renewing older concepts of aging and discovered potential methods

Elderly eye

Using AI to Measure Age Through the Eyes

An accepted manuscript in eLife Sciences has described eyeAge, a new clock that uses deep learning to analyze the eye in detail in order to predict chronological age and age acceleration.

Abstract DNA

Inhibiting DREAM for Enhanced DNA Damage Repair

In a new study published in Nature Structural and Molecular Biology, researchers have demonstrated that by manipulating the DREAM protein complex, a major regulator of DNA damage response, it might

Baton passing

Vesicles from Senescent Cells Encourage Young Stem Cells

Scientists have shown that extracellular vesicles derived from senescent stem cells can improve the proliferation, viability, and migration capacity of healthy stem cells [1]. Cell-to-cell packages Extracellular vesicles (EVs, not

Elderly smiling

Senescent Cells and Loose Teeth

A team of researchers has recently published a study on the effects of senescence on periodontal tissues in Aging. Connecting bones and teeth We have previously outlined a study showing

Age Later

Dr. Nir Barzilai on How to Age Later

In “Age Later: Healthspan, Lifespan, and the New Science of Longevity,” Dr. Nir Barzilai provides an insightful and comprehensive overview of the latest research on aging and longevity. As a

Running seniors

Long-Term Resistance Exercise Increases Autophagy

In a new systemic review published in Autophagy Reports, researchers have demonstrated that exercise plays a role in regulating autophagy, depending on its type [1]. Manipulating autophagy  Disabled autophagy was

Elderly intestines

Young Microbiomes in Very Old People

Research published today in Nature Aging has illustrated how the gut microbiomes of the longest-lived people are more likely to have bacterial populations associated with youth. A known difference This is far from the first study showing a connection between a healthy, youthful microbiome and enhanced

Editorial

We Continue To Engage Growing Audiences About Rejuvenation

For those of us in the Northern Hemisphere, spring has finally arrived, and with it, we have lots of news to share with you! Happy birthday to us! That’s right, folks, it’s our birthday, and we are celebrating nine years of being a non-profit organization that

Bryan Johnson Face

Bryan Johnson And His Race Against Time

Bryan Johnson is an enigma in the longevity space, someone who is difficult to place in a familiar category or determine the net impact of. Johnson is a successful tech entrepreneur of humble origins who sold his company Braintree Venmo to PayPal in 2013 for 800

Swimming in ice

Cold Temperatures Stimulate Lifespan-Associated Protein

A paper published today in Nature Aging describes how cold temperatures stimulate the production of PA28γ, a protein that appears to increase lifespan in worms and cells. An explanation for a commonly held belief Cold temperatures have been associated with longevity for more than a hundred

Rejuvenation Roundup March

Rejuvenation Roundup March 2023

March marks the beginning of spring and the time for renewal, and this month, labs around the world have looked into renewing older concepts of aging and discovered potential methods for renewing our bodies. LEAF News Partnership Opportunities for the 5th Annual Age-Related Disease Therapeutics Summit:

Walking is important but has diminishing returns for mortality risk.

Daily Step Count, Less Mortality, Diminishing Returns

A new study using wearable accelerometers suggests that you don’t have to clock extreme numbers of steps every day to stay healthy [1]. Do you always need to hit the target? A tight association between physical activity and health is widely known [2]. In fact, staying

Elderly eye

Using AI to Measure Age Through the Eyes

An accepted manuscript in eLife Sciences has described eyeAge, a new clock that uses deep learning to analyze the eye in detail in order to predict chronological age and age acceleration. Retinal signs of aging This project was developed with the knowledge that fundus imagery, which shows

Abstract DNA

Inhibiting DREAM for Enhanced DNA Damage Repair

In a new study published in Nature Structural and Molecular Biology, researchers have demonstrated that by manipulating the DREAM protein complex, a major regulator of DNA damage response, it might be possible to alter the number of DNA mutations accumulated with age [1]. Mutations and DREAMs

Baton passing

Vesicles from Senescent Cells Encourage Young Stem Cells

Scientists have shown that extracellular vesicles derived from senescent stem cells can improve the proliferation, viability, and migration capacity of healthy stem cells [1]. Cell-to-cell packages Extracellular vesicles (EVs, not to be confused with electric vehicles) are tiny membrane-bound bubbles that are emitted by cells and

Elderly smiling

Senescent Cells and Loose Teeth

A team of researchers has recently published a study on the effects of senescence on periodontal tissues in Aging. Connecting bones and teeth We have previously outlined a study showing a relationship between gum disease and biomarkers of inflammation. Noting that aging itself is a risk

Age Later

Dr. Nir Barzilai on How to Age Later

In “Age Later: Healthspan, Lifespan, and the New Science of Longevity,” Dr. Nir Barzilai provides an insightful and comprehensive overview of the latest research on aging and longevity. As a renowned gerontologist and the director of the Institute for Aging Research at the Albert Einstein College

Zehnder Interview

Ashley Zehnder on Harnessing Animal Genes Against Aging

Many species have developed amazing mechanisms to cope with various drivers of aging. We have previously interviewed two prominent experts that study those evolutionary marvels: Steven Austad and Emma Teeling. However, this research is not purely academic anymore. A handful of bold entrepreneurs are trying to

Muscle factor

Promoting Muscle Regeneration With an Immune Factor

A paper published today in Nature Aging has shown that a macrophage-regulating factor has a significant impact on muscle regeneration. Healing slows with aging The researchers note two key reasons for the decline of regenerative abilities with aging. The first is stem cell exhaustion, the gradual

The Journal Club is a monthly livestream hosted by Dr. Oliver Medvedik which covers the latest aging research papers.

Journal Club March 2023 + Zoom Connection Details

The Journal Club returns on Tuesday 28th March at 12:00 PM Eastern time to the Lifespan.io Facebook channel. This month Dr. Oliver Medvedik will be exploring a recent study which looked at the effects of prolonged fasting on human macrophages and how metabolites from that fasting

Running seniors

Long-Term Resistance Exercise Increases Autophagy

In a new systemic review published in Autophagy Reports, researchers have demonstrated that exercise plays a role in regulating autophagy, depending on its type [1]. Manipulating autophagy  Disabled autophagy was recently acknowledged as a hallmark of aging. Indeed, boosting the ability of cells to get rid