Category: News
Mediterranean Diet Might Lower Risk of Dementia
March 21, 2023
In a large-scale observational study, British scientists have shown that high levels of adherence to the Mediterranean diet might substantially lower the risk of dementia [1]. A healthy diet The
Vital Muscle Enzyme Declines With Aging
March 20, 2023
Research published in Nature Metabolism has described PCYT2, an enzyme essential for muscle function, and how it declines with aging. A necessary lipid synthesizer in muscle Human beings need PCYT2
The Human Cost of Metabolic Diseases
March 17, 2023
A new paper published in Cell Metabolism has shown the growing influence of metabolic diseases in an aging population. Related diseases studied together Metabolic diseases include hypertension, type 2 diabetes,
Rep. Bilirakis on the Longevity Science Caucus
March 17, 2023
We in the longevity field have received powerful allies on Capitol Hill with the creation of the bipartisan Congressional Caucus for Longevity Science. We had the opportunity to ask questions
Sleep Apnea and Inflammatory Biomarkers of Tooth Decay
March 16, 2023
A study published in Heliyon has explained a relationship between sleep apnea and an increase of inflammatory factors in the mouth that are connected to the gum disease peridontitis. Connected
Inflammation Strongly Predicts Mortality After Statin Use
March 16, 2023
Analyzing data from three clinical trials, scientists have shown that excessive inflammation is a much stronger predictor of cardiovascular and all-cause mortality in patients on statins than excessive LDL cholesterol
Excessive Fat, Not Sugar, Leads to Obesity in Mice
March 15, 2023
In a new study published in Endocrinology and Metabolism, researchers have shown that fat rather than sugar is the macronutrient that drives obesity and other detrimental metabolic changes if it
Epigenetic Biomarker for Measuring Aging Through Fitness
March 15, 2023
A new biomarker for measuring biological aging based on physical fitness has been published in Aging, and it has been found to be useful in predicting health issues. A clock
Prof. George Church on Cellular Reprogramming and Longevity
March 14, 2023
Professor of Genetics at Harvard Medical School, a veteran geroscientist, and a serial entrepreneur, George Church hardly needs an introduction. While we are always happy to discuss the present and
Mitochondria, DNA, and Oxidative Stress
March 13, 2023
A paper published in Experimental Gerontology has provided a fresh and detailed look at the effects of oxidative stress on longevity. Revisiting an old theory The free radical theory of
New Treatment Alleviates Depression Symptoms in Mice
March 10, 2023
Scientists have shown that the protein GDF11 can reverse depression-like symptoms in naturally aged mice and in a mouse model of depression. Depressed humans have lower GDF11 as well [1].
Young Blood Alters Gene Expression in Old Brain Cells
March 9, 2023
Research published today in Nature Aging has shown that heterochronic parabiosis, the circulatory joining of young and old organisms, has rejuvenative effects on the gene expression of multiple types of
Metformin and Rapamycin Rejuvenate Stem Cells in Mice
March 8, 2023
In a new study published in Aging Cell, researchers have shown that two promising anti-aging agents, the antibiotic rapamycin and the anti-diabetic drug metformin, reverse aging in a population of
New Small Molecule Alleviates Alzheimer’s in Mouse Model
March 7, 2023
Scientists have developed a custom-made molecule that targets a post-translationally modified kinase linked to Alzheimer’s, improving symptoms in a murine model of the disease [1]. A novel approach to neutralizing
Extracellular Vesicles as a Hallmark of Aging
March 6, 2023
A review paper published in Cells has described multiple ways in which the secretion of extracellular vesicles (EVs) changes with aging, leading the authors to propose it as its own
Mediterranean Diet Might Lower Risk of Dementia
March 21, 2023
In a large-scale observational study, British scientists have shown that high levels of adherence to the Mediterranean diet might substantially lower the risk of dementia [1]. A healthy diet The Mediterranean diet, which is based on ingredients such as olive oil, vegetables, legumes, fish, and whole
Vital Muscle Enzyme Declines With Aging
March 20, 2023
Research published in Nature Metabolism has described PCYT2, an enzyme essential for muscle function, and how it declines with aging. A necessary lipid synthesizer in muscle Human beings need PCYT2 as part of the Kennedy pathway to synthesize two critical components of the phosopholipid membrane that
The Human Cost of Metabolic Diseases
March 17, 2023
A new paper published in Cell Metabolism has shown the growing influence of metabolic diseases in an aging population. Related diseases studied together Metabolic diseases include hypertension, type 2 diabetes, hyperlipidemia, obesity, and non-alcoholic fatty liver disease [1]. These diseases, representing fundamental problems with how the
Rep. Bilirakis on the Longevity Science Caucus
March 17, 2023
We in the longevity field have received powerful allies on Capitol Hill with the creation of the bipartisan Congressional Caucus for Longevity Science. We had the opportunity to ask questions of one of its co-chairs. Longevity is bipartisan The fight against aging must become one of
Sleep Apnea and Inflammatory Biomarkers of Tooth Decay
March 16, 2023
A study published in Heliyon has explained a relationship between sleep apnea and an increase of inflammatory factors in the mouth that are connected to the gum disease peridontitis. Connected dangers This paper begins with a discussion of peridontitis, which is caused by infection with anaerobic
Inflammation Strongly Predicts Mortality After Statin Use
March 16, 2023
Analyzing data from three clinical trials, scientists have shown that excessive inflammation is a much stronger predictor of cardiovascular and all-cause mortality in patients on statins than excessive LDL cholesterol levels. These findings can upend the current standard of care for such patients [1]. The two
Excessive Fat, Not Sugar, Leads to Obesity in Mice
March 15, 2023
In a new study published in Endocrinology and Metabolism, researchers have shown that fat rather than sugar is the macronutrient that drives obesity and other detrimental metabolic changes if it constitutes a large proportion of dietary calories [1]. Obesity, diet, and the microbiome Obesity is associated
Epigenetic Biomarker for Measuring Aging Through Fitness
March 15, 2023
A new biomarker for measuring biological aging based on physical fitness has been published in Aging, and it has been found to be useful in predicting health issues. A clock with a different purpose Epigenetic clocks are most notable for their direct relationship to biological age,
Prof. George Church on Cellular Reprogramming and Longevity
March 14, 2023
Professor of Genetics at Harvard Medical School, a veteran geroscientist, and a serial entrepreneur, George Church hardly needs an introduction. While we are always happy to discuss the present and future of geroscience with him, this interview focuses on the two gene therapy papers that he
Mitochondria, DNA, and Oxidative Stress
March 13, 2023
A paper published in Experimental Gerontology has provided a fresh and detailed look at the effects of oxidative stress on longevity. Revisiting an old theory The free radical theory of aging, which purports that reactive oxygen species (ROS) are the core driver of aging, was developed
New Treatment Alleviates Depression Symptoms in Mice
March 10, 2023
Scientists have shown that the protein GDF11 can reverse depression-like symptoms in naturally aged mice and in a mouse model of depression. Depressed humans have lower GDF11 as well [1]. Depression and aging Severe mental disorders, including depression, have been linked to significantly shorter lifespans [2].
Young Blood Alters Gene Expression in Old Brain Cells
March 9, 2023
Research published today in Nature Aging has shown that heterochronic parabiosis, the circulatory joining of young and old organisms, has rejuvenative effects on the gene expression of multiple types of brain cells in mice. Parabiosis affects a wide variety of factors at once Heterochronic parabiosis is
Metformin and Rapamycin Rejuvenate Stem Cells in Mice
March 8, 2023
In a new study published in Aging Cell, researchers have shown that two promising anti-aging agents, the antibiotic rapamycin and the anti-diabetic drug metformin, reverse aging in a population of intestinal stem cells [1]. The aging intestine Older people are more prone to gastrointestinal problems [2].
New Small Molecule Alleviates Alzheimer’s in Mouse Model
March 7, 2023
Scientists have developed a custom-made molecule that targets a post-translationally modified kinase linked to Alzheimer’s, improving symptoms in a murine model of the disease [1]. A novel approach to neutralizing proteins MAPK is a family of kinases involved in numerous cellular processes. One member of this
Extracellular Vesicles as a Hallmark of Aging
March 6, 2023
A review paper published in Cells has described multiple ways in which the secretion of extracellular vesicles (EVs) changes with aging, leading the authors to propose it as its own hallmark. Extracellular vesicles and their uses This review begins with an outline and explanation of extracellular