Lifespan Research Institute

Category: News

The Journal Club is a monthly livestream hosted by Dr. Oliver Medvedik which covers the latest aging research papers.

Journal Club February 2023

The Journal Club, hosted by Dr. Oliver Medvedik, returns to the Lifespan.io Facebook page at 12:00 on Tuesday, February 28th. This month, we are covering a recent paper that showed

Sinclair Why We Age

Reviewing David Sinclair’s First Lifespan Book

David Sinclair, PhD, esteemed molecular geneticist at Harvard, believes that aging is a disease that should be attacked at its roots. Furthermore, he believes if we are to make efficient

Brain construction

Human Organoids for Brain Regeneration

Researchers publishing in Cell Stem Cell have used organoids derived from human cells to regrow the brain tissue of rats. The need to repair permanent damage While human beings do

Pink Hourglass

Young Ovarian Tissue Rejuvenates Old Mice

In a paper published in Frontiers in Endocrinology, researchers have shown that transplanted young ovarian tissue improves the immune function of old recipient mice even if they are hormone-depleted [1].

Pure lithium

Lithium Is Linked to Lower Mortality

In an epidemiological study published in Aging, scientists have shown that patients who take lithium have much lower all-cause mortality than patients on other psychotropic drugs [1]. Is lithium a

Enlarged heart

The Link Between NAD+ and Heart Failure

A paper published today in Nature Cardiovascular Research has explained a relationship between dilated cardiac myopathy (DCM), epigenetic dysregulation, NAD+, and the epigenetic regulatory molecule Kdm8. A gradual decline of

Tendon inflammation

Extracellular Vesicles for Tendon Healing

Researchers publishing in Journal of Nanobiotechnology have found that extracellular vesicles derived from young cells are effective in treating a model of a common tendon disease. Tendinopathy and stem cells

Brain virus

Viral Exposure Might Increase the Risk of Neurodegeneration

In a paper published in Neuron, researchers have shown an association between exposure to various viruses and an increased risk of several neurodegenerative diseases, including Alzheimer’s and Parkinson’s diseases [1].

Near IR

Diagnosing Alzheimer’s in the Near Infrared

In Nature Biomedical Engineering, a team of researchers has published an innovative method of making tau tangles and amyloid beta visible in the near infrared, allowing doctors and researchers to

Stitched apple

Is Increasing Human Lifespan Unnatural?

Whenever the topic of any possible increased healthy longevity through science is discussed, a common objection to developing the technology is that it is unnatural. This argument usually arises during

Midday Exercise Might Be Better In Preventing Mortality

Midday Exercise Might Be Better In Preventing Mortality

Scientists have found that the time of day when you exercise might be an important factor in lowering all-cause and cardiovascular mortality [1]. Exercise is good, but what about timing? The value of physical activity for health and longevity is unquestionable [2], even if some doubts

The Journal Club is a monthly livestream hosted by Dr. Oliver Medvedik which covers the latest aging research papers.

Journal Club February 2023

The Journal Club, hosted by Dr. Oliver Medvedik, returns to the Lifespan.io Facebook page at 12:00 on Tuesday, February 28th. This month, we are covering a recent paper that showed a method of restoring youthful collagen production in aged skin [1]. If you would like some

Sinclair Why We Age

Reviewing David Sinclair’s First Lifespan Book

David Sinclair, PhD, esteemed molecular geneticist at Harvard, believes that aging is a disease that should be attacked at its roots. Furthermore, he believes if we are to make efficient and sensible use our medical resources, we must move away from the “whack-a-mole” approach to treating

Lumbar spine

High Cholesterol Associated With Lower Bone Mineral Density

A team of researchers has described an association between reduced bone density in the lumbar spine and high total cholesterol in a paper published in Aging. Previous studies were conflicting In various populations, conflicting evidence has been found regarding a relationship between cholesterol and bone density.

Arm muscle

Nicotinamide Riboside Improves Muscle Energy in Trial

Scientists have shown that long-term treatment with a popular NAD+ precursor can raise NAD+ levels in blood and muscle and increase mitochondria content and function [1]. Twin-based design NAD+ is an important coenzyme that performs multiple functions, including mitochondrial energy production. NAD+ levels decrease with aging,

Brain construction

Human Organoids for Brain Regeneration

Researchers publishing in Cell Stem Cell have used organoids derived from human cells to regrow the brain tissue of rats. The need to repair permanent damage While human beings do generate new neurons (neurogenesis) [1], this ability is very limited, in both region and amount. Brain

Pink Hourglass

Young Ovarian Tissue Rejuvenates Old Mice

In a paper published in Frontiers in Endocrinology, researchers have shown that transplanted young ovarian tissue improves the immune function of old recipient mice even if they are hormone-depleted [1]. Not just a reproductive matter Although women generally live longer than men, women spend almost half

Pure lithium

Lithium Is Linked to Lower Mortality

In an epidemiological study published in Aging, scientists have shown that patients who take lithium have much lower all-cause mortality than patients on other psychotropic drugs [1]. Is lithium a longevity drug? Lithium has long been prescribed for certain psychiatric conditions, mainly bipolar disorder. With time,

Enlarged heart

The Link Between NAD+ and Heart Failure

A paper published today in Nature Cardiovascular Research has explained a relationship between dilated cardiac myopathy (DCM), epigenetic dysregulation, NAD+, and the epigenetic regulatory molecule Kdm8. A gradual decline of ability DCM occurs when the left ventricle of the heart becomes enlarged and loses its ability

Victory cup

Meet hack-age, Winners of the January 2023 LongHack

On January 22nd, hack-age won the 2023 LongHack competition, which carried a grand prize of 5,500 VITA and 3,500 USD. Lifespan.io caught up with the team behind the winning project to learn more about their idea and their experience competing in the hackathon. What is LongHack?

Tendon inflammation

Extracellular Vesicles for Tendon Healing

Researchers publishing in Journal of Nanobiotechnology have found that extracellular vesicles derived from young cells are effective in treating a model of a common tendon disease. Tendinopathy and stem cells Swelling, weakness, tenderness, and tendon pain during activities are the characteristic symptoms of chronic tendinopathy [1],

Brain virus

Viral Exposure Might Increase the Risk of Neurodegeneration

In a paper published in Neuron, researchers have shown an association between exposure to various viruses and an increased risk of several neurodegenerative diseases, including Alzheimer’s and Parkinson’s diseases [1]. Roots of neurodegeneration There are many causes underlying neurodegeneration, such as genetic predisposition, toxin exposure, poor

Old DNA

Retroviruses Contribute to the Spread of Cellular Senescence

Scientists have found that the remnants of the ancient retrovirus family HERVK, which reside in our genome, are transcribed more frequently in aged cells. This is caused by cellular senescence and accelerates it, including in the neighboring cells, when those are infected by retroviral particles [1].

Near IR

Diagnosing Alzheimer’s in the Near Infrared

In Nature Biomedical Engineering, a team of researchers has published an innovative method of making tau tangles and amyloid beta visible in the near infrared, allowing doctors and researchers to see through bone with relatively simple equipment. Current methods are difficult There are three main approaches

Stitched apple

Is Increasing Human Lifespan Unnatural?

Whenever the topic of any possible increased healthy longevity through science is discussed, a common objection to developing the technology is that it is unnatural. This argument usually arises during discussions of therapies that directly address the various processes of aging, and it is important to understand their basis