Category: News
Senolytic Improves Metabolism in Mice
February 3, 2023
Scientists have shown that a popular senolytic combination of dasatinib and quercetin improves glucose tolerance and fasting blood glucose levels in aged mice [1]. The question of metabolism Cellular senescence
Photosensitive Drug Clears Senescent Cells
February 2, 2023
Research published in Nature Aging has shown that a photosensitive senolytic drug can be used to selectively remove senescent cells, slowing functional organ aging in mice. A problem of delivery
Ultrasound Rejuvenates Senescent Cells Through Autophagy
February 1, 2023
In a preprint paper, the researchers have shown that low-frequency ultrasound treatment decreases senescence and improves the physical performance of aged mice [1]. Mechanical approach Cellular senescence, the inability of
Rejuvenation Roundup January 2023
February 1, 2023
As 2023 continues, so does new research into rejuvenation, regeneration, and restoration. Let’s see what’s been done to reverse age-related diseases in January. Lifespan.io News Team and activities New Year,
VitaDAO Closes $4.1 Million Fundraising Round
January 31, 2023
VitaDAO, a decentralized organization funding early-stage longevity research and biotech start-ups, has announced the successful closing of a $4.1 million funding round dedicated to financing future longevity projects and furthering
Longevity-Associated Allele Protects Heart Function in Mice
January 31, 2023
Scientists have shown that a longevity-associated variant of the BPIFB4 gene protects cardiovascular health, including when introduced by viral vectors [1]. All you need is LAV Among age-related pathologies, cardiovascular
Gene Therapy for Heart Regeneration in Living Animals
January 30, 2023
Research published in Cell Stem Cell has described how previously unmodified animals have been given regenerative abilities akin to those of zebrafish, restoring their heart muscle after injury. A TREE
New Way to Help Aging Cells Produce Collagen
January 27, 2023
Scientists have demonstrated that extracellular vesicles loaded with mRNA coding for collagen production can be easily produced and delivered into aging fibroblasts in vitro and in vivo, boosting collagen levels
Brain Aging on a Small, Physical Level
January 26, 2023
A new publication in Nature Aging has explained a great deal about aging of the neurovascular system, showing where and how the brain’s blood supply changes with aging in a
Eric Verdin on the Buck, Nutrition, and Ketosis
January 26, 2023
Six years ago, Dr. Eric Verdin, already a highly acclaimed veteran geroscientist, was catapulted to the forefront of the field when he agreed to lead the Buck Institute for Research
New Year, Same Goal to End Age-Related Diseases
January 26, 2023
The new year is well underway, and we have been our usual busy selves. Join us for the first editorial of the year, and find out about the awesome things
Caloric Restriction Does Not Extend Lifespan in Every Model
January 25, 2023
In a preprint paper, researchers have evaluated the effect of caloric restriction on two long-lived planarian species in various environments that mimic the stochasticity of the real world [1]. Does
Partial Reprogramming Extends Lifespan in Old Mice
January 25, 2023
The journal club returns on Tuesday 31st January at 12:00 Eastern on our Facebook page with host Dr. Oliver Medvedik. We are looking at a preprint this time where partial
Journal Club January 2023
January 25, 2023
The journal club returns on Tuesday 31st January at 12:00 Eastern on our Facebook page with host Dr. Oliver Medvedik. We are looking at a preprint this time where partial
NMN Reduces Metastasis in Difficult Breast Cancer Model
January 24, 2023
In a new paper published in Nature, scientists have found that raising NAD+ levels via supplementation with nicotinamide mononucleotide (NMN) activates SIRT1 to dampen metastasis in mouse TNBC models [1].
Senolytic Improves Metabolism in Mice
February 3, 2023
Scientists have shown that a popular senolytic combination of dasatinib and quercetin improves glucose tolerance and fasting blood glucose levels in aged mice [1]. The question of metabolism Cellular senescence is one of the hallmarks of aging, and senolytics, drugs that clear away senescent cells, have
Photosensitive Drug Clears Senescent Cells
February 2, 2023
Research published in Nature Aging has shown that a photosensitive senolytic drug can be used to selectively remove senescent cells, slowing functional organ aging in mice. A problem of delivery The researchers name three problems with senolytic drugs: specificity to senescent cells (accuracy), controllability of administration
Ultrasound Rejuvenates Senescent Cells Through Autophagy
February 1, 2023
In a preprint paper, the researchers have shown that low-frequency ultrasound treatment decreases senescence and improves the physical performance of aged mice [1]. Mechanical approach Cellular senescence, the inability of aged cells to divide while still being metabolically active, is one of the hallmarks of aging.
Rejuvenation Roundup January 2023
February 1, 2023
As 2023 continues, so does new research into rejuvenation, regeneration, and restoration. Let’s see what’s been done to reverse age-related diseases in January. Lifespan.io News Team and activities New Year, Same Goal to End Age-Related Diseases: The new year is well underway, and we have been
VitaDAO Closes $4.1 Million Fundraising Round
January 31, 2023
VitaDAO, a decentralized organization funding early-stage longevity research and biotech start-ups, has announced the successful closing of a $4.1 million funding round dedicated to financing future longevity projects and furthering its commercialization and licensing strategy for IP-NFT assets. Key contributors to the fundraising round include Shine
Longevity-Associated Allele Protects Heart Function in Mice
January 31, 2023
Scientists have shown that a longevity-associated variant of the BPIFB4 gene protects cardiovascular health, including when introduced by viral vectors [1]. All you need is LAV Among age-related pathologies, cardiovascular disease is the most prolific killer, claiming about 700,000 victims every year in the US alone
Gene Therapy for Heart Regeneration in Living Animals
January 30, 2023
Research published in Cell Stem Cell has described how previously unmodified animals have been given regenerative abilities akin to those of zebrafish, restoring their heart muscle after injury. A TREE of life This study is introduced with a discussion of gene therapy as a field, noting
New Way to Help Aging Cells Produce Collagen
January 27, 2023
Scientists have demonstrated that extracellular vesicles loaded with mRNA coding for collagen production can be easily produced and delivered into aging fibroblasts in vitro and in vivo, boosting collagen levels and eliminating signs of skin aging in mice [1]. Superior delivery method Finding a good way
Brain Aging on a Small, Physical Level
January 26, 2023
A new publication in Nature Aging has explained a great deal about aging of the neurovascular system, showing where and how the brain’s blood supply changes with aging in a mouse model. A branching network of blood vessels In the neurovascular system, arteries lead to arterioles,
Eric Verdin on the Buck, Nutrition, and Ketosis
January 26, 2023
Six years ago, Dr. Eric Verdin, already a highly acclaimed veteran geroscientist, was catapulted to the forefront of the field when he agreed to lead the Buck Institute for Research on Aging (or simply “the Buck”), a renowned research institution based in Novato, CA. We talked
New Year, Same Goal to End Age-Related Diseases
January 26, 2023
The new year is well underway, and we have been our usual busy selves. Join us for the first editorial of the year, and find out about the awesome things we have been doing for longer, healthier lives. Decentralized science could support aging research progress Lifespan.io
Caloric Restriction Does Not Extend Lifespan in Every Model
January 25, 2023
In a preprint paper, researchers have evaluated the effect of caloric restriction on two long-lived planarian species in various environments that mimic the stochasticity of the real world [1]. Does the theory hold? According to a theory that is largely based on plentiful data from model
Partial Reprogramming Extends Lifespan in Old Mice
January 25, 2023
The journal club returns on Tuesday 31st January at 12:00 Eastern on our Facebook page with host Dr. Oliver Medvedik. We are looking at a preprint this time where partial reprogramming factors were used to reverse some aspects of aging in old mice. The paper is
Journal Club January 2023
January 25, 2023
The journal club returns on Tuesday 31st January at 12:00 Eastern on our Facebook page with host Dr. Oliver Medvedik. We are looking at a preprint this time where partial reprogramming factors were used to reverse some aspects of aging in old mice. The paper is
NMN Reduces Metastasis in Difficult Breast Cancer Model
January 24, 2023
In a new paper published in Nature, scientists have found that raising NAD+ levels via supplementation with nicotinamide mononucleotide (NMN) activates SIRT1 to dampen metastasis in mouse TNBC models [1]. A double-edged sword NAD+ is a ubiquitous co-enzyme that facilitates numerous processes in our body, from