Category: News
Extracellular Vesicles from Young Stem Cells Rejuvenate Mice
November 8, 2022
Scientists have shown that injection of extracellular vesicles secreted by young adipose-derived stem cells increases fitness and promotes tissue rejuvenation in aged mice [1]. Mode of communication Small extracellular vesicles
Gene Therapy to Delay Reproductive Senescence
November 7, 2022
A team of Spanish researchers publishing in Aging have reported that they can delay reproductive senescence in female rats by stimulating the production of insulin growth factor 1 (IGF-1) through
Lou Hawthorne, NaNotics on Cleaning Blood with Nanoparticles
November 4, 2022
Lou Hawthorne is the founder and CEO of NaNotics, a biotech company that creates nanoparticles that can soak up harmful molecules in circulation. This paradigm-shifting technology can be used to
Protecting Memory Through Gut Bacteria
November 3, 2022
Researchers publishing in Nutrients have shown that adding a strain of lactic acid bacteria to the gut flora of older, memory-impaired people partially alleviates their memory problems. A specific anti-inflammatory
Klotho Reduces Arterial Calcification Through Autophagy
November 2, 2022
In a new study published in Oxidative Medicine and Cellular Longevity, the researchers have shown that klotho ameliorates vascular calcification via increased autophagy [1]. ‘Rusty’ arteries Vascular calcification, the deposition
Cellular Reprogramming Extends Lifespan, Healthspan in Mice
November 1, 2022
Scientists have shown that continuous low-dose induction of reprogramming factors and a single early life reprogramming treatment both significantly increase lifespan and healthspan in progeroid mice while altering their
Rejuvenation Roundup October 2022
November 1, 2022
Ghouls, goblins, and ghosts were all on display last night, but today, we bring you something even scarier: Aging! Let’s see what’s been done to fight back against aging in
Vitamin D Combats Oxidative Stress in Gingival Cells
October 31, 2022
A cellular study published in the Journal of Dental Sciences has shown that Vitamin D alleviates inflammaging related to the oxidative stress brought on by advanced glycation end-products (AGEs). Diabetes
Turn.bio Announces Preliminary Results of a CAR-T Cell Study
October 28, 2022
Turn.bio has announced that its proprietary cellular reprogramming technology was able to significantly increase the proliferative and cytotoxic potential of premanufactured CAR-T cells in vitro. Turn.bio, a developer of mRNA-based
New Compounds Beat Resveratrol in Sirtuin Activation
October 27, 2022
A recent study published in Molecules has tested multiple thiazole-based derivatives that appear to activate the sirtuin SIRT1 more than resveratrol [1]. Sirtuins Resveratrol, commonly found in grape skins and
Olive Oil Linked to Significantly Lower Mortality
October 27, 2022
In a new study published in the journal Nutritional Epidemiology, scientists have found a strong association between olive oil consumption and lower risk of cardiovascular, cancer, and all-cause mortality [1].
Pain Is Associated with Increased Risk of Falls in Adults
October 26, 2022
In a new longitudinal study published in European Geriatric Medicine, the researchers have shown that people experiencing moderate to severe pain in multiple sites have an increased risk of falls,
Intermittent Exercise Encourages Muscle Protein Uptake
October 24, 2022
A research paper published in the Journal of Applied Physiology has found that regular, intermittent exercise encourages amino acids to form proteins in muscle. Anabolic resistance Previous research has found
HIIT and Intermittent Fasting Show Cumulative Effect
October 21, 2022
Scientists have shown that both high-intensity interval training (HIIT) and time-restricted eating improve metabolism in healthy overweight women, with their combination providing the biggest effect [1]. Which one is better?
Bowhead Whale’s Longevity May Be Due to Twin Genes
October 20, 2022
A preprint published in bioRxiv has partially explained the lifespan of the bowhead whale through its duplication of CDKN2C, which regulates how cells divide. Peto’s paradox It would be logical
Extracellular Vesicles from Young Stem Cells Rejuvenate Mice
November 8, 2022
Scientists have shown that injection of extracellular vesicles secreted by young adipose-derived stem cells increases fitness and promotes tissue rejuvenation in aged mice [1]. Mode of communication Small extracellular vesicles are one of the ways in which cells communicate with each other [2]. Basically, cells engulf
Gene Therapy to Delay Reproductive Senescence
November 7, 2022
A team of Spanish researchers publishing in Aging have reported that they can delay reproductive senescence in female rats by stimulating the production of insulin growth factor 1 (IGF-1) through gene therapy. A well-studied approach IGF-1 is a well-known anti-inflammatory compound, having shown positive effects in
Lou Hawthorne, NaNotics on Cleaning Blood with Nanoparticles
November 4, 2022
Lou Hawthorne is the founder and CEO of NaNotics, a biotech company that creates nanoparticles that can soak up harmful molecules in circulation. This paradigm-shifting technology can be used to fight cancer as well as various inflammatory disorders, such as sepsis, which kills more people than
Protecting Memory Through Gut Bacteria
November 3, 2022
Researchers publishing in Nutrients have shown that adding a strain of lactic acid bacteria to the gut flora of older, memory-impaired people partially alleviates their memory problems. A specific anti-inflammatory bacterium The researchers begin their paper by noting that mild cognitive impairment (MCI) is associated with
Klotho Reduces Arterial Calcification Through Autophagy
November 2, 2022
In a new study published in Oxidative Medicine and Cellular Longevity, the researchers have shown that klotho ameliorates vascular calcification via increased autophagy [1]. ‘Rusty’ arteries Vascular calcification, the deposition of minerals in the cardiovascular system, is a complex pathological process that accompanies aging. It is
Cellular Reprogramming Extends Lifespan, Healthspan in Mice
November 1, 2022
Scientists have shown that continuous low-dose induction of reprogramming factors and a single early life reprogramming treatment both significantly increase lifespan and healthspan in progeroid mice while altering their epigenetic landscape [1]. In vivo reprogramming Cellular reprogramming is the process of treating cells with compounds
Rejuvenation Roundup October 2022
November 1, 2022
Ghouls, goblins, and ghosts were all on display last night, but today, we bring you something even scarier: Aging! Let’s see what’s been done to fight back against aging in October. LEAF News Team and activities Leading the Movement for Longer and Healthier Lives: As a
Vitamin D Combats Oxidative Stress in Gingival Cells
October 31, 2022
A cellular study published in the Journal of Dental Sciences has shown that Vitamin D alleviates inflammaging related to the oxidative stress brought on by advanced glycation end-products (AGEs). Diabetes and AGEs Previous research has shown that the uncontrolled blood sugars associated with Type 2 diabetes
Turn.bio Announces Preliminary Results of a CAR-T Cell Study
October 28, 2022
Turn.bio has announced that its proprietary cellular reprogramming technology was able to significantly increase the proliferative and cytotoxic potential of premanufactured CAR-T cells in vitro. Turn.bio, a developer of mRNA-based cellular reprogramming technologies, has announced preliminary results from its current trial. The announcement was made by
New Compounds Beat Resveratrol in Sirtuin Activation
October 27, 2022
A recent study published in Molecules has tested multiple thiazole-based derivatives that appear to activate the sirtuin SIRT1 more than resveratrol [1]. Sirtuins Resveratrol, commonly found in grape skins and red wine, generated some of the initial interest in sirtuin activators after initial studies showing many
Olive Oil Linked to Significantly Lower Mortality
October 27, 2022
In a new study published in the journal Nutritional Epidemiology, scientists have found a strong association between olive oil consumption and lower risk of cardiovascular, cancer, and all-cause mortality [1]. Does olive oil prolong life? Olive oil being healthier than most other oils and fats is
Pain Is Associated with Increased Risk of Falls in Adults
October 26, 2022
In a new longitudinal study published in European Geriatric Medicine, the researchers have shown that people experiencing moderate to severe pain in multiple sites have an increased risk of falls, particularly in middle age [1]. Aging and falls In one’s youth, falling doesn’t seem dangerous and
Intermittent Exercise Encourages Muscle Protein Uptake
October 24, 2022
A research paper published in the Journal of Applied Physiology has found that regular, intermittent exercise encourages amino acids to form proteins in muscle. Anabolic resistance Previous research has found that a lack of activity accelerates the age-related muscle loss known as sarcopenia [1]. This has
HIIT and Intermittent Fasting Show Cumulative Effect
October 21, 2022
Scientists have shown that both high-intensity interval training (HIIT) and time-restricted eating improve metabolism in healthy overweight women, with their combination providing the biggest effect [1]. Which one is better? Good dietary habits and physical activity are currently our best options for living longer and healthier
Bowhead Whale’s Longevity May Be Due to Twin Genes
October 20, 2022
A preprint published in bioRxiv has partially explained the lifespan of the bowhead whale through its duplication of CDKN2C, which regulates how cells divide. Peto’s paradox It would be logical for longer-lived animals to be more susceptible to cancer than shorter-lived animals over time, as they