Lifespan Research Institute

Category: News

Walking Seniors

Astaxanthin Improves Endurance in Older Adults

In a new study published in International Journal of Environmental Research and Public Health, Japanese researchers have shown that astaxanthin supplementation improves endurance in healthy older adults [1]. Muscles succumb

Rats

Gene Therapy to Delay Reproductive Senescence

A team of Spanish researchers publishing in Aging have reported that they can delay reproductive senescence in female rats by stimulating the production of insulin growth factor 1 (IGF-1) through

Elderly Japanese couple

Protecting Memory Through Gut Bacteria

Researchers publishing in Nutrients have shown that adding a strain of lactic acid bacteria to the gut flora of older, memory-impaired people partially alleviates their memory problems. A specific anti-inflammatory

Clogged pipes

Klotho Reduces Arterial Calcification Through Autophagy

In a new study published in Oxidative Medicine and Cellular Longevity, the researchers have shown that klotho ameliorates vascular calcification via increased autophagy [1]. ‘Rusty’ arteries Vascular calcification, the deposition

Rejuvenation Roundup October

Rejuvenation Roundup October 2022

Ghouls, goblins, and ghosts were all on display last night, but today, we bring you something even scarier: Aging! Let’s see what’s been done to fight back against aging in

Healthy gums

Vitamin D Combats Oxidative Stress in Gingival Cells

A cellular study published in the Journal of Dental Sciences has shown that Vitamin D alleviates inflammaging related to the oxidative stress brought on by advanced glycation end-products (AGEs). Diabetes

Improvement

New Compounds Beat Resveratrol in Sirtuin Activation

A recent study published in Molecules has tested multiple thiazole-based derivatives that appear to activate the sirtuin SIRT1 more than resveratrol [1]. Sirtuins Resveratrol, commonly found in grape skins and

Olive oil

Olive Oil Linked to Significantly Lower Mortality

In a new study published in the journal Nutritional Epidemiology, scientists have found a strong association between olive oil consumption and lower risk of cardiovascular, cancer, and all-cause mortality [1].

Walking Seniors

Astaxanthin Improves Endurance in Older Adults

In a new study published in International Journal of Environmental Research and Public Health, Japanese researchers have shown that astaxanthin supplementation improves endurance in healthy older adults [1]. Muscles succumb to oxidative stress Aging leads to reduced muscle strength and endurance. Currently, exercising is the only

Kaeberlein

Dr. Matt Kaeberlein on WormBot and the Dog Aging Project

Dr. Matt Kaeberlein is a heavy hitter in the longevity field. While his name has become associated with the Dog Aging Project that he started a few years ago, his research interests span much wider. Besides an update on the Dog Aging Project, which is still

Basic mouse

Extracellular Vesicles from Young Stem Cells Rejuvenate Mice

Scientists have shown that injection of extracellular vesicles secreted by young adipose-derived stem cells increases fitness and promotes tissue rejuvenation in aged mice [1]. Mode of communication Small extracellular vesicles are one of the ways in which cells communicate with each other [2]. Basically, cells engulf

Rats

Gene Therapy to Delay Reproductive Senescence

A team of Spanish researchers publishing in Aging have reported that they can delay reproductive senescence in female rats by stimulating the production of insulin growth factor 1 (IGF-1) through gene therapy. A well-studied approach IGF-1 is a well-known anti-inflammatory compound, having shown positive effects in

Lou Hawthorne

Lou Hawthorne, NaNotics on Cleaning Blood with Nanoparticles

Lou Hawthorne is the founder and CEO of NaNotics, a biotech company that creates nanoparticles that can soak up harmful molecules in circulation. This paradigm-shifting technology can be used to fight cancer as well as various inflammatory disorders, such as sepsis, which kills more people than

Elderly Japanese couple

Protecting Memory Through Gut Bacteria

Researchers publishing in Nutrients have shown that adding a strain of lactic acid bacteria to the gut flora of older, memory-impaired people partially alleviates their memory problems. A specific anti-inflammatory bacterium The researchers begin their paper by noting that mild cognitive impairment (MCI) is associated with

Clogged pipes

Klotho Reduces Arterial Calcification Through Autophagy

In a new study published in Oxidative Medicine and Cellular Longevity, the researchers have shown that klotho ameliorates vascular calcification via increased autophagy [1]. ‘Rusty’ arteries Vascular calcification, the deposition of minerals in the cardiovascular system, is a complex pathological process that accompanies aging. It is

Playing mice 800x450

Cellular Reprogramming Extends Lifespan, Healthspan in Mice

  Scientists have shown that continuous low-dose induction of reprogramming factors and a single early life reprogramming treatment both significantly increase lifespan and healthspan in progeroid mice while altering their epigenetic landscape [1]. In vivo reprogramming Cellular reprogramming is the process of treating cells with compounds

Rejuvenation Roundup October

Rejuvenation Roundup October 2022

Ghouls, goblins, and ghosts were all on display last night, but today, we bring you something even scarier: Aging! Let’s see what’s been done to fight back against aging in October. LEAF News Team and activities Leading the Movement for Longer and Healthier Lives: As a

Healthy gums

Vitamin D Combats Oxidative Stress in Gingival Cells

A cellular study published in the Journal of Dental Sciences has shown that Vitamin D alleviates inflammaging related to the oxidative stress brought on by advanced glycation end-products (AGEs). Diabetes and AGEs Previous research has shown that the uncontrolled blood sugars associated with Type 2 diabetes

Computer cell

Turn.bio Announces Preliminary Results of a CAR-T Cell Study

Turn.bio has announced that its proprietary cellular reprogramming technology was able to significantly increase the proliferative and cytotoxic potential of premanufactured CAR-T cells in vitro. Turn.bio, a developer of mRNA-based cellular reprogramming technologies, has announced preliminary results from its current trial. The announcement was made by

Improvement

New Compounds Beat Resveratrol in Sirtuin Activation

A recent study published in Molecules has tested multiple thiazole-based derivatives that appear to activate the sirtuin SIRT1 more than resveratrol [1]. Sirtuins Resveratrol, commonly found in grape skins and red wine, generated some of the initial interest in sirtuin activators after initial studies showing many

Olive oil

Olive Oil Linked to Significantly Lower Mortality

In a new study published in the journal Nutritional Epidemiology, scientists have found a strong association between olive oil consumption and lower risk of cardiovascular, cancer, and all-cause mortality [1]. Does olive oil prolong life? Olive oil being healthier than most other oils and fats is

Elderly falls

Pain Is Associated with Increased Risk of Falls in Adults

In a new longitudinal study published in European Geriatric Medicine, the researchers have shown that people experiencing moderate to severe pain in multiple sites have an increased risk of falls, particularly in middle age [1]. Aging and falls In one’s youth, falling doesn’t seem dangerous and

Squatting at desk

Intermittent Exercise Encourages Muscle Protein Uptake

A research paper published in the Journal of Applied Physiology has found that regular, intermittent exercise encourages amino acids to form proteins in muscle. Anabolic resistance Previous research has found that a lack of activity accelerates the age-related muscle loss known as sarcopenia [1]. This has