Lifespan Research Institute

Category: News

LSN Longevity Prize

Announcing the Longevity Prize

The Longevity Prize is a series of prizes designed to honor the researchers who are helping to build a future in which age-related diseases are a thing of the past.

Skin aging

An In-Depth Review of Skin Aging Genes

In a new systematic review published in Scientific Reports, multiple genes driving skin aging were identified [1]. The authors start by explaining the intrinsic (genetic and chronological) and extrinsic (environmental)

Lewy bodies

Developing Nanobodies to Fight Parkinson’s Disease

A team of researchers publishing in Nature Communications has described nanobodies that can destroy the α-synuclein aggregates that characterize Lewy bodies, which are associated with dementia and Parkinson’s disease [1].

Mouse running

Ghrelin Is Associated with Worse Muscle Aging in Mice

A team of researchers publishing through Multidisciplinary Digital Publishing Institute has described an association between the peptide ghrelin and skeletal muscle aging in mice [1]. An appetite stimulant with potential

Rejuvenation Roundup July

Rejuvenation Roundup July 2022

Ending Age-Related Diseases 2022 will occur in less than two weeks, but that’s far from the only thing happening this month, and there’s plenty that happened last month as well.

Mebots

Mebots – Merging Gaming with Fitness

The pandemic has pushed many people indoors, and for many people, this has meant more time watching TV or using the computer. Screen time is now an average of 7

LSN Longevity Prize

Announcing the Longevity Prize

The Longevity Prize is a series of prizes designed to honor the researchers who are helping to build a future in which age-related diseases are a thing of the past. This new initiative aims to accelerate progress in the rejuvenation biotechnology field and encourage innovation. While

Blood vessels brain

Hypertension Is Associated with Brain Drainage Changes

Researchers publishing in Aging have found that enlarged perivascular spaces (ePVS) in the brain are correlated with vascular disorders [1]. These spaces, which are part of the brain’s glymphatic system, allow for the drainage of potentially dangerous metabolites such as beta amyloid [2]. A known biomarker

Skin aging

An In-Depth Review of Skin Aging Genes

In a new systematic review published in Scientific Reports, multiple genes driving skin aging were identified [1]. The authors start by explaining the intrinsic (genetic and chronological) and extrinsic (environmental) factors that drive skin aging. While the environmental factors that affect the rate of skin aging,

Back from the dead

Scientists Move the Boundaries of Post-Mortem Recovery

Researchers have been able to achieve substantial recovery of cellular and organismal activity in pigs that had been dead for a full hour [1]. When is it too late? Advances in resuscitation have already moved the boundaries of life and death, making it possible to revive

Lewy bodies

Developing Nanobodies to Fight Parkinson’s Disease

A team of researchers publishing in Nature Communications has described nanobodies that can destroy the α-synuclein aggregates that characterize Lewy bodies, which are associated with dementia and Parkinson’s disease [1]. What are nanobodies? Traditional antibody therapies, while promising in some studies, are too large to enter

Steve Horvath

Steve Horvath on the Present and Future of Epigenetic Clocks

Dr. Steve Horvath hardly needs an introduction, so we will be brief: he is the inventor of the epigenetic clock and, currently, principal investigator at Altos Labs. We talked about the recent developments in this immensely important field, including pan-mammalian clocks, two-species clocks, and single-cell clocks,

Sauna

Sauna Combined with Exercise Improves Cardiovascular Health

In a randomized, controlled trial, scientists have shown that sauna and exercise, when taken together, might have a synergistic, beneficial effect on cardiovascular health and cholesterol levels [1]. Turn up the heat Sauna bathing has been credited with many health benefits [2], predominantly for the cardiovascular

Mouse running

Ghrelin Is Associated with Worse Muscle Aging in Mice

A team of researchers publishing through Multidisciplinary Digital Publishing Institute has described an association between the peptide ghrelin and skeletal muscle aging in mice [1]. An appetite stimulant with potential side effects Ghrelin is a peptide containing 28 amino acids. Its main function is to stimulate

Periodontitis

VitaDAO Backs Research into Chronic Oral Disease

Periodontal disease affects more than 47% of adults aged 30 and over. For people over 65 years of age, that number rises to over 70%, making periodontitis one of the most commonly observed age-related illnesses. Jonathan An’s lab seeks to research inflammation-targeting compounds that can help

Small healthy meal

Caloric Restriction Improves Immune System Function

A new study published in Mechanisms of Aging and Development has shown that caloric restriction effectively restores T cell abundance in aged mice [1]. Is it really just about getting fewer calories? Caloric restriction has become a well-known anti-aging intervention, as it can reverse several hallmarks

Sophora Japonica

Hesperetin Upregulates Metabolism and Longevity in Mice

Researchers publishing in Journal of Biomedical Science have concluded that hesperetin, a compound found in various herbs, improves longevity in mice by promoting the expression of the pro-longevity gene Cisd2. Mitochondria and Cisd2 This paper begins with an explanation of mitochondrial dysfunction, one of the hallmarks

No results

Vitamin D Fails to Improve Bone Health in Mega-Study

A high-quality, randomized, controlled trial found no effect of vitamin D supplementation or blood levels on the incidence of fractures in an aging population [1]. The common perception doesn’t match the science It’s a long-held aphorism that vitamin D is good for bone health. This has

Rejuvenation Roundup July

Rejuvenation Roundup July 2022

Ending Age-Related Diseases 2022 will occur in less than two weeks, but that’s far from the only thing happening this month, and there’s plenty that happened last month as well. Here’s the latest rejuvenation news from July. LEAF News Health Benefits of Cocoa: Ryan O’Shea explains

Mebots

Mebots – Merging Gaming with Fitness

The pandemic has pushed many people indoors, and for many people, this has meant more time watching TV or using the computer. Screen time is now an average of 7 hours per day, which has led to all-time highs of obesity, worsening health, anxiety, and depression.

Future Clock

Epigenetic Age Acceleration Is Correlated with Mortality

In an important step for the longevity field, scientists have found that epigenetic age acceleration, as measured by four popular methylation clocks, is correlated with aging and mortality in humans [1]. Lack of human data Studying aging obviously requires having reliable biomarkers of aging. Epigenetic clocks