Category: News
Moving to a More Walkable City Increases Step Count
August 15, 2025
Working with data from a smartphone app, scientists have shown for the first time that relocating to a more walkable city is linked to increased daily step counts [1]. Most
How Inflammation Is Linked to Heart Disease
August 14, 2025
In Cell Reports Medicine, researchers have published a detailed review on the relationship between cardiovascular disease and the age-related inflammation known as inflammaging. The immune system itself ages Inflammaging occurs
Cannabis as a Treatment for Age-Related Diseases
August 13, 2025
Researchers have recently published a review on how cannabis use among older adults impacts age-related conditions and longevity [1]. Cannabinoids and longevity In recent years, researchers have observed an increase
Nir Barzilai: “Positive Evidence for Metformin is Mounting”
August 12, 2025
Dr. Nir Barzilai, the director of the Institute for Aging Research at the Albert Einstein College of Medicine, among his many other titles, is one of geroscience’s most prominent figures.
How FGF21 Fights Back Against a Muscle-Wasting Disease
August 11, 2025
In Aging, researchers have reported on how an increase in FGF21, a myokine that encourages muscle growth, impacts the progression of amyotrophic lateral sclerosis (ALS). Progressive and fatal ALS is
Mitochondria Transplant Improves Chemotherapy in Lung Cancer
August 8, 2025
Scientists have demonstrated that injecting healthy mitochondria either systematically or directly into the tumor microenvironment boosts the efficiency of a standard anti-cancer therapy [1]. Mitochondria’s dual role in lung cancer
Lifespan Alliance Launch & New Leadership at LRI
August 7, 2025
Mountain View, California — Lifespan Research Institute, a nonprofit leader in longevity science and advocacy, announces the launch of the Lifespan Alliance, a sponsorship initiative uniting mission-driven companies and visionary
A Better Extracellular Matrix Makes Aged Cells Act Youthful
August 7, 2025
Researchers have found that growing older cells in a youthful medium causes them to behave and function more like younger cells, suggesting a new method of creating stem cell-based therapies.
Nicotine Consumption Improves Motor Functions in Male Mice
August 6, 2025
A recent study reported that long-term nicotine consumption had a positive impact on motor function in male mice. The beneficial effects were mediated by sphingolipid and NAD+ metabolism [1]. Two
Study Paves Road for Oral Delivery of Proteins
August 5, 2025
Using a pathogen-originated protein and a human antibody, scientists have created a chimeric construct that can deliver protein cargo via the intestine. This technology could potentially replace cumbersome injections [1].
A Brain Clock for Finding Rejuvenating Medications
August 4, 2025
Researchers have developed a transcription-based clock that estimates brain age and used it to identify potential interventions against age-related neurodegeneration. Deciding which -omic to use While neurodegeneration and brain aging
Study Finds Metformin’s Action Is Regulated by the Brain
August 1, 2025
A new study has shown that, unlike many other glucose-lowering drugs, metformin is regulated by the protein Ras1 in a specific subset of neurons, and when injected into the brain,
Rejuvenation Roundup July 2025
August 1, 2025
Summer is heating things up, both in the Northern Hemisphere and in the world of rejuvenation biotechnology. Here’s what’s happened in July. Team and activities The 2025 Longevity Summit Dublin:
Senescent Cells, Osteoporosis, and Alzheimer’s Are Linked
July 31, 2025
Researchers publishing in Nature Aging have discovered how Alzheimer’s-related protein aggregates are also related to senescent cells and osteoporosis. Beyond the brain The amyloid tangles that result from a loss
Rejuvenating Muscles in Mice With Senomorphic Treatment
July 30, 2025
A recent study investigated senescence in mouse and human skeletal muscle tissue. The authors demonstrated that the antiviral drug maraviroc reduces senescence and improves muscle health in aged mice [1].
Moving to a More Walkable City Increases Step Count
August 15, 2025
Working with data from a smartphone app, scientists have shown for the first time that relocating to a more walkable city is linked to increased daily step counts [1]. Most of the increase consists of moderate-to-vigorous physical activity (MVPA), which is particularly healthy. A natural experiment
How Inflammation Is Linked to Heart Disease
August 14, 2025
In Cell Reports Medicine, researchers have published a detailed review on the relationship between cardiovascular disease and the age-related inflammation known as inflammaging. The immune system itself ages Inflammaging occurs in both the cells sending out signals and in the cells receiving them. The numbers of
Cannabis as a Treatment for Age-Related Diseases
August 13, 2025
Researchers have recently published a review on how cannabis use among older adults impacts age-related conditions and longevity [1]. Cannabinoids and longevity In recent years, researchers have observed an increase in cannabis use among older adults, mostly for chronic conditions, such as arthritis, pain, sleep improvement,
Nir Barzilai: “Positive Evidence for Metformin is Mounting”
August 12, 2025
Dr. Nir Barzilai, the director of the Institute for Aging Research at the Albert Einstein College of Medicine, among his many other titles, is one of geroscience’s most prominent figures. He is everywhere all at once, seemingly collaborating with the entire world, but is best known
How FGF21 Fights Back Against a Muscle-Wasting Disease
August 11, 2025
In Aging, researchers have reported on how an increase in FGF21, a myokine that encourages muscle growth, impacts the progression of amyotrophic lateral sclerosis (ALS). Progressive and fatal ALS is an age-related disease that is characterized by the degeneration of motor neurons throughout the spinal cord
Mitochondria Transplant Improves Chemotherapy in Lung Cancer
August 8, 2025
Scientists have demonstrated that injecting healthy mitochondria either systematically or directly into the tumor microenvironment boosts the efficiency of a standard anti-cancer therapy [1]. Mitochondria’s dual role in lung cancer While not the most prevalent type of cancer, lung cancer causes more deaths than any other.
Lifespan Alliance Launch & New Leadership at LRI
August 7, 2025
Mountain View, California — Lifespan Research Institute, a nonprofit leader in longevity science and advocacy, announces the launch of the Lifespan Alliance, a sponsorship initiative uniting mission-driven companies and visionary organizations dedicated to extending healthy human lifespan. Member organizations, including launch sponsors AgingBiotech.info, Immortal Dragons, Rejuve.bio,
A Better Extracellular Matrix Makes Aged Cells Act Youthful
August 7, 2025
Researchers have found that growing older cells in a youthful medium causes them to behave and function more like younger cells, suggesting a new method of creating stem cell-based therapies. Cultivating patient-derived cells For some time, mesenchymal stem cells (MSCs), which can be used to differentiate
Nicotine Consumption Improves Motor Functions in Male Mice
August 6, 2025
A recent study reported that long-term nicotine consumption had a positive impact on motor function in male mice. The beneficial effects were mediated by sphingolipid and NAD+ metabolism [1]. Two faces of tobacco smoking Smoking tobacco is widely considered detrimental to health for multiple good reasons,
Study Paves Road for Oral Delivery of Proteins
August 5, 2025
Using a pathogen-originated protein and a human antibody, scientists have created a chimeric construct that can deliver protein cargo via the intestine. This technology could potentially replace cumbersome injections [1]. Getting rid of the needle Protein-based treatments are very powerful, but they cannot yet be administered
A Brain Clock for Finding Rejuvenating Medications
August 4, 2025
Researchers have developed a transcription-based clock that estimates brain age and used it to identify potential interventions against age-related neurodegeneration. Deciding which -omic to use While neurodegeneration and brain aging are not precisely the same [1], the two are tightly linked [2]. Substantial previous work has
Study Finds Metformin’s Action Is Regulated by the Brain
August 1, 2025
A new study has shown that, unlike many other glucose-lowering drugs, metformin is regulated by the protein Ras1 in a specific subset of neurons, and when injected into the brain, even tiny doses of metformin can do the job [1]. The brain connection The safe and
Rejuvenation Roundup July 2025
August 1, 2025
Summer is heating things up, both in the Northern Hemisphere and in the world of rejuvenation biotechnology. Here’s what’s happened in July. Team and activities The 2025 Longevity Summit Dublin: The 2025 Longevity Summit Dublin was held in July, and we have the highlights from the
Senescent Cells, Osteoporosis, and Alzheimer’s Are Linked
July 31, 2025
Researchers publishing in Nature Aging have discovered how Alzheimer’s-related protein aggregates are also related to senescent cells and osteoporosis. Beyond the brain The amyloid tangles that result from a loss of proteostasis are very well-known in the context of Alzheimer’s and other neurodegenerative diseases. However, amyloid
Rejuvenating Muscles in Mice With Senomorphic Treatment
July 30, 2025
A recent study investigated senescence in mouse and human skeletal muscle tissue. The authors demonstrated that the antiviral drug maraviroc reduces senescence and improves muscle health in aged mice [1]. Aging muscle tissue Senescent cells are one of the hallmarks of aging. One of their key