Lifespan Research Institute

Category: News

Simon Melov

Dr. Simon Melov on Single Cell Genomics

Dr. Simon Melov is a professor at the Buck Institute for Research on Aging. His lab is working on identifying the molecular hallmarks of aging, specifically in the context of

Blood pressure

Carotid Bodies Play a Role in Glucose Regulation

An advance online preprint was recently released in Circulation Research examining carotid bodies’ role in hypertension and diabetes [1]. It will be published in the journal later this week. Drugs

Chloroquine Increases Maximum Lifespan in Rats by 13%

Scientists have shown that chloroquine, a well-known anti-malarial drug and the cousin of hydroxychloroquine, attenuates inflammation and fibrosis while significantly extending median and maximum lifespan in naturally aged rats [1].

Rejuvenation Roundup February

Rejuvenation Roundup February 2022

February might be the shortest month, but it’s still full of exciting research on the path towards ending age-related diseases, including senolytics and new ways of looking at epigenetics. Let’s

Brain Image

Combining Epigenetic and Imaging Biomarkers

Cardiologists, epidemiologists, and other researchers publishing in Aging have discovered that epigenetic aging and brain scans can be combined to accurately predict cognitive decline. Two entirely different measurements The ongoing

Meat on plate

Meat Consumption Increases Risk of Some Types of Cancer

In a new population study, scientists have found more evidence that consuming a lot of meat might not be a good idea, though the association between meat and cancer depends on multiple factors [1]. Diet and health Given that lifestyle changes may be the only anti-aging

Sunlight

Vitamin D Dosing Safety in a Randomized, Controlled Trial

New data has been released from the Vitamin D Type 2 Diabetes (D2d) study [1]. This study is a randomized, controlled trial that includes overweight and obese people studied at 22 academic medical centers in the United States. This data was collected between October 2013 and

Simon Melov

Dr. Simon Melov on Single Cell Genomics

Dr. Simon Melov is a professor at the Buck Institute for Research on Aging. His lab is working on identifying the molecular hallmarks of aging, specifically in the context of cellular senescence. Recently, the lab published a paper in which it announced a discovery of a

Immune cell warrior

SENS Researchers Culture Immune Cells to Fight Senescence

Publishing in Aging, a team of researchers from SENS Research Foundation has described a new method of enriching natural killer (NK) cells to fight senescent cells. Culturing NK cells to fight senescence Previous experiments have shown that natural killer (NK) cells are partially responsible for the

Exercise Improves Cognition Depending on Type and Amount

In a new review paper, scientists show that exercise can alleviate age-related cognitive decline, but not all types of exercise are created equal [1]. Watch your head Lifestyle choices, such as exercise and diet, are the most powerful anti-aging interventions currently available to us, and they

Gut bacteria

Gut Viruses Found to Improve Cognition in Humans

A study published in Cell Host & Microbe has found that members of the Cuadovirales viral order positively affect cognition in multiple species, including humans. Viruses in the human body, but not human viruses Cuadovirales is an order of bacteriophages, which infect bacteria rather than animal

Blood pressure

Carotid Bodies Play a Role in Glucose Regulation

An advance online preprint was recently released in Circulation Research examining carotid bodies’ role in hypertension and diabetes [1]. It will be published in the journal later this week. Drugs that target the glucagon-like peptide 1 (GLP1) receptor are widely used to treat type 2 diabetes

Chloroquine Increases Maximum Lifespan in Rats by 13%

Scientists have shown that chloroquine, a well-known anti-malarial drug and the cousin of hydroxychloroquine, attenuates inflammation and fibrosis while significantly extending median and maximum lifespan in naturally aged rats [1]. Fighting malaria since 1934 Chloroquine (CQ) was developed back in 1934 as an anti-malarial treatment and as

Rejuvenation Roundup February

Rejuvenation Roundup February 2022

February might be the shortest month, but it’s still full of exciting research on the path towards ending age-related diseases, including senolytics and new ways of looking at epigenetics. Let’s see what’s happened in these four weeks. LEAF News Life Noggin Joins the Lifespan.io Family: Today,

Brain Image

Combining Epigenetic and Imaging Biomarkers

Cardiologists, epidemiologists, and other researchers publishing in Aging have discovered that epigenetic aging and brain scans can be combined to accurately predict cognitive decline. Two entirely different measurements The ongoing CARDIA study was started in 1985 to monitor coronary artery risk development in young adults (who

Rat Look

Resveratrol Ameliorates Erectile Dysfunction in Old Rats

Scientists have shown that resveratrol rescues erectile function in aged rats, most probably by activating SIRT1, and that it can work in synergy with the existing erectile dysfunction treatment tadalafil [1]. A molecule of discord Resveratrol, a plant-derived chemical of the polyphenol family, was once considered

Running Mice

The Effects of Early Life Rapamycin Administration on Mice

A team of researchers, including Steve Horvath, Leonid Peshkin, and Vadim Gladyshev, has published a preprint on bioRxiv showing the effects of early administration of rapamycin over the lifespans of mice. Rapamycin before and after weaning In this placebo-controlled experiment, the researchers selected the UMHET3 strain

Skeletal Muscle

Urolithin A Affects Muscle and Mitochondria in Older Adults

A study published in the Journal of the American Medical Association has examined the dosage and safety of a urolithin A supplement [1]. This study also examined urolithin A‘s effect on muscle endurance and specific health biomarkers. A randomized, controlled clinical trial  This study is a

Exercising man

NAD+ Levels Are Correlated with Physical Activity in Humans

In a study published in Nature Aging, a group of scientists has shown that NAD+ levels are correlated not only with age but with physical activity, with elder athletes rivaling normal young adults [1]. NAD: small, crucial, age-related Nicotinamide adenine dinucleotide (NAD) is as important as

Pankaj Kapahi Interview

Dr. Pankaj Kapahi: “AGEs are a Trillion-Dollar Industry”

Dr. Pankaj Kapahi is a veteran geroscientist. His laboratory at the famous Buck Institute for Research on Aging is among the few that study advanced glycation end products (AGEs) and the many ways in which they affect aging. Dr. Kapahi’s company, Juvify, produces GLYLO, a supplement