Lifespan Research Institute

Category: News

Osteoarthritis

The Effects of Physical Activity on Frailty

A new study shows that even low levels of physical activity are very good for your muscles, bones, and joints, but exercising too much can potentially harm you [1]. The

EARD2021 Tina Woods

Tina Woods on a Longevity Ecosystem at EARD2021

At Ending Age-Related Diseases 2021, Elena Milova of Lifespan.io interviewed Tina Woods on the development of a longevity ecosystem, the importance of language, and the social aspects of extending lifespans.

Obese mouse

A Vaccine for High Cholesterol Works in Mice

Researchers publishing in Cell Reports Medicine have discovered that a vaccine targeting angiopoietin-like protein 3 (ANGPTL3) alleviates dyslipidemia and improves outcomes in obese mice. What is dyslipidemia? Dyslipidemia is marked

Raw hot peppers are a source of quercetin.

What Is Quercetin? A Summary of Quercetin

Found in many fruits and vegetables, quercetin may have some potential in the context of aging. Here, we take a look at this natural antioxidant and popular dietary supplement. What

Elderly brain

Old Serum Shown to Kill Brain Stem Cells

A study published in Aging and Disease has shown how exposure to old serum causes hippocampal progenitor cells (HPCs), which form new neurons, to die. Drawing and testing serum from

Plant-Based Diet

Plant-Based Diet Linked To Reduced Leaky Gut Syndrome

The MaPLE trial in Italy investigated whether or not increasing fruits and vegetables decreases leaky gut syndrome [1]. Background This study examines increased intestinal permeability (leaky gut) in adults 60

Grape seeds

A Grape seed Extract Slows Aging In Mice

Studying grape seed extract, scientists have discovered a new senomorphic compound that enhances chemotherapy and prolongs lifespan and healthspan in mice [1]. Nature’s drugstore Many drugs have come to us

Olives

Olive Derivative Fights Epigenetic Kidney Aging

Researchers publishing in Aging Cell have discovered how and why oleuropein (OLP), a polyphenol derived from olives, ameliorates epigenetic kidney aging. Upregulation and downregulation Like nearly everything in biology, this

Brain Blood Vessels

Viagra Identified as a Candidate Drug for Alzheimer’s

After sifting through 1,600 FDA-approved drugs, scientists have shown that Viagra is significantly correlated with lower Alzheimer’s disease risk [1]. Re-repurposing Viagra? Viagra (sildenafil) is one of the most recognizable

Chinese Licorice

Chinese Licorice Plant Extract Restores Fat Stem Cells

Researchers publishing in Aging have reported that licochalcone A (LA), a flavonoid that originates from Chinese licorice, restores human adipose-derived stem cells (hADSCs) in cell culture. Reported positive effects Previous

Umbilical Cord

Demonstration That Cord Blood Improves Progeria

A new case report published in the International Journal of Molecular Sciences highlights cardiovascular improvements in a patient with Hutchinson-Gilford progeria treated with umbilical cord blood. A case study using

Gene transcription

Hyperbaric Oxygen Causes Transcriptomic Changes

Transcriptomic results have been published regarding the Shamir Medical Center longitudinal study on hyperbaric oxygen therapy (HBOT), which was conducted between 2016 and 2020 on 35 healthy adults aged 64

Osteoarthritis

The Effects of Physical Activity on Frailty

A new study shows that even low levels of physical activity are very good for your muscles, bones, and joints, but exercising too much can potentially harm you [1]. The unholy trinity Sarcopenia, osteoporosis, and osteoarthritis are the trio of age-related diseases that affect, respectively, muscles,

EARD2021 Tina Woods

Tina Woods on a Longevity Ecosystem at EARD2021

At Ending Age-Related Diseases 2021, Elena Milova of Lifespan.io interviewed Tina Woods on the development of a longevity ecosystem, the importance of language, and the social aspects of extending lifespans. Script Elena: Greetings to the participants of Ending Age-Related Diseases 2021. This conference brings together thought

Obese mouse

A Vaccine for High Cholesterol Works in Mice

Researchers publishing in Cell Reports Medicine have discovered that a vaccine targeting angiopoietin-like protein 3 (ANGPTL3) alleviates dyslipidemia and improves outcomes in obese mice. What is dyslipidemia? Dyslipidemia is marked by having an excess of low-density lipoprotein (LDL) cholesterol, a lack of high-density lipoprotein (HDL) cholesterol,

Raw hot peppers are a source of quercetin.

What Is Quercetin? A Summary of Quercetin

Found in many fruits and vegetables, quercetin may have some potential in the context of aging. Here, we take a look at this natural antioxidant and popular dietary supplement. What is quercetin? Quercetin is a natural flavonoid, which makes it part of a large family of

Optimistic outlook

NewLimit: A New Biotech Working on Epigenetic Aging

Two investors, including a co-founder of Coinbase, have announced a new biotech venture that aims to solve aging by studying its epigenetic aspects. New kid on the block Long gone are the times when longevity biotech companies were scarce and poorly funded. Today, barely a week

Elderly brain

Old Serum Shown to Kill Brain Stem Cells

A study published in Aging and Disease has shown how exposure to old serum causes hippocampal progenitor cells (HPCs), which form new neurons, to die. Drawing and testing serum from living people To begin their study, the researchers examined a middle-aged to old (MATO) cohort ranging

Plant-Based Diet

Plant-Based Diet Linked To Reduced Leaky Gut Syndrome

The MaPLE trial in Italy investigated whether or not increasing fruits and vegetables decreases leaky gut syndrome [1]. Background This study examines increased intestinal permeability (leaky gut) in adults 60 years and older [1].  Age has been reported to be a risk factor for increased intestinal

Stethoscope Clock

Epigenetic Clock Shows Association With Cardiovascular Aging

A new study published in Mechanisms of Ageing and Development has found correlations between cardiovascular aging and a measure of epigenetic age acceleration [1]. Can epigenetic clocks predict cardiovascular disease? One way researchers test the validity and usefulness of epigenetic clocks is to compare their outputs

Grape seeds

A Grape seed Extract Slows Aging In Mice

Studying grape seed extract, scientists have discovered a new senomorphic compound that enhances chemotherapy and prolongs lifespan and healthspan in mice [1]. Nature’s drugstore Many drugs have come to us from the world of plants, including promising geroprotective molecules such as resveratrol. However, identifying specific components

Olives

Olive Derivative Fights Epigenetic Kidney Aging

Researchers publishing in Aging Cell have discovered how and why oleuropein (OLP), a polyphenol derived from olives, ameliorates epigenetic kidney aging. Upregulation and downregulation Like nearly everything in biology, this specific part of kidney aging results from a chain of events. Here, the researchers show that

Brain Blood Vessels

Viagra Identified as a Candidate Drug for Alzheimer’s

After sifting through 1,600 FDA-approved drugs, scientists have shown that Viagra is significantly correlated with lower Alzheimer’s disease risk [1]. Re-repurposing Viagra? Viagra (sildenafil) is one of the most recognizable drugs in the world. Yet, sildenafil’s hailed effect on erectile dysfunction was discovered serendipitously. Originally, sildenafil

Chinese Licorice

Chinese Licorice Plant Extract Restores Fat Stem Cells

Researchers publishing in Aging have reported that licochalcone A (LA), a flavonoid that originates from Chinese licorice, restores human adipose-derived stem cells (hADSCs) in cell culture. Reported positive effects Previous research on Licochalcone A has discovered that it has anti-inflammatory and anti-tumor effects [1], reduces obesity

Umbilical Cord

Demonstration That Cord Blood Improves Progeria

A new case report published in the International Journal of Molecular Sciences highlights cardiovascular improvements in a patient with Hutchinson-Gilford progeria treated with umbilical cord blood. A case study using umbilical cord blood  Cell therapy has shown potential in treating cardiovascular disease, which is also the

Gene transcription

Hyperbaric Oxygen Causes Transcriptomic Changes

Transcriptomic results have been published regarding the Shamir Medical Center longitudinal study on hyperbaric oxygen therapy (HBOT), which was conducted between 2016 and 2020 on 35 healthy adults aged 64 and older [1]. Background Recently, we discussed misconceptions from the media on research developing on HBOT

Nematode

Late-Life Treatment Extends Nematode Lifespan by Two-Fold

Scientists have managed to extend the lifespan of C. elegans nematode worms by as much as 135% by blocking an insulin-related pathway very late in life [1]. The long-lived mutants Back in the late 80s and early 90s, experiments with C. elegans, tiny nematode worms, became