Category: News
Potential Mechanisms Behind Skin Aging Identified
October 27, 2021
The latest research out of the Journal of Cell Biology shines a light on why our skin loses its healing abilities as we age. The skin’s ability to regenerate dramatically
Cellular Senescence: It’s Complicated, but There’s Hope
October 26, 2021
Two of the most prominent experts in the field have published a review of cellular senescence in the context of metabolism, and we bring you the highlights [1]. We rarely
Resveratrol Aids Spinal Cord Regeneration in Rats
October 25, 2021
A team of researchers publishing in Aging have shown that resveratrol reduces inflammation and partially restores function in a rat model of spinal injury. In line with previous research This
New Mechanism of Neurodegeneration Identified
October 22, 2021
Researchers have identified an important mechanism of neurodegeneration that may be useful in treating age-related diseases such as Alzheimer’s and dementia [1]. These neurons must die Age-related neurodegenerative diseases, including
Targeted clearance of senescent cells
October 22, 2021
The next Journal Club will be on Tuesday 2nd November and Dr. Oliver Medvedik will be taking a look at a new paper called “Targeted clearance of senescent cells using
Journal Club October 2021 – Targeted clearance of senescent cells
October 22, 2021
The next Journal Club will be on Tuesday 2nd November and Dr. Medvedik will be taking a look at a new paper called “Targeted clearance of senescent cells using an
Energy Metabolism Decline Linked To Alzheimer’s
October 21, 2021
Researchers publishing in Aging have discovered that an energy metabolism compound is associated with a protein that suppresses amyloid beta in a mouse model of Alzheimer’s. The compounds involved The
Lack of Klotho Associated With All-Cause Mortality
October 20, 2021
A recent study in The Journals of Gerontology, Series A has associated low klotho levels with mortality in Americans over the age of 40. Klotho and aging Prediction of mortality
Scientists Propose a New Targeted Senolytic
October 19, 2021
A group of researchers has developed a delivery system that identifies senescent cells and injects them with a deadly compound. This offers a potential solution to the problem of targeted
NR Temporarily Improves Immune Function in Mice
October 18, 2021
A study published in the Nature journal Aging and Mechanisms of Disease has shown that supplementation with nicotinamide riboside (NR) substantially improves the immune systems of older mice due to
$70 Million Rejuvenome Initiative Launches
October 15, 2021
Recently, the Astera Institute has announced that it will be collaborating with the Buck Institute on its Rejuvenome project. The project is a focused research organization (FRO), a new model
Allele Associated With Alzheimer’s Improves Cognition
October 15, 2021
Scientists have demonstrated that “the Alzheimer’s allele” APOE e4 helps cognition earlier in life prior to the onset of the disease [1]. This might point at a possible reason for
A Path Towards Restoring Thymic Function
October 14, 2021
A study published in Cell Reports shows how the thymus is stimulated to repair itself when dying thymocytes are depleted, paving the way towards novel methods of thymic regeneration. Cycles
Dylan Livingston: Increasing Healthy Lifespan Is Bipartisan
October 14, 2021
Dylan Livingston is the founder and president of A4LI – the Alliance for Longevity Initiatives. This newly created organization aims to fill an important niche as a non-profit that would
The Genetic Basis of Telomere Length
October 13, 2021
A new study in Nature Genetics has further illuminated the genetic regulation of telomere length and what implications it may have for various diseases and longevity. Telomeres and aging in
Potential Mechanisms Behind Skin Aging Identified
October 27, 2021
The latest research out of the Journal of Cell Biology shines a light on why our skin loses its healing abilities as we age. The skin’s ability to regenerate dramatically decreases with age. Injuries that would have healed in days without a trace in childhood can
Cellular Senescence: It’s Complicated, but There’s Hope
October 26, 2021
Two of the most prominent experts in the field have published a review of cellular senescence in the context of metabolism, and we bring you the highlights [1]. We rarely cover review papers, but when Cristopher D. Wiley and Judith Campisi, two of the most prominent
Resveratrol Aids Spinal Cord Regeneration in Rats
October 25, 2021
A team of researchers publishing in Aging have shown that resveratrol reduces inflammation and partially restores function in a rat model of spinal injury. In line with previous research This is far from the first study that aimed to use approaches associated with aging research in
New Mechanism of Neurodegeneration Identified
October 22, 2021
Researchers have identified an important mechanism of neurodegeneration that may be useful in treating age-related diseases such as Alzheimer’s and dementia [1]. These neurons must die Age-related neurodegenerative diseases, including Parkinson’s and Alzheimer’s, have become more prevalent mostly because of the successes of modern medicine. Today,
Targeted clearance of senescent cells
October 22, 2021
The next Journal Club will be on Tuesday 2nd November and Dr. Oliver Medvedik will be taking a look at a new paper called “Targeted clearance of senescent cells using an antibody-drug conjugate against a specific membrane marker“. Join us live on Facebook at 1 PM
Journal Club October 2021 – Targeted clearance of senescent cells
October 22, 2021
The next Journal Club will be on Tuesday 2nd November and Dr. Medvedik will be taking a look at a new paper called “Targeted clearance of senescent cells using an antibody-drug conjugate against a specific membrane marker“. Join us live on the call at 1 PM
Energy Metabolism Decline Linked To Alzheimer’s
October 21, 2021
Researchers publishing in Aging have discovered that an energy metabolism compound is associated with a protein that suppresses amyloid beta in a mouse model of Alzheimer’s. The compounds involved The researchers describe nicotinamide mononucleotide adenylyltransferase 2 (Nmnat2) as a key co-factor for energy metabolism. This compound
Lack of Klotho Associated With All-Cause Mortality
October 20, 2021
A recent study in The Journals of Gerontology, Series A has associated low klotho levels with mortality in Americans over the age of 40. Klotho and aging Prediction of mortality is a major interest of the aging field and the broader medical field. Epigenetic clocks, senescent
Scientists Propose a New Targeted Senolytic
October 19, 2021
A group of researchers has developed a delivery system that identifies senescent cells and injects them with a deadly compound. This offers a potential solution to the problem of targeted delivery of senolytics [1]. Cellular senescence has been implicated in numerous aging-related disorders, including fibrosis, diabetes,
NR Temporarily Improves Immune Function in Mice
October 18, 2021
A study published in the Nature journal Aging and Mechanisms of Disease has shown that supplementation with nicotinamide riboside (NR) substantially improves the immune systems of older mice due to its effects on stem cell fate. However, the benefits do not persist after NR is removed.
$70 Million Rejuvenome Initiative Launches
October 15, 2021
Recently, the Astera Institute has announced that it will be collaborating with the Buck Institute on its Rejuvenome project. The project is a focused research organization (FRO), a new model of organization that is laser-focused on a specific scientific challenge that cannot be solved by existing
Allele Associated With Alzheimer’s Improves Cognition
October 15, 2021
Scientists have demonstrated that “the Alzheimer’s allele” APOE e4 helps cognition earlier in life prior to the onset of the disease [1]. This might point at a possible reason for some aspects of aging. What makes us stronger kills us later The risk of developing Alzheimer’s,
A Path Towards Restoring Thymic Function
October 14, 2021
A study published in Cell Reports shows how the thymus is stimulated to repair itself when dying thymocytes are depleted, paving the way towards novel methods of thymic regeneration. Cycles of involution, not a steady decline The researchers cite previous research showing that the thymus, despite
Dylan Livingston: Increasing Healthy Lifespan Is Bipartisan
October 14, 2021
Dylan Livingston is the founder and president of A4LI – the Alliance for Longevity Initiatives. This newly created organization aims to fill an important niche as a non-profit that would educate American politicians on life extension and promote policy changes beneficial for our cause. How can
The Genetic Basis of Telomere Length
October 13, 2021
A new study in Nature Genetics has further illuminated the genetic regulation of telomere length and what implications it may have for various diseases and longevity. Telomeres and aging in humans At one time the hottest topic in aging, telomeres are the protective caps at the