October 24, 2025
A study from Rockefeller University suggests that an unholy duo of two proteins causes harm in much lower concentrations than either of them alone. This points to a possible route for intervention [1]. When amyloid met fibrinogen Amyloid beta (Aβ) and tau proteins are the usual suspects in Alzheimer’s disease. However, focusing on either of...
October 30, 2023
Researchers publishing in GeroScience have discovered the molecular mechanisms through which fibrinogen, a protein that increases with aging, causes toxic compounds to more easily leak into the brain. The deteriorating blood-brain barrier In the brain, the microvessels (MVs) that are responsible for carrying blood to neurons and other cells provide careful filtration, both from infectious...

