January 14, 2026
A recent review of literature investigated the risks and benefits of hormone replacement therapy. The authors point out that this approach could be used as a geroprotector to extend the healthspan of women. However, the risk-benefit ratio should be individually evaluated. [1] Sex-specific aging trajectories Female and male aging trajectories differ, and one contributor is...
June 18, 2025
Analysis of over a thousand postmenopausal women suggests that women with longer reproductive spans, earlier first period (menarche), and later menopause experience slower brain aging [1]. Linking sex hormones to brain health The female reproductive system fails to work properly much earlier than other systems in the human body. The aging of the reproductive system...
March 31, 2025
In the Journal of Endocrinological Investigation, reviewers have described how aging affects the adrenal glands, which has downstream effects on the rest of the human body. Small but vital This paper begins with an in-depth description of the anatomy of the adrenal glands, which sit atop the kidneys, and the various hormones that each of...
June 07, 2023
Research published in Aging Cell has discovered that castrated male mice show similarities to females in growth and lifespan [1]. It is widely known that women outlive men on average, but the biological reasons are still not fully understood. As it is challenging to experimentally test these reasons in humans, researchers turned to a special...



