Tag: IL-6

Researchers publishing in Aging have used Mendelian randomization to conclude that the inflammatory factor IL6 causes increased mortality and that its circulating receptor, IL6R, decreases it. Looking for a proof of danger Chronic InflammationChronic inflammation refers to a persistent, low-grade buzz of immune activity that settles into the body without the drama of an infection...

Researchers have discovered that butyrate, a short-chain fatty acid with well-documented gut benefits, fights senescence in T cells. Immune senescence drives inflammaging Cellular SenescenceAs your body ages, more of your cells become senescent. Senescent cells do not divide or support the tissues of which they are part; instead, they emit potentially harmful chemical signals, collectively...

In Aging, researchers have reported that deriving extracellular vesicles from mesenchymal stromal cells (MSCs) in fat tissue has beneficial effects in models of osteoarthritis. Which source to use? Cellular SenescenceAs your body ages, more of your cells become senescent. Senescent cells do not divide or support the tissues of which they are part; instead, they...

In Aging Cell, researchers have published their findings into why the inflammatory factor IL-6 inhibits cancerous tumors when generated inside the cell. IL-6 affects both senescence and cancer proliferation Cellular SenescenceAs your body ages, more of your cells become senescent. Senescent cells do not divide or support the tissues of which they are part; instead,...

A team of researchers has waded into a controversial and contradictory area of study, publishing information on the link between obesity and an inflammatory molecule that increases with aging. A context-dependent molecule The authors point out previous research that singled out the interleukin IL-6, a key immune signaling molecule, as a major contributor to inflammaging...

Researchers publishing in Aging have explained a relationship between inflammation, metabolic syndrome, and prostate enlargement. Not so benign Benign prostatic hyperplasia (BPH) is only called 'benign' to differentiate it from another well-known cause of prostate enlargement: prostate cancer. BPH is known to lead to bladder obstruction and lower urinary tract issues. It also coincides with...