Tag: Neurogenesis

Scientists have found that partial cellular reprogramming, both full-body and restricted to specific brain regions, rescues neurogenesis in the brains of old mice [1]. Cells going back in time Yamanaka Factors - Opportunities for RejuvenationDrs. Takahashi and Yamanaka showed that they could use Oct4, Sox2, Klf4, and c-Myc (OSKM) to reprogram cells back to pluripotent, embryonic...

New research published in Brain investigated the influence of fecal microbiota transplants from Alzheimer’s patients on cognitive function and neurogenesis in rats and human cell cultures [1]. Microbiota-gut-brain axis There is a growing body of research reporting changes to the composition and metabolites in the microbiomes of Alzheimer’s patients [2]. Studies have also linked the...

Researchers have identified a platelet-derived factor that improves cognition in mice and published their findings in Nature Communications. Finding the right molecules This paper begins with the same refrain common in discussions about the biological effects of exercise: the inability of some older people to conduct exercise in any real capacity and therefore the need...

Scientists have shown that the protein GDF11 can reverse depression-like symptoms in naturally aged mice and in a mouse model of depression. Depressed humans have lower GDF11 as well [1]. Depression and aging Severe mental disorders, including depression, have been linked to significantly shorter lifespans [2]. According to one study, depressed people “have a higher...

Scientists have found that infusing old mice with cerebrospinal fluid obtained from young mice improves their memory by increasing proliferation and differentiation of oligodendrocyte progenitor cells (OPCs) [1]. The fountain of brain youth It has been known for years that blood from young animals can alleviate or even reverse some age-related changes, including cognitive changes,...

Publishing in Aging, a team of Taiwanese researchers has found that a chemical derived from Polygonum multiflorum, a herb native to southeastern China, aids in recovery from traumatic brain injury and encourages brain regeneration. The problem of glutamate BrainThe brain is perhaps the most important organ in the body. While many organs are critical to...