April 14, 2025
In Aging, Dr. Sajid Zalzala and his team have published the results of Participatory Evaluation of Aging with Rapamycin for Longevity (PEARL), a randomized, controlled human clinical trial that was crowdfunded by Lifespan.io. Crowdfunded research bears fruit Rapamycin: Benefits, Side Effects, and ResearchRapamycin is a macrolide, a class of antibiotic and it exhibits potent antitumor...
October 07, 2024
For those of us living in the Northern Hemisphere, the summer days are gone and the cooler days of fall have arrived. While it’s time to ditch the beachwear for chunky sweaters and a hot chocolate by the fire, things have been heating up in the longevity space. Lifespan merges with SENS Research Foundation Lifespan.io...
June 18, 2021
Today is a doubly important day: it marks the final day of the PEARL campaign and it is a celebration of another victory for the life extension community. PEARL smashed its initial fundraising goal and sailed through its two stretch goals, raising just under $183k thanks to the generous support of the community. What is...
June 11, 2021
Researchers have demonstrated that rapamycin, a drug that has long been believed to slow down aging, changes the way DNA is stored inside cells to support gut health and longevity [1]. This improvement to DNA storage has been observed in both fruit flies and mice in the lab, and the researchers believe that those benefits...
June 03, 2021
We are very excited to be crowdfunding PEARL, one of the few human trials of rapamycin, which is probably the most promising anti-aging molecule known today. Dysregulation of nutrient sensing (the ability of cells to adjust their metabolism to the amount of nutrients available) is thought to be one of the nine hallmarks of aging....
May 28, 2021
Today, we want to announce we are doing an AMA on Reddit Futurology! The Ask Me Anything thread will be open May 28 and 29 for pre-questions, and on May 30 and 31, the PEARL team will be answering questions. This is your opportunity to ask questions about the project, which aims to launch human...