Tag: Stem Cells

Researchers publishing in Aging Cell have discovered that cells derived from the human placenta may be useful in estimating the effects of potential anti-aging treatments. A seemingly odd choice Of all the organs in the body, the placenta may be the least concerning with regards to aging; it only exists for at most 10 months,...

In Aging Cell, four Japanese researchers have recently described the aging of the hematopoietic system, which is responsible for the creation of blood. A system that affects all the others Aging and age-related diseases are often discussed in terms of hallmarks, such as senescence and genomic instability. However, the bodies of complex organisms, such as...

Scientists have genetically modified human mesenchymal progenitor cells to express a more potent version of the “longevity gene” FOXO3, producing rejuvenative effects in monkeys, mice, and human cells [1]. Making aging-resistant cells Stem cell exhaustion is one of the mechanisms of aging. Replenishing the aging stem cell pool with new exogenous cells sounds like a...

In Cell Stem Cell, researchers from the Cedars-Sinai Medical Center have published a review discussing what experiments conducted in space can do for stem cell research and medical research as a whole. Cells behave differently in microgravity The gravitational effects of freefalling in orbit are very difficult to properly simulate on Earth, making this the...

Researchers have found that growing older cells in a youthful medium causes them to behave and function more like younger cells, suggesting a new method of creating stem cell-based therapies. Cultivating patient-derived cells For some time, mesenchymal stem cells (MSCs), which can be used to differentiate into multiple functional cell types, were thought to be...

Researchers publishing in Cell Stem Cell have investigated the function of the gene DNMT3A and found that it has wide-ranging effects beyond methylation. More effects than expected Clonal hematopoiesis (CH), which occurs when stem cells create large numbers of cells with the same mutation, is linked to blood cancers [1]. DNMT3A is the most commonly...