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Tag: Urolithin A

Intestinal inflammation
In a preprint study, scientists from Lifespan Research Institute and the Buck Institute for Research on Aging have published their findings that Urolithin A, a molecule that has garnered a lot of attention in the longevity field, potently reduces senescence-related markers in human fibroblasts [1]. Senolytic versus senomorphic Cellular senescence is a well-documented aspect of...
Exercising Elderly
A new study published in Cell Reports Medicine shows that urolithin A supplementation improves muscle strength, fitness, and mitochondrial health in overweight, middle-aged adults [1]. Mitophagy in aging and in disease Mitochondrial dysfunction is one of the hallmarks of aging. It is associated with age-related skeletal muscle deterioration, which leads to such functional impairments as...
Skeletal Muscle
A study published in the Journal of the American Medical Association has examined the dosage and safety of a urolithin A supplement [1]. This study also examined urolithin A's effect on muscle endurance and specific health biomarkers. A randomized, controlled clinical trial  This study is a follow-up to prior work done by the Amazentis company,...